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Zaleplon

Zaleplon Prescription
Generic Name: zaleplon (ZAH le plon)
Brand Name: Sonata
Physician reviewed zaleplon patient information - includes zaleplon description, dosage and directions.

Average Savings for zaleplon (generic): 67.31%
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Zaleplon Drug Information:

Zaleplon is a sedative that is used to treat insomnia. zaleplon causes relaxation to help you fall asleep and stay asleep. Zaleplon may also be used for purposes not listed in this medication guide. Some people using this medicine have engaged in activity while not fully awake and later had no memory of it. If this happens to you, stop taking zaleplon and call your doctor right away. Serious injury or death could occur if you walk or drive while you are not fully awake. You should not use zaleplon if you are allergic to it, or if you have ever taken sleep medicine and engaged in activity you later don't remember. Learn more

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Zaleplon Side Effects

In Summary

More frequently reported side effects include: amnesia and dizziness. See below for a comprehensive list of adverse effects.

For the Consumer

Applies to zaleplon: oral capsule

Along with its needed effects, zaleplon may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking zaleplon:

Less common

  • Anxiety
  • blurred or double vision
  • not feeling like oneself

Rare

  • Nosebleed
  • seeing, hearing, smelling, or feeling things that are not there

Get emergency help immediately if any of the following symptoms of overdose occur while taking zaleplon:

Symptoms of overdose

  • Confusion
  • clumsiness or unsteadiness, severe
  • dizziness or fainting
  • drowsiness, severe
  • weak muscle tone
  • troubled breathing
  • unusual dullness or feeling sluggish

Some side effects of zaleplon may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Dizziness
  • headache
  • muscle pain
  • nausea

Less common

  • Abdominal pain
  • burning, prickling, or tingling sensation
  • constipation
  • cough
  • difficulty concentrating
  • drowsiness
  • dryness of mouth
  • excess muscle tone
  • eye pain
  • fever
  • heartburn, indigestion, or acid stomach
  • itching
  • itching or burning eyes
  • joint stiffness and/or pain
  • memory loss
  • menstrual pain
  • mental depression
  • nervousness
  • sensitive hearing
  • severe headache
  • shortness of breath
  • skin rash
  • tightness in chest
  • trembling or shaking
  • troubled breathing
  • unusual weakness or tiredness
  • wheezing

After you stop using this medicine, it may still produce some side effects that need attention. During this period of time, check with your doctor immediately if you notice the following side effects:

  • Abdominal and muscle cramps
  • convulsions (seizures)
  • increased sweating
  • sadness
  • trembling or shaking
  • vomiting

For Healthcare Professionals

Applies to zaleplon: oral capsule

General

The most commonly reported side effects included headache, dizziness, nausea, asthenia, and somnolence.

Nervous system

Very common (10% or more): Headache (up to 42%)

Common (1% to 10%): Amnesia, difficulty concentrating, dizziness, hypertonia, hypesthesia, migraine, paresthesia, parosmia, somnolence, taste perversion, tremor, vertigo

Uncommon (0.1% to 1%): Abnormal gait, ataxia, hyperesthesia, hyperkinesia, hypotonia, incoordination, neuralgia, nystagmus

Rare (less than 0.1%): Central nervous system (CNS) stimulation, cerebral ischemia, decreased reflexes, dysarthria, dystonia, facial paralysis, hypokinesia, increased reflexes, myoclonus, neuropathy, slurred speech, stupor, taste loss, visual field defect

Psychiatric

Common (1% to 10%): Abnormal thinking, anxiety, confusion, depersonalization, depression, hallucinations, nervousness

Uncommon (0.1% to 1%): Agitation, apathy, decreased libido, emotional lability, euphoria, insomnia

Rare (less than 0.1%): Bruxism, delusions, hostility, psychomotor retardation, sleep talking, sleep walking

Postmarketing reports: Nightmares

Gastrointestinal

Common (1% to 10%): Abdominal pain, colitis, constipation, dry mouth, dyspepsia, nausea

Uncommon (0.1% to 1%): Circumoral paresthesia, eructation, esophagitis, flatulence, gastritis, gastroenteritis, gingivitis, glossitis, mouth ulceration, rectal hemorrhage, stomatitis

Rare (less than 0.1%): Aphthous stomatitis, cardiospasm, cheilitis, duodenal ulcer, dysphagia, enteritis, gum hemorrhage, increased salivation, intestinal obstruction, peptic ulcer, tongue discoloration, tongue edema, ulcerative stomatitis

Other

Common (1% to 10%): Asthenia, ear pain, fever, hyperacusis, malaise

Uncommon (0.1% to 1%): Chills, face edema, hangover effect, substernal chest pain, tinnitus

Rare (less than 0.1%): Deafness, labyrinthitis

Musculoskeletal

Common (1% to 10%): Arthralgia, arthritis, back pain, myalgia

Uncommon (0.1% to 1%): Arthrosis, bursitis, joint disorder, joint pain, joint stiffness, joint swelling, neck rigidity, myasthenia, tenosynovitis

Rare (less than 0.1%): Myositis, osteoporosis, trismus

Dermatologic

Common (1% to 10%): Photosensitivity reaction, pruritus, rash

Uncommon (0.1% to 1%): Acne, alopecia, contact dermatitis, dry skin, ecchymosis, eczema, maculopapular rash, skin hypertrophy, sweating, urticaria, vesiculobullous rash

Rare (less than 0.1%): Melanosis, psoriasis, purpura, pustular rash, skin discoloration

Ocular

Common (1% to 10%): Abnormal vision, conjunctivitis, eye pain

Uncommon (0.1% to 1%): Diplopia, dry eyes, photophobia, watery eyes

Rare (less than 0.1%): Abnormality of accommodation, blepharitis, cataract specified, corneal erosion, eye hemorrhage, glaucoma, ptosis, retinal detachment

Cardiovascular

Common (1% to 10%): Chest pain, peripheral edema

Uncommon (0.1% to 1%): Angina pectoris, bundle branch block, edema, generalized edema, hypertension, hypotension, palpitation, tachycardia, vasodilation, ventricular extrasystoles

Rare (less than 0.1%): Bigeminy, cyanosis, pericardial effusion, postural hypotension, sinus bradycardia, thrombophlebitis, ventricular tachycardia

Respiratory

Common (1% to 10%): Bronchitis, epistaxis

Uncommon (0.1% to 1%): Asthma, dyspnea, laryngitis, pneumonia, snoring, voice alteration

Rare (less than 0.1%): Apnea, hiccup, hyperventilation, increased sputum, pleural effusion, pulmonary embolus

Genitourinary

Common (1% to 10%): Dysmenorrhea

Uncommon (0.1% to 1%): Bladder pain, breast pain, cystitis, decreased urine stream, dysuria, hematuria, impotence, menorrhagia, metrorrhagia, urinary frequency, urinary incontinence, urinary urgency, vaginitis

Rare (less than 0.1%): Albuminuria, delayed menstrual period, leukorrhea, menopause, urethritis, urinary retention, vaginal hemorrhage

Metabolic

Common (1% to 10%): Anorexia

Uncommon (0.1% to 1%): Gout, hypercholesteremia, increased appetite, thirst, weight gain

Rare (less than 0.1%): Diabetes mellitus, hyperglycemia, hyperuricemia, hypoglycemia, hypoglycemic reaction, ketosis, lactose intolerance, weight loss

Hematologic

Uncommon (0.1% to 1%): Anemia, lymphadenopathy

Rare (less than 0.1%): Eosinophilia, leukocytosis, lymphocytosis

Renal

Uncommon (0.1% to 1%): Kidney calculus, kidney pain

Hepatic

Rare (less than 0.1%): Abnormal liver function tests, bilirubinemia, biliary pain, cholelithiasis, increased ALT, increased AST

Endocrine

Rare (less than 0.1%): Goiter, hypothyroidism

Hypersensitivity

Postmarketing reports: Anaphylactic/anaphylactoid reactions, severe anaphylactic/anaphylactoid reactions

Editorial References and Review

Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.

Source: Drugs.com Zaleplon (www.drugs.com/mtm/zaleplon.html).