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Warfarin sodium

Generic Name: warfarin (oral) (WAR far in)
Brand Names: Coumadin, Jantoven
Warfarin is an anticoagulant used to prevent heart attacks, strokes, and blood clots. Learn about side effects, interactions and indications.

Average Savings for warfarin sodium (generic): 24.67%
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Drug Information:
Warfarin is an anticoagulant (blood thinner). Warfarin reduces the formation of blood clots. Warfarin is used to treat or prevent blood clots in veins or arteries, which can reduce the risk of stroke, heart attack, or other serious conditions. Warfarin may also be used for purposes not listed in this medication guide. You should not take warfarin if you are prone to bleeding because of a medical condition, if you have an upcoming surgery, or if you need a spinal tap or epidural. Do not take warfarin if you cannot take it on time every day. Learn more

Warfarin sodium Side Effects

Warfarin Side Effects

For the Consumer

Applies to warfarin: oral tablet

Warning

Oral route (Tablet)

Warfarin can cause major or fatal bleeding. Regular monitoring of INR should be performed on all treated patients. Drugs, dietary changes, and other factors affect INR levels achieved with warfarin sodium therapy. Instruct patients about prevention measures to minimize risk of bleeding and to report signs and symptoms of bleeding.

Along with its needed effects, warfarin may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking warfarin:

Less common

  • Bleeding gums
  • blood in the urine
  • bloody stools
  • blurred vision
  • burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  • chest pain or discomfort
  • confusion
  • coughing up blood
  • difficulty with breathing or swallowing
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • excessive bruising
  • headache
  • increased menstrual flow or vaginal bleeding
  • nosebleeds
  • paralysis
  • peeling of the skin
  • prolonged bleeding from cuts
  • red or black, tarry stools
  • red or dark brown urine
  • stomach pain with cramping
  • sweating
  • unexplained swelling
  • unusual tiredness or weakness

Rare

  • Arm, back, or jaw pain
  • blue-green to black skin discoloration
  • blue or purple toes
  • change in consciousness
  • chest tightness or heaviness
  • chills
  • clay-colored stools
  • diarrhea
  • dizziness
  • fainting or loss of consciousness
  • fast or irregular breathing
  • fast or irregular heartbeat
  • fever
  • itching or skin rash
  • light-colored stools
  • loss of appetite
  • nausea and vomiting
  • pain in the toes
  • pain, redness, or sloughing of the skin
  • pale skin
  • purplish red, net-like, blotchy spots on the skin
  • skin blisters
  • small red or purple spots on the skin
  • stomach pain
  • swelling of the eyes or eyelids
  • troubled breathing with exertion
  • unpleasant breath odor
  • unusual bleeding or bruising
  • upper right stomach pain
  • vomiting of blood
  • yellow eyes and skin

Some side effects of warfarin may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

  • Joint pain
  • muscle pain

Rare

  • Bloated
  • change in taste, or bad, unusual, or unpleasant (after) taste
  • cold intolerance
  • excess air or gas in the stomach or intestines
  • full feeling
  • general feeling of discomfort or illness
  • hair loss or thinning of the hair
  • hives or welts
  • lack or loss of strength
  • pain
  • passing gas
  • red, sore, or itching skin
  • sores, welting, or blisters
  • unusual drowsiness, dullness, or feeling of sluggishness

For Healthcare Professionals

Applies to warfarin: compounding powder, intravenous powder for injection, oral tablet

General

The most common adverse reactions were fatal and nonfatal hemorrhage from any tissue or organ.

Cardiovascular

Frequency not reported: Hemorrhage, purple toes syndrome, infarction, systemic cholesterol microembolization, vasculitis, systemic atheroemboli

Nervous system

Frequency not reported: Cerebral hemorrhage, cerebral subdural hematoma, lethargy, headache, dizziness, taste perversion, paresthesia

Gastrointestinal

Frequency not reported: Gastrointestinal hemorrhage, rectal hemorrhage, hematemesis, pancreatitis, diarrhea, nausea, vomiting, melena, abdominal pain, cramping, flatulence, bloating

Dermatologic

Frequency not reported: Rash, alopecia, purpura, erythematous swollen skin patches, ecchymosis, skin necrosis, dermatitis, bullous eruptions, urticaria, pruritus

Musculoskeletal

Frequency not reported: Tissue necrosis, chills

Metabolic

Frequency not reported: Calciphylaxis, edema

Respiratory

Frequency not reported: Hemothorax, epistaxis, tracheal or tracheobronchial calcification

Genitourinary

Frequency not reported: Hematuria

Hematologic

Frequency not reported: Unexplained decrease in hematocrit, hemoglobin decreased

Hepatic

Frequency not reported: Jaundice, hepatic dysfunction, hepatitis, cholestatic hepatic injury, liver enzymes elevated

Immunologic

Frequency not reported: Hypersensitivity, allergic reactions, anaphylactic reactions

Other

Frequency not reported: Fever, fatigue, malaise, asthenia, pain, cold intolerance, feeling cold

Editorial References and Review

Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.

Source: Drugs.com Warfarin Sodium (www.drugs.com/warfarin.html).