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Xopenex

Generic Name: levalbuterol inhalation (leh val BYOO ter all)
Brand Names: Xopenex, Xopenex Concentrate, Xopenex HFA
Xopenex (levalbuterol) is used to treat reversible obstructive airway conditions such as asthma. Includes Xopenex side effects, interactions and indications.

Average Savings for levalbuterol hydrochlorid (generic): 61.8%
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Drug Information:
Xopenex (Levalbuterol) is a short-acting bronchodilator that relaxes muscles in the airways and increases air flow to the lungs. Xopenex inhalation is used to treat or prevent bronchospasm in people with reversible obstructive airway disease. Xopenex solution is for use in adults and children 6 years of age and older. Xopenex Hfa aerosol is for use in adults and children 4 years of age and older. You should not use Xopenex if you are allergic to Levalbuterol or albuterol (Accuneb, ProAir, Proventil, Ventolin). Learn more

Xopenex Side Effects

Xopenex Side Effects

Note: This document contains side effect information about levalbuterol. Some of the dosage forms listed on this page may not apply to the brand name Xopenex.

In Summary

Common side effects of Xopenex include: rhinitis. Other side effects include: nervousness and tremor. See below for a comprehensive list of adverse effects.

For the Consumer

Applies to levalbuterol: inhalation aerosol powder, inhalation solution

Along with its needed effects, levalbuterol (the active ingredient contained in Xopenex) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking levalbuterol:

More common

  • Fast heartbeat

Less common or rare

  • Chest pain or tightness
  • dizziness
  • feeling “faint”
  • lightheadedness
  • troubled breathing

Incidence not known

  • Cough
  • difficult or labored breathing
  • difficulty swallowing
  • extra heartbeats
  • fainting
  • fast, pounding, slow, or irregular heartbeat or pulse
  • hives, welts, itching, or rash
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • noisy breathing
  • redness of the skin
  • tightness in the chest
  • unusual tiredness or weakness

Get emergency help immediately if any of the following symptoms of overdose occur while taking levalbuterol:

Symptoms of overdose

  • Chest pain
  • dizziness
  • dry mouth
  • general feeling of discomfort or illness
  • headache
  • impaired consciousness
  • irregular or fast heartbeat
  • lightheadedness
  • nausea
  • nervousness
  • seizures
  • sleeplessness
  • sweating
  • tremor

Some side effects of levalbuterol may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Accidental injury (in children 4 to 11 years of age)
  • anxiety
  • body aches or pain
  • chills
  • congestion
  • cough or hoarseness
  • dryness or soreness of the throat
  • fever
  • general aches and pains
  • headache
  • hoarseness
  • increased cough
  • leg cramps
  • loss of appetite
  • migraines or other headaches
  • muscle tightness
  • nervousness
  • runny or stuffy nose

Less common or rare

  • Abdominal or stomach pain
  • abnormal growth filled with fluid or semisolid material
  • blemishes on the skin
  • blood in the urine
  • bloody nose
  • burning, dry, or itching eyes
  • burning or stinging of the skin
  • cough producing mucus
  • cramps
  • diarrhea
  • difficulty having a bowel movement (stool)
  • discharge from the eye
  • dry mouth or throat
  • ear pain
  • excessive tearing
  • eye itch
  • heavy menstrual bleeding
  • muscle pain
  • night sweats
  • numbness or decreased sensitivity of the hand
  • pain
  • painful cold sores or blisters on the lips, nose, eyes, or genitals
  • pimples
  • redness, pain, or swelling of the eye, eyelid, or inner lining of the eyelid
  • tingling sensation in the arms or legs
  • vaginal yeast infection
  • weight loss

For Healthcare Professionals

Applies to levalbuterol: inhalation aerosol, inhalation solution

General

This drug has been associated with paradoxical bronchospasm, cardiovascular effects, immediate hypersensitivity reactions, and hypokalemia.

Cardiovascular

ECG abnormal, ECG change, hypotension, and syncope occurred in less than 2%.

Common (1% to 10%): Hypertension, tachycardia

Frequency not reported: ECG abnormal, ECG change, hypotension, syncope

Postmarketing reports: Arrhythmias (including atrial fibrillation, supraventricular tachycardia, extrasystoles)

Musculoskeletal

Myalgia occurred in less than 2%.

Common (1% to 10%): Leg cramps

Frequency not reported: Myalgia

Metabolic

Metabolic acidosis occurred in less than 2%.

Frequency not reported: Changes in plasma glucose and serum potassium; metabolic acidosis

Nervous system

Central nervous system stimulation and hyperesthesia of the hand occurred in less than 2%.

Common (1% to 10%): Dizziness, migraine, tremor, nervousness

Frequency not reported: Central nervous system stimulation, hyperesthesia of the hand

Other

Common (1% to 10%): Pain, flu syndrome, accidental injury, asthenia, fever

Frequency not reported: Ear pain, herpes simplex, chills, cyst

Ear pain, herpes simplex, chills, and cyst occurred in less than 2%.

Gastrointestinal

Diarrhea, dry mouth, dry throat, nausea, gastroenteritis, vomiting, and constipation occurred in less than 2%.

Common (1% to 10%): Dyspepsia

Frequency not reported: Diarrhea, dry mouth, dry throat, nausea, gastroenteritis, vomiting, constipation

Postmarketing reports: Gastroesophageal reflux disease (GERD), nausea

Respiratory

Common (1% to 10%): Asthma, pharyngitis, rhinitis, bronchitis, sinusitis, turbinate edema, cough increased, viral infection

Frequency not reported: Epistaxis, lung disorder, asthma exacerbation, wheezing

Postmarketing reports: Chest pain, dysphonia, dyspnea

Viral infection, epistaxis, lung disorder, asthma exacerbation, and wheezing occurred in less than 2%.

Dermatologic

Frequency not reported: Acne, sweating

Postmarketing reports: Rash, urticaria

Acne and sweating occurred less than 2%.

Hypersensitivity

Common (1% to 10%): Allergic reactions

Postmarketing reports: Angioedema, anaphylaxis

Genitourinary

Frequency not reported: Hematuria, dysmenorrhea, vaginal moniliasis

Hematuria, dysmenorrhea, vaginal moniliasis occurred in less than 2%.

Immunologic

Frequency not reported: Lymphadenopathy

Lymphadenopathy occurred in less than 2%.

Ocular

Eye itch occurred in less than 2%.

Frequency not reported: Eye itch

Psychiatric

Insomnia occurred in less than 2%.

Common (1% to 10%): Anxiety

Frequency not reported: Insomnia

Editorial References and Review

Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.

Source: Drugs.com Xopenex (www.drugs.com/xopenex.html).