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Zetia

Generic Name: ezetimibe (ez ET i mibe)
Brand Names: Zetia
Zetia (ezetimibe) is used to treat high cholesterol. Includes Zetia side effects, interactions and indications.

Average Savings for ezetimibe (generic): 85.16%
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Drug Information:
Zetia (Ezetimibe) reduces the amount of Cholesterol absorbed by the body. Zetia is used to treat high Cholesterol. Zetia is sometimes given with other Cholesterol-lowering medications. Zetia is only part of a complete program of treatment that also includes diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely. Some Cholesterol medications should not be taken at the same time. If you take Zetia with another Cholesterol medicine, follow your doctor's dosing instructions very carefully. Learn more

Zetia Side Effects

Zetia Side Effects

Note: This document contains side effect information about ezetimibe. Some of the dosage forms listed on this page may not apply to the brand name Zetia.

For the Consumer

Applies to ezetimibe: oral tablet

Along with its needed effects, ezetimibe (the active ingredient contained in Zetia) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Frequency not determined

  • Abdominal fullness
  • black tarry stools
  • bleeding gums
  • bloating
  • blood in urine or stools
  • chills
  • constipation
  • darkened urine
  • fast heartbeat
  • fever
  • gaseous abdominal pain
  • general tiredness or weakness
  • indigestion
  • large, hive-like swelling on face, eyelids, lips, tongue, throat, hands, legs, feet, sex organs
  • loss of appetite
  • light-colored stools
  • muscle cramps or spasms
  • muscular tenderness, wasting or weakness
  • nausea
  • pains in stomach, side or abdomen, possibly radiating to the back
  • pinpoint red spots on skin
  • recurrent fever
  • severe nausea
  • skin rash
  • unusual bleeding or bruising
  • upper right abdominal pain
  • vomiting
  • yellow eyes or skin

Some side effects of ezetimibe may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Fever
  • headache
  • muscle pain
  • runny nose
  • sore throat

Less common

  • Back pain
  • body aches or pain
  • chest pain
  • chills
  • cold or flu-like symptoms
  • congestion
  • coughing
  • diarrhea
  • difficulty in moving
  • dizziness
  • dryness or soreness of throat
  • hoarseness
  • muscle pain or stiffness
  • pain in joints
  • pain or tenderness around eyes and cheekbones
  • shortness of breath or troubled breathing
  • stomach pain
  • stuffy nose
  • tender, swollen glands in neck
  • tightness of chest or wheezing
  • trouble in swallowing
  • unusual tiredness or weakness
  • voice changes

For Healthcare Professionals

Applies to ezetimibe: oral tablet

General

The most frequently reported side effects were upper respiratory tract infection, diarrhea, arthralgia, sinusitis, and pain in extremity.

Gastrointestinal

Common (1% to 10%): Abdominal pain, diarrhea, flatulence

Uncommon (0.1% to 1%): Dyspepsia, gastroesophageal reflux disease, nausea

Postmarketing reports: Pancreatitis, constipation

Immunologic

Postmarketing reports: Anaphylaxis

Musculoskeletal

Common (1% to 10%): Arthralgia, pain in extremity

Uncommon (0.1% to 1%): Muscle spasms, neck pain

Postmarketing reports: Myalgia, myopathy, rhabdomyolysis

Respiratory

Common (1% to 10%): Upper respiratory tract infection, sinusitis

Uncommon (0.1% to 1%): Cough

Postmarketing reports: Dyspnea

Hypersensitivity

Postmarketing reports: Hypersensitivity reaction

Hepatic

Uncommon (0.1% to 1%): Gamma-glutamyltransferase increased, liver function test abnormal, AST/ALT increased

Postmarketing reports: Hepatitis, liver transaminases increased, cholelithiasis, cholecystitis

Hematologic

Postmarketing reports: Thrombocytopenia

Nervous system

Uncommon (0.1% to 1%): Dizziness

Postmarketing reports: Paresthesia, headache

Psychiatric

Postmarketing reports: Depression

Cardiovascular

Uncommon (0.1% to 1%): Hot flush, hypertension

Dermatologic

Postmarketing reports: Angioedema, rash, urticaria, erythema multiforme

Metabolic

Uncommon (0.1% to 1%): Appetite decreased

Other

Common (1% to 10%): Fatigue, influenza

Uncommon (0.1% to 1%): Chest pain, pain, creatine phosphokinase increased

Postmarketing reports: Asthenia

Editorial References and Review

Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.

Source: Drugs.com Zetia (www.drugs.com/zetia.html).