Hers Skincare Review: Do Their Prescription Creams Work? 

Hers Skincare Review
Hers offers prescription skin care creams for women, one for acne and one for anti-aging. Thankfully, our honest review answers the question; do they actually work?

We review and include products we think are useful for our community. If you buy through links on this page, we may earn a commission. For more info, please read our ad policy, content principles and vetting policy.

Published by Bridget Reed on February 2, 2024

Hers Skin Care | Rx Procedures | Tretinoin | Niacinamide | Clindamycin | Reviews

Skin care often takes a back seat in the world of health and wellness. Its importance gets overshadowed by other health considerations, like heart, immune, and brain health.

Of course, these body systems can’t be overlooked either — where would we be without them?

All we are saying is that skin care deserves some love too. As the largest organ, skin provides us with a covering from the harsh environment. Our skin can also tell us a lot about our overall health.

Hers Skincare Review
Hers Skincare Review

Things like dryness, rashes, and acne can send us warning signs, alerting us to potential vitamin deficiencies, diseases, excess sun exposure, or toxins in the body.

A good skin care routine should be part of every person’s daily regiment, women and men alike. The vast array of products can be a bit overwhelming — cleansers, toners, moisturizers, exfoliates, serum, sunscreens, and on and on.

However, sometimes prescription skin care products are needed to combat certain conditions; such as acne.

Hers, a telemedicine company, looks to provide women with prescription skin care products; aimed specifically at acne treatment and anti-aging.

This online provider seeks to provide convenience and accessibility when it comes to female-specific health and wellness.

But do their prescription skin care creams actually work? Are they effective in treating acne and the effects of aging?

Stick around while this review seeks to uncover the answers to these important questions.

Hers Skin Care Creams

It is clear that skin health is important to overall wellness. In terms of prescription Hers skincare, Hers has two products: Acne Cream and Anti-Aging Cream. 

Both are meant to serve a variety of skin types.

Clinically speaking, most people’s skin falls into two categories:

  • Dry Skin: Flaky, itchy, rough skin; moisture is required. 
  • Oily Skin: Some people have an overproduction of sebum, resulting in shiny, greasy, oily type skin. 

Of course, some people deal with a combination of both; having some dry areas and some oily areas. 

Before we dive into each skin care cream, let’s take a quick look at how they handle their prescription process. 

Hers Prescription Procedure

To enjoy the benefits of Hers skin care products you must first consent to an online consultation with one of their medical professionals.

These medical professionals will make the final decision in determining if their dermatologist-developed prescription creams are right for you.

Keep in mind, the purpose of the consultation is to ensure the potential prescription is tailored to you. It is not a one size fits all approach.

The initial consultation features a survey, asking questions that pertain to you, your skin, medical history, and medications.

You must also be ready to upload pictures of your face. All in all, the process takes around 15 to 20 minutes.

After the data is compiled, Hers will match you with a provider who determines your personalized treatment and ultimately writes the prescription.

If you proceed, the prescription cream will be mailed straight to your door. Currently, Hers prescription cream service ranges from $5-10 / month at its introductory offer rate. Not a bad price.

Their support center ensures customer follow-up questions are answered. Customers can also consult with medical providers if they have concerns or want to request changes in prescriptions.

Anti-aging face cream
Anti-Aging Cream | Hers

Anti-Aging Cream | Hers

The truth is, we’re not trying to look 18 again—but looking like we get a solid 8 hours of sleep would be nice. Enter the Anti-Aging Cream, made with prescription tretinoin: a prescription-strength vitamin A derivative scientifically proven to improve the texture and quality of skin and the appearance of fine lines. Here’s to giving good face.

  • Prescription tretinoin
  • Helps smooth fine lines
  • Tailored to specific skin needs

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#1 Best Selling Rx Acne Cream
Acne Cream | Hers

Acne Cream | Hers

When you’ve tried everything on your stubborn acne, it’s time to explore a personalized prescription. Tailored to treat specific acne needs, this cream is made of a customized blend of up to five powerhouse ingredients: tretinoin, clindamycin, azelaic acid, zinc pyrithione, and niacinamide.

01 Stops acne in its tracks
02 Prevents future breakouts
03 Custom to your skin


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Acne Cream
Tidal Wave Moisturizer | Hers

Tidal Wave Moisturizer | Hers

Your acne-clearing routine wouldn’t be complete without the moisturizing basics designed to go with it. Because you don’t just want clear skin—you want hydrated skin, too. Enter the Tidal Wave Moisturizer: a gentle cream that hydrates skin without clogging it up.

01 Hyaluronic acid and squalane
02 Gentle on acne-prone skin
03 Part of our Clear Skin System


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Acne Cream
Deep Sea Cleanser | Hers

Deep Sea Cleanser | Hers

The idea of having hydrated skin while treating adult acne or blemishes might feel just a bit far-fetched. But the truth is, it’s possible—all you need is a gentle cleanser that won’t strip your skin of oils or block your pores. We call it the Deep Sea Cleanser. Made with red seaweed extract and rosehip seed, it’s gentle on acne-prone skin without sacrificing the hydration your skin needs.

01 Hydrating facial cleanser
02 Gentle on acne-prone skin
03 Part of our Clear Skin System


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Prescription Acne Cream

The acne treatment market is quite big, bringing in billions of dollars a year globally. Of course, that isn’t without reason.

According to the American Academy of Dermatology, acne is one of the most common skin conditions in the United States, affecting nearly 50 million people every year.

But acne is not a skin condition reserved only for hormonal teenagers. It can occur at any stage of life; in fact, acne occurrence in adults is on the rise, especially among women.

What is Acne?

Simply put, acne is a skin condition that occurs as a result of clogged hair follicles under the skin.

However, there are many types of acne, from simple blemishes to blackheads and they vary in severity: mild, moderate, and severe.

  • Whiteheads – These are the results of clogged skin pores; usually due to excess skin debris and sebum (basically an oil in the skin). Most times, these are the closed “pimples” people refer to. 
  • Blackheads – These develop similarly to whiteheads. The main difference lies in appearance. These are closed and darker in color. 

Papules and pustules are other forms of acne that present as red, inflammatory lesions and are the result of bacteria.

Hormonal acne develops as a result of hormone fluctuations in the body; the ones experienced during puberty or menstruation. 

How Do Acne Creams Work?

Prescription acne creams usually have two primary goals: stopping active acne, and preventing future acne breakouts.

Remember, the prescription acne cream from Hers is customized and personalized specifically for your skin. Your prescription formula is developed after the consultation and professional assessment.

Hers uses a special blend of five active ingredients for their Prescription Acne Cream: tretinoin, niacinamide, clindamycin, azelaic acid, and zinc pyrithione.

For our purposes here, we will only focus on the first three. Let’s take a closer look.


Tretinoin is one of the most common topical medications used to treat acne and other skin conditions. It is sometimes referred to as retinoic acid. Tretinoin is basically a synthetic version of vitamin A. 

Various research studies have shown the effectiveness of topical tretinoin for treating acne:

  • It helps reduce the inflammation associated with acne.
  • It helps prevent plugging of follicles (which causes acne).
  • It increases the rate of skin cell turnover, helping to clear up acne.


Niacinamide is a form of vitamin B3, i.e. niacin. It is naturally found in many foods and supplements and is found in combination alongside other popular acne treatment ingredients. 

In terms of acne treatment, research shows niacinamide to be an effective topical ingredient. It helps by: 

  • Reducing redness and blotching of skin, which is typical with acne.
  • Regulating skin oils, retaining moisture and reducing sebaceous oil produces (which clogs pores).
  • Plus, it has antioxidant effects, fighting oxidative stressors (environmental, photodamage, and toxins).


As an acne treatment ingredient, clindamycin is found in topical form and in combination as an antibiotic. Oftentimes, clindamycin is found alongside tretinoin or benzoyl peroxide.

As noted above, acne can often be the result of bacteria. Clindamycin, as a topical antibiotic, has proven beneficial in reducing acne-causing bacteria.

In fact, according to the American Academy of Dermatology, clindamycin is often the first line of acne treatment recommended by dermatologists.

Since it’s a prescription, the acne cream should only be used as directed by the dermatologist.

However, Hers does have some advice to help you achieve the best results.

  • First, before applying the acne cream, they recommend using a cleanser to help remove dirt and oils. They of course recommend their Deep Sea Cleanser.
  • Next, you apply the customized acne cream as directed.
  • Finally, they recommend using a moisturizer (Tidal Wave Moisturizer) with hyaluronic acid to lock in moisture.

According to Hers, some women do experience side effects. Some of the common side effects of the acne cream are skin irritation, redness, itching, and peeling. They also warn that sun exposure while using acne cream could increase skin sensitivity.

Does It Actually Work?

Personalized prescription medicines that are just that — personalized. The effectiveness relies on the person’s compliance with the use and consistency.

Typically, Hers says that most customers see marked improvements in a few months.

Plus, they offer a 90-day money back guarantee if you aren’t satisfied with the results — a huge incentive to give it a try.

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Hers Total Review

Here a few customer reviews that shed some light on the overall effectiveness of their prescription acne cream:

“I’ve struggled with worsening acne for almost 20 years. After 3 months of using the Hers acne treatment my acne is nearly gone!”

  • Heather, 5/5 Stars on Trustpilot

“I’ve suffered from acne all my adult life and tried almost every acne products/prescriptions out there . I’ve been using hers skin care for about 3 weeks and my skin has improved significantly. The best thing is seeing the improvements when I wake in the morning. I cannot wait to go to the bathroom and look at my skin. This is heaven sent.”

  • Aldeen, 5/5 Stars on Trustpilot

Anti-Aging Prescription Skin Cream

The second product we will look at is Hers’ Anti-Aging Cream

According to Hers, this prescription cream seeks to help smooth fine lines, reduce uneven skin textures, alleviate dark spots, and boost collagen production. That is quite a list of benefits.

At the end of the day, the anti-aging cream is meant to be a part of the skin care routine. Anti-aging treatments and serums are usually formulated and highly concentrated and used to address common skin issues due to aging — dullness, wrinkles, dryness, and spots.

A quick word about wrinkles… 

Some people are proud of the wrinkles they’ve earned in life, others shudder at the thought. But how do we get them?

Well, they develop over time, but some of the most common factors that help produce them are photoaging and decreased collagen production.

Photoaging is a fancy term for sun damage. The sun, even with its vitamin D-inducing benefits, can age the skin.

As it does, we are left with wrinkles, spots, reduced skin elasticity, and in severe cases, skin cancer. That is why most anti-aging creams also come with SPF sunscreen as one of their ingredients.

Collagen is another important factor in skin health. Collagen is a structural protein and building block for skin, bones, and more. It acts as a glue, holding things together.

Overtime, collagen production decreases, a loss of elasticity in the skin is one result.

How Do Anti-Aging Creams Work?

The purported benefits of anti-aging creams are nice, but how do they accomplish their goals?

In this case, the two main, active ingredients in Hers’ Anti-Aging Cream is prescription tretinoin and niacinamide, both discussed above.

The effectiveness of anti-aging creams relies entirely on their active ingredients. In addition to the one mentioned above, other ingredients of anti-aging creams include: Glycolic acid, salicylic acid, retinol, and hyaluronic acid.

Studies have shown that these ingredients in combination can be a potent ally in the fight against aging, especially the effects of photodamage.

How Do You Use It?

According to Hers, the prescription-strength anti-aging cream has a tolerance threshold. That means a tolerance must be built up. It is best to follow the recommended application and amount as directed by the medical provider.

Does It Actually Work?

The difficulty in answering this question has to do with the nature of any personalized, prescription medication.

Simply put, it works really well for some people and not others.

Here is one testimonial as to its effects:

“I’ve been using this for about 6 months and have noticed a big difference in my skin. I just turned 34 a s was red my pores to look smaller, even out texture and help with some fine lines. After 6 months I can tell my skin is much smoother under foundation. I rarely get a breakout. I use the higher strength formula and use it every other day and sandwich it between to moisturizers because the active retinol is prescription strength and can be very drying and irritating. It definitely works!!”

  • Alexis, 5/5 Stars on Influenster

Final Thoughts on Hers Prescription Skin Creams

So, do Hers skin care creams work?

Based on the proven ingredients and customer reviews we believe they do.

The beauty of Hers is that you get first-rate professional skin care expertise right from the comfort of your home. 

No product is perfect, but these personalized prescriptions are made to fit your skin, so they may be just right for you.

References, Studies, and Sources:

Skin Care for Women | hers

Healthy Skin | American Skin Association

Consultation for Skin Care | hers

Acne Cream With Tretinoin | Prescription Acne Cream | hers

Tretinoin: A Review of Its Anti-inflammatory Properties in the Treatment of Acne

Niacinamide: A B Vitamin that Improves Aging Facial Skin Appearance

Acne Vulgaris: Treatment Guidelines from the AAD – Practice Guidelines – American Family Physician

Anti-Aging Cream: Custom Prescription Wrinkle Cream | hers

The Tolerability and Efficacy of a Three-product Anti-aging Treatment Regimen in Subjects with Moderate-to-severe Photodamage

How we built this article:

  • Content Process
  • Article History
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Current Version

Researched By

Chris Riley


Edited By

Chris Riley


We are committed to providing our readers with only trusted resources and science-based studies with regards to medication and health information. 

Disclaimer: This general information is not intended to diagnose any medical condition or to replace your healthcare professional. If you suspect medical problems or need medical help or advice, please talk with your healthcare professional.


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