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Vistaril

Generic Name: hydroxyzine (hye DROX ee zeen)
Brand Names: Vistaril
Vistaril (hydroxyzine) is used as a sedative to treat anxiety and tension and to treat allergic skin reactions. Includes Vistaril side effects. interactions and indications.

Average Savings for hydroxyzine pamoate (generic): 29.93%
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Drug Information:
Vistaril (hydroxyzine) reduces activity in the central nervous system. It also acts as an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of itching, or hives on the skin. Vistaril is used as a sedative to treat anxiety and tension. It is also used together with other medications given during and after general anesthesia. Vistaril is also used to treat allergic skin Reactions such as hives or contact dermatitis. You should not use Vistaril if you are pregnant, especially during the first or second trimester. Learn more

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Vistaril Side Effects

Note: This document contains side effect information about hydroxyzine. Some of the dosage forms listed on this page may not apply to the brand name Vistaril.

For the Consumer

Applies to hydroxyzine: oral capsule, oral syrup, oral tablet

Other dosage forms:

  • intramuscular solution

Along with its needed effects, hydroxyzine (the active ingredient contained in Vistaril) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking hydroxyzine:

Incidence not known

  • Chest pain or discomfort
  • cough
  • difficulty with swallowing
  • dizziness
  • fainting
  • fast heartbeat
  • hives, itching, or skin rash
  • irregular or slow heart rate
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • shortness of breath
  • tightness in the chest
  • unusual tiredness or weakness

Get emergency help immediately if any of the following symptoms of overdose occur while taking hydroxyzine:

Symptoms of overdose

  • Decreased awareness or responsiveness
  • drowsiness
  • nausea
  • seizures
  • severe sleepiness
  • vomiting

Some side effects of hydroxyzine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Rare

  • Shakiness in the legs, arms, hands, or feet
  • trembling or shaking of the hands or feet

Incidence not known

  • Dry mouth
  • headache
  • seeing, hearing, or feeling things that are not there

For Healthcare Professionals

Applies to hydroxyzine: compounding powder, intramuscular solution, oral capsule, oral suspension, oral syrup, oral tablet

General

The most commonly reported side effects included sleepiness, headache, and tiredness.

Nervous system

Very common (10% or more): Sleepiness (up to 13.74%)

Common (1% to 10%): Headache

Rare (0.01% to 0.1%): Convulsion, tremor

Frequency not reported: Anticholinergic activity, central nervous system (CNS) depression, drowsiness, incoordination, involuntary motor activity, psychomotor impairment, stimulation

Postmarketing reports: Dizziness, dyskinesia, dystonia, paresthesia, sedation, seizures, syncope

Other

Common (1% to 10%): Tiredness

Frequency not reported: Antimuscarinic effects, lassitude

Postmarketing reports: Asthenia, malaise, pyrexia, sudden death

Gastrointestinal

Common (1% to 10%): Dry mouth

Postmarketing reports: Constipation, diarrhea, nausea, vomiting

Cardiovascular

Frequency not reported: QT prolongation, Torsade de Pointes

Postmarketing reports: Cardiac arrest, cardiac arrhythmias, edema, hypotension, ventricular arrhythmias, ventricular fibrillation, ventricular tachycardia

Hypersensitivity

Frequency not reported: Hypersensitivity reaction

Postmarketing reports: Allergic reaction, anaphylactic shock, angioedema, hypersensitivity

Respiratory

Frequency not reported: Respiratory depression

Postmarketing reports: Bronchospasm

Dermatologic

Postmarketing reports: Acute generalized exanthematous pustulosis (AGEP), bullous condition (pemphigoids, toxic epidermal necrolysis), dermatitis, erythema, erythema multiforme, fixed drug eruptions, increased sweating, maculopapular rash, pruritus, rash, Stevens-Johnson syndrome, urticaria

Psychiatric

Postmarketing reports: Aggression, agitation, confusion, depression, disorientation, hallucination, insomnia, tics

Genitourinary

Postmarketing reports: Dysuria, enuresis, urinary retention

Ocular

Postmarketing reports: Accommodation disorder, blurred vision, oculogyric crisis

Hepatic

Postmarketing reports: Hepatitis, liver function tests abnormal

Hematologic

Postmarketing reports: Thrombocytopenia

Metabolic

Postmarketing reports: Weight gain

Editorial References and Review

Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.

Source: Drugs.com Vistaril (www.drugs.com/vistaril.html).