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Vivelle-dot

Vivelle-dot Prescription
Generic Name: estradiol transdermal (ES tra DYE ole tranz DERM al)
Brand Name: Alora, Climara, Estradiol Patch, Menostar, Minivelle, Vivelle-Dot
Physician reviewed Vivelle-Dot patient information - includes Vivelle-Dot description, dosage and directions.

Average Savings for estradiol (generic): 41.91%
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Vivelle-dot Coupons & Prices

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Vivelle-dot Drug Information:

Estradiol is a form of estrogen, a female sex hormone produced by the ovaries. Estrogen is necessary for many processes in the body. Vivelle-Dot skin patches are used to treat certain symptoms of menopause such as hot flashes, and vaginal dryness, burning, and irritation. Vivelle-Dot is also used to prevent postmenopausal osteoporosis, or to treat ovarian disorders. Vivelle-Dot may also be used for purposes not listed in this medication guide. You should not use Estradiol if you have: undiagnosed vaginal bleeding, liver disease, coronary artery disease, if you will have major surgery, or if you have ever had a heart attack, a stroke, a blood clot, or cancer of the breast, uterus/cervix, or vagina. Learn more

Buy Vivelle-dot Online and Vivelle-dot Delivery

USARx offers the following ways to purchase this medication. Choose the Best option for you!

  • Guaranteed Price

    Local Pharmacy Pickup of Vivelle-dot

    Pay this amount and pick up your prescription at ANY Retail pharmacy of your choice! Walgreens, CVS, Walmart, etc.

  • 30-day supply
    90-day supply

    Mail Order Home Delivery of Vivelle-dot

    The easiest way to receive your medications.

Vivelle-dot Side Effects

Note: This document contains side effect information about estradiol. Some of the dosage forms listed on this page may not apply to the brand name Vivelle-Dot.

In Summary

Common side effects of Vivelle-Dot include: headache. Other side effects include: limb pain. See below for a comprehensive list of adverse effects.

For the Consumer

Applies to estradiol: vaginal capsule liquid filled, vaginal cream, vaginal insert extended release, vaginal tablet

Other dosage forms:

  • transdermal gel/jelly, transdermal patch extended release, transdermal spray
Warning

Vaginal route (Insert, Extended Release; Cream)

Estrogens increase the risk of endometrial cancer; monitor for abnormal vaginal bleeding. Estrogens with or without progestins should not be used for the prevention of cardiovascular disease or dementia. Increased risks of myocardial infarction, stroke, invasive breast cancer, pulmonary emboli, and deep vein thrombosis in postmenopausal women (50 to 79 years of age) have been reported. An increased risk of developing probable dementia in postmenopausal women 65 years of age or older has also been reported in women receiving estrogen alone or estrogen combined with progestins. Risks should be assumed to be similar for other doses, combinations, and dosage forms of estrogens and progestins. Estrogens, with or without progestins, should be prescribed at the lowest effective doses and for the shortest duration possible.

Vaginal route (Insert, Extended Release)

Use of unopposed estrogens increases the risk of endometrial cancer, while addition of a progestin decreases the risk of endometrial hyperplasia. Rule out malignancy if abnormal vaginal bleeding develops. Do not use estrogen alone or in combination with progestin to prevent cardiovascular disease or dementia. There is an increased risk of cardiovascular disorders (ie, DVT, pulmonary embolism, stroke, myocardial infarction) with combination therapy in women 50 years or older, and an increased risk of dementia in women 65 years or older with estrogen monotherapy or combination therapy. Combination therapy also increases the risk of invasive breast cancer. Prescribe estrogens with or without progestins at the lowest effective dose and for the shortest duration consistent with risks and treatment goals.

Along with its needed effects, estradiol (the active ingredient contained in Vivelle-Dot) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking estradiol:

Less common

  • Vaginal yeast infection

Incidence not known

  • Change in vaginal discharge
  • clear or bloody discharge from the nipple
  • decrease in the amount of urine
  • dimpling of the breast skin
  • fast heartbeat
  • fever
  • hives, itching, or rash
  • hoarseness
  • inverted nipple
  • irritation
  • joint pain, stiffness, or swelling
  • lump in the breast or under the arm
  • noisy, rattling breathing
  • pain or feeling of pressure in the pelvis
  • pain, redness, or swelling in the arm or leg
  • persistent crusting or scaling of the nipple
  • redness of the skin
  • redness or swelling of the breast
  • sore on the skin of the breast that does not heal
  • swelling of the eyelids, face, fingers, lips, hands, feet, or lower legs
  • tightness in the chest
  • troubled breathing at rest
  • troubled breathing or swallowing
  • vaginal bleeding

Get emergency help immediately if any of the following symptoms of overdose occur while taking estradiol:

Symptoms of overdose

  • Dizziness
  • drowsiness
  • nausea
  • stomach pain
  • tenderness of the breasts
  • unusual tiredness or weakness
  • vomiting

Some side effects of estradiol may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Back pain
  • headache
  • itching or pain of the vagina or genital area
  • thick, white vaginal discharge with mild or no odor
  • weight gain

Less common

  • Body aches or pain
  • chills
  • cough
  • diarrhea
  • ear congestion
  • loss of voice
  • nasal congestion
  • runny nose
  • sneezing
  • sore throat

Incidence not known

  • Feeling sad or empty
  • headache, severe and throbbing
  • irritability
  • lack of appetite
  • tiredness
  • trouble concentrating
  • trouble sleeping
  • welts

For Healthcare Professionals

Applies to estradiol: compounding powder, intramuscular solution, oral tablet, transdermal emulsion, transdermal film extended release, transdermal gel, transdermal spray, vaginal ring

Genitourinary

Very common (10% or more): Breast pain (29%)

Common (1% to 10%): Vulvovaginal pruritus, leukorrhea, vaginal hemorrhage, vaginal discharge, vaginal discomfort, menopause symptoms, breakthrough bleeding or spotting, dysmenorrhea, breast swelling, menorrhagia, metrorrhagia, endometrial hyperplasia

Uncommon (0.1% to 1%): Urinary problems

Rare (less than 0.1%): Galactorrhea

Postmarketing reports: Vaginal irritation, vaginal pain, genital pruritus, changes in bleeding pattern, pelvic pain, breast tenderness, vaginal ulceration, uterine fibroids

Gastrointestinal

Very common (10% or more): Abdominal pain (16%),

Common (1% to 10%): Flatulence, nausea, diarrhea

Uncommon (0.1% to 1%): Vomiting

Postmarketing reports: Abdominal distension

Musculoskeletal

Very common (10% or more): Back pain (11%), arthralgia (11%)

Common (1% to 10%): Leg cramps

Cardiovascular

Common (1% to 10%): Varicose veins, cardiac symptoms (e.g. palpitations)

Uncommon (0.1% to 1%): Hot flush, hypertension, venous thromboembolic disease

Rare (less than 0.1%): Arterial hypertension

Postmarketing reports: Deep vein thrombosis, changes in blood pressure

Nervous system

Very common (10% or more): Headache (18%)

Uncommon (0.1% to 1%): Vertigo, migraine

Rare (less than 0.1%): Aggravation of epilepsy

Postmarketing reports: Migraine aggravated, paresthesia, dizziness

Oncologic

Uncommon (0.1% to 1%): Benign breast neoplasm, increased volume of uterine leiomyoma

Postmarketing reports: Endometrial cancer, breast cancer

Other

Very common (10% or more): Pain (11%)

Common (1% to 10%): Edema

Uncommon (0.1% to 1%): Weight increased, asthenia

Postmarketing reports: Drug ineffectiveness, blood estrogen increase, fatigue, exacerbation of hereditary angioedema

Psychiatric

Common (1% to 10%): Depression

Uncommon (0.1% to 1%): Sleep disorders, nervousness, mood swings

Rare (less than 0.1%): Change in libido

Postmarketing reports: Vaginismus, insomnia, anxiety, irritability

Dermatologic

Common (1% to 10%): Pruritus

Uncommon (0.1% to 1%): Rash

Rare (less than 0.1%): Skin discoloration, acne

Postmarketing reports: Urticaria, erythematous or pruritic rash, alopecia, hyperhidrosis, night sweats, contact dermatitis, eczema

Ocular

Uncommon (0.1% to 1%): Vision abnormal NOS

Postmarketing reports: Visual disturbances, contact lens intolerance

Hepatic

Rare (less than 0.1%): Liver function tests abnormalities

Postmarketing reports: Cholestatic jaundice

Metabolic

Rare (less than 0.1%): Glucose intolerance

Postmarketing reports: Fluid retention

Hypersensitivity

Rare (less than 0.1%): Anaphylactic reaction (with a past history of allergic reaction)

Postmarketing reports: Anaphylactic reactions, hypersensitivity

Immunologic

Very common (10% or more): Upper respiratory tract infection (17%)

Common (1% to 10%): Vulvovaginal mycotic infection, pharyngitis, rhinitis, sinusitis, moniliasis genital

Uncommon (0.1% to 1%): Vaginitis/vaginal candidosis

Local

Common (1% to 10%): Skin irritation (topical gel)

Postmarketing reports: Application site reaction

Editorial References and Review

Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.

Source: Drugs.com Vivelle-dot (www.drugs.com/mtm/vivelle-dot.html).

What pharmacies accept this discount program?

Rite Aid, Walmart, Walgreens, CVS, Duane Reade, Target, K-mart, and all national and regional chains accept the card.

What if you didn’t find your pharmacy names above?

Search our pharmacy network on our homepage and medication search results.

What if the pharmacist refuses to take the card?

If they are in the participating network, they legally have to accept and process the card, as long as you have a valid Vivelle-Dot prescription. If they need help in processing the card, have them call the support phone number or email us directly.

What if the dosage, quantity, or drug name of the Vivelle-Dot coupon I downloaded is different from what I’m trying to fill right now?

Any coupon can be applied to any prescription drug at a participating pharmacy and receive a discount. Prescription prices are subject to change.

Does this coupon work for brand name drug and the generic version of Vivelle-Dot?

Yes, both generic and brand prescription medication are covered by the coupon, as long as you have a valid Vivelle-Dot prescription.

Does this free coupon work with federal insurance plans, like Medicare? What about commercial insurance?

No, you must decide at the pharmacy either to use your free Vivelle-Dot coupon or your insurance. 

Are there eligibility requirements for using USA Rx?

No, unlike some different discount cards, USA Rx does not have eligibility requirements.

Vivelle dot Prescription Savings Explained

FAQ Disclaimer: USA Rx LLC has a full endorsement of our prescription savings discount program. This product does not replace your insurance plan. You may check the price of both your insurance plan (copay) and our patient assistance program. That is an easy step to get the lowest price on your prescriptions. Our affiliates use the “powered by USA Rx” symbol in marketing materials. If you have a medical condition and need assistance with figuring out your best option is for a discount program of prescription savings, please give us a call or drop us an email. If you need medical help, please seek proper medical care as soon as possible. Chat with your doctor or pharmacist about all possible side effects, which may include swelling of the ankles or feet, dark urine, and breast lumps. You should follow your dosage schedule carefully and replace the patch at a regular time. All cardholders adhere to our privacy policy and we use recent information to create our pricing estimates, which are subject to change. Prescription prices are subject to change.