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Zylet

Generic Name: loteprednol and tobramycin ophthalmic (LOE te PRED nol and TOE bra MYE sin off THAL mik)
Brand Names: Zylet
Zylet (loteprednol and tobramycin) is used to treat eye inflammation caused by surgery, infection, allergies. Includes Zylet side effects, interactions and indications.
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Drug Information:
Zylet eye drops contain a combination of loteprednol and Tobramycin. Loteprednol is a steroid. It prevents the release of substances in the body that cause inflammation. Tobramycin is an antibiotic that fights bacteria. Zylet eye drops are used to treat eye inflammation caused by surgery, infection, allergies, and other conditions. Zylet may also be used for purposes not listed in this medication guide. You should not use Zylet if you have any type of fungal, viral, or bacterial infection in your eye (including herpes or chickenpox). Learn more

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Zylet Side Effects

Note: This document contains side effect information about loteprednol / tobramycin ophthalmic. Some of the dosage forms listed on this page may not apply to the brand name Zylet.

In Summary

Common side effects of Zylet include: increased intraocular pressure and superficial punctate keratitis. Other side effects include: burning sensation and stinging sensation. See below for a comprehensive list of adverse effects.

For the Consumer

Applies to loteprednol/tobramycin ophthalmic: ophthalmic suspension

Along with its needed effects, loteprednol/tobramycin ophthalmic may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking loteprednol / tobramycin ophthalmic:

More common

  • Blurred vision
  • change in vision
  • feeling like something is in the eye
  • increased intraocular pressure
  • loss of vision
  • pain or irritation of the clear front part of the eye
  • sensitivity of the eyes to light

Less common

  • Blurred vision or seeing blue-green halos around objects
  • decreased vision
  • difficulty seeing at night
  • discharge from the eye
  • dry eyes
  • eyelid burning, redness, itching, pain, or tenderness
  • fast heartbeat
  • fever
  • hives
  • hoarseness
  • irritation and swelling of the eye
  • itching
  • joint pain
  • lid itching and swelling
  • pain in the eye
  • rash
  • redness of the eyelid
  • redness of the skin
  • shortness of breath
  • stiffness or swelling
  • swelling of the eyelids, face, lips, hands, or feet
  • tightness in the chest
  • troubled breathing or swallowing
  • wheezing

Incidence not known

  • Redness of the eye
  • tearing

Some side effects of loteprednol / tobramycin ophthalmic may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Burning of the eye
  • headache
  • increased sensitivity of the eyes to light
  • stinging of the eye

For Healthcare Professionals

Applies to loteprednol / tobramycin ophthalmic: ophthalmic suspension

Ocular

Very common (10% or more): Injection (20%), superficial punctuate keratitis (15%), intraocular pressure increased (10%)

Frequency not reported: Vision disorder, discharge, itching, lacrimation disorder, photophobia, corneal deposit, ocular discomfort, eyelid disorder, unspecified eye disorder

Loteprednol etabonate:

Frequency not reported: Intraocular pressure increased, visual acuity defect, field defect, posterior subcapsular cataract formation, delayed wound healing, secondary ocular infection

Tobramycin:

Frequency not reported: Lid itching, conjunctival erythema, lid swelling

Nervous system

Very common (10% or more): Headache (14%)

Hypersensitivity

Tobramycin:

Frequency not reported: Hypersensitivity

General

The most frequently reported side effects were injections and superficial punctate keratitis, increased intraocular pressure, and burning and stinging upon instillation.

Local

Common (1% to 10%): Burning, stinging

Tobramycin:

Frequency not reported: Localized ocular toxicity

Editorial References and Review

Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.

Source: Drugs.com Zylet (www.drugs.com/zylet.html).