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Pantoprazole Sodium

Pantoprazole Prices, Coupons & Patient Assistance

Generic Protonix

Pantoprazole (Protonix) is an inexpensive drug used to treat gastroesophageal reflux disease, inflammation of the esophagus, and Zollinger-Ellison syndrome. This drug is slightly more popular than comparable drugs. It is available in brand and generic form. Generic pantoprazole is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower. The lowest USARX price for the most common version of pantoprazole is around $2.70, 95% off the average retail price of $66.61.

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Pantoprazole Sodium Side Effects

What should I watch for?

It can take several days before your stomach pain gets better. Check with your doctor or health care professional if your condition does not start to get better, or if it gets worse.

You may need blood work done while you are taking this medicine.

This medicine may cause a decrease in vitamin B12. You should make sure that you get enough vitamin B12 while you are taking this medicine. Discuss the foods you eat and the vitamins you take with your health care professional.

Common and Rare Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Less common

Blurred vision

dry mouth

flushed, dry skin

fruit-like breath odor

increased hunger

increased thirst

increased urination


stomach pain


troubled breathing

unexplained weight loss


Incidence not known

Absence of or decrease in body movements


blistering, peeling, or loosening of the skin


bloody or cloudy urine

bloody, black, or tarry stools

blurred vision


clay-colored stools


continuous ringing or buzzing or other unexplained noise in the ears


dark urine

decreased vision


difficulty with speaking

difficulty with swallowing

dizziness or lightheadedness


fast heartbeat

feeling of constant movement of self or surroundings


general feeling of tiredness or weakness

greatly decreased frequency of urination or amount of urine


hearing loss

high fever

hives, itching, or skin rash


joint pain

large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals

light-colored stools

loss of appetite

mood or mental changes

muscle cramp, pain, or stiffness

muscle spasms (tetany) or twitching

pains in the stomach, side, or abdomen, possibly radiating to the back

pale skin

puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

red skin lesions, often with a purple center

red, irritated eyes


sensation of spinning

sore throat

sores, ulcers, or white spots on the lips or in the mouth

stomach pain, continuing

swelling of the feet or lower legs

swollen glands

tightness in the chest


unexplained bleeding or bruising

unpleasant breath odor

unusual tiredness or weakness

vomiting of blood

yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common


bloated or full feeling

excess air or gas in the stomach or bowels

passing gas

trouble sleeping

Incidence not known

Increased watering of the mouth

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.