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Zephrex-d

Generic Name: Pseudoephedrine Capsules and Tablets (soo doe e FED rin)
Brand Name: Genaphed, Nasal Decongestant, Nexafed, Psudatabs, Shopko Nasal Decongestant Max, ...show all 10 brand names.
Easy-to-read patient leaflet for Zephrex-D. Includes indications, proper use, special instructions, precautions, and possible side effects.
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Drug Information:
This is not a list of all drugs or health problems that interact with Zephrex-D (pseudoephedrine capsules and tablets). Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Zephrex-D (pseudoephedrine capsules and tablets) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor. Use Zephrex-D (pseudoephedrine capsules and tablets) as ordered by your doctor. Read all information given to you. Follow all instructions closely. Learn more

Zephrex-d Side Effects

Zephrex-D Side Effects

Note: This document contains side effect information about pseudoephedrine. Some of the dosage forms listed on this page may not apply to the brand name Zephrex-D.

For the Consumer

Applies to pseudoephedrine: oral capsule liquid filled, oral liquid, oral solution, oral syrup, oral tablet, oral tablet extended release

Along with its needed effects, pseudoephedrine (the active ingredient contained in Zephrex-D) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur while taking pseudoephedrine:

Rare

- more common with high doses
  • Convulsions (seizures)
  • hallucinations (seeing, hearing, or feeling things that are not there)
  • irregular or slow heartbeat
  • shortness of breath or troubled breathing

Symptoms of overdose

  • Convulsions (seizures)
  • fast breathing
  • hallucinations (seeing, hearing, or feeling things that are not there)
  • increase in blood pressure
  • irregular heartbeat (continuing)
  • shortness of breath or troubled breathing (severe or continuing)
  • slow or fast heartbeat (severe or continuing)
  • unusual nervousness, restlessness, or excitement

Some side effects of pseudoephedrine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Nervousness
  • restlessness
  • trouble in sleeping

Less common

  • Difficult or painful urination
  • dizziness or light-headedness
  • fast or pounding heartbeat
  • headache
  • increased sweating
  • nausea or vomiting
  • trembling
  • unusual paleness
  • weakness

For Healthcare Professionals

Applies to pseudoephedrine: compounding powder, oral capsule, oral liquid, oral suspension extended release, oral tablet, oral tablet chewable, oral tablet extended release

General

The most commonly reported adverse effects have included cardiovascular and (e.g. elevated blood pressure, tachycardia, or arrhythmias), CNS stimulation (e.g. restlessness, insomnia, anxiety, tremors, and rarely hallucinations), skin rashes, and urinary retention.

Cardiovascular

Frequency not reported: Tachycardia, palpitations, arrhythmia, hypertension, impaired circulation to the extremities

Nervous system

Frequency not reported: Headache, tremor

Gastrointestinal

Frequency not reported: Dry mouth, nausea, vomiting

Hypersensitivity

Frequency not reported: Hypersensitivity reactions including cross-sensitivity with other sympathomimetic

Psychiatric

Rare (less than 0.1%): Hallucinations

Frequency not reported: Restlessness, insomnia, sleep disturbances, anxiety, excitability

Genitourinary

Frequency not reported: Urinary retention, especially in men with prostatic enlargement

Ocular

Frequency not reported: Angle-closure glaucoma

Dermatologic

Frequency not reported: Skin rashes, fixed drug eruption in the form of erythematous nodular patches

Other

Post marketing reports: False-positive amphetamine immunoassay

False-positives can occur far below the published threshold indicating that cross-reactivity in human specimens is sometimes greater than the limits reported.

Editorial References and Review

Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.

Source: Drugs.com Zephrex-d (www.drugs.com/cdi/zephrex-d.html).