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Vardenafil relaxes muscles of the blood vessels and increases blood flow to particular areas of the body.
Vardenafil is used to treat erectile dysfunction (impotence).
Vardenafil may also be used for purposes not listed in this medication guide.
Some medicines can cause unwanted or dangerous effects when used with vardenafil. Tell your doctor about all your medicines, especially riociguat (Adempas).
Do not take vardenafil if you are also using a nitrate drug for chest pain or heart problems, including nitroglycerin, isosorbide dinitrate, isosorbide mononitrate, and some recreational drugs such as "poppers". Taking vardenafil with a nitrate medicine can cause a sudden and serious decrease in blood pressure.
Contact your doctor or seek emergency medical attention if your erection is painful or lasts longer than 4 hours. A prolonged erection (priapism) can damage the penis.
Stop using vardenafil and get emergency medical help if you have sudden vision loss.
You should not use vardenafil if you are allergic to it, or if you take other medicines to treat pulmonary arterial hypertension, such as riociguat (Adempas).
Vardenafil is not approved for men younger than 18 years old.
Do not take vardenafil if you are also using a nitrate drug for chest pain or heart problems. This includes nitroglycerin, isosorbide dinitrate, and isosorbide mononitrate. Nitrates are also found in some recreational drugs such as amyl nitrate or nitrite ("poppers"). Taking vardenafil with a nitrate medicine can cause a sudden and serious decrease in blood pressure.
Tell your doctor if you have ever had:
heart disease, heart rhythm problems;
a heart attack, stroke, or congestive heart failure;
long QT syndrome (in you or a family member);
high or low blood pressure;
seizures;
liver disease, kidney disease (or if you are on dialysis);
a blood cell disorder such as sickle cell anemia, multiple myeloma, or leukemia;
a bleeding disorder such as hemophilia;
a stomach ulcer;
hearing or vision problems, vision loss;
an eye disorder such as retinitis pigmentosa (an inherited condition of the eye);
a physical deformity of the penis (such as Peyronie's disease); or
if you have been told you should not have sexual intercourse for health reasons.
Vardenafil can decrease blood flow to the optic nerve of the eye, causing sudden vision loss. This has occurred in a small number of people, most of whom also had heart disease, diabetes, high blood pressure, high cholesterol, or certain pre-existing eye problems, and in those who smoked or were over 50 years old. It is not clear whether vardenafil is the actual cause of vision loss.
Staxyn may contain phenylalanine. Talk to your doctor before using this form of vardenafil if you have phenylketonuria (PKU).
Vardenafil is not for use in women, and the effects of vardenafil during pregnancy or in breastfeeding women are unknown.
Staxyn (vardenafil disintegrating tablets) should not be used in place of Levitra (vardenafil regular tablets). Avoid medication errors by using only the form and strength your doctor prescribes.
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
Vardenafil can be taken with or without food.
Remove an orally disintegrating (Staxyn) tablet from the package only when you are ready to take the medicine. Place the tablet in your mouth and allow it to dissolve without chewing. Swallow several times as the tablet dissolves. Do not take Staxyn with liquid.
Vardenafil is taken only when needed, about 60 minutes before sexual activity. The medicine can help achieve an erection when sexual stimulation occurs. An erection will not occur just by taking a pill.
Contact your doctor or seek emergency medical attention if your erection is painful or lasts longer than 4 hours. A prolonged erection (priapism) can damage the penis.
Store at room temperature away from moisture and heat.
If you receive medical care for heart problems, tell your caregivers when you last took vardenafil.
Since vardenafil is used as needed, you are not likely to be on a dosing schedule.
Do not take vardenafil more than once a day. Allow 24 hours to pass between doses.
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Grapefruit may interact with vardenafil and lead to unwanted side effects. Avoid the use of grapefruit products.
Drinking alcohol can increase certain side effects of vardenafil.
Do not use any other drug to treat impotence unless your doctor tells you to.
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop taking vardenafil and get emergency medical help if you have:
heart attack symptoms--chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating;
vision changes or sudden vision loss; or
erection is painful or lasts longer than 4 hours (prolonged erection can damage the penis).
Stop using vardenafil and call your doctor at once if you have:
ringing in your ears, or sudden hearing loss;
irregular heartbeat;
swelling in your hands, ankles, or feet;
shortness of breath;
a light-headed feeling, like you might pass out;
penis erection that is painful or lasts 4 hours or longer; or
seizure (convulsions).
Common side effects may include:
flushing (warmth, redness, or tingly feeling);
stuffy nose, sinus pain;
headache, dizziness;
upset stomach; or
back pain.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Usual Adult Dose for Erectile Dysfunction:
-Initial dose: 10 mg orally once a day, as needed, approximately 60 minutes before sexual activity. Increase to 20 mg or decrease to 5 mg based on efficacy and tolerability.
-Maximum dose: 20 mg once a day
Patients on stable alpha blocker therapy:
-Initial dose: 5 mg orally once a day
Comments:
-Sexual stimulation is required for a response to treatment.
-A time interval between dosing should be considered when administering this drug concomitantly with alpha-blockers.
-Patients taking alpha-blockers should not initiate vardenafil therapy with the orally disintegrating tablet.
Use: Erectile dysfunction
Usual Geriatric Dose for Erectile Dysfunction:
65 years or older:
-Initial dose: 5 mg orally once a day, as needed, approximately 60 minutes before sexual activity
Comments: Sexual stimulation is required for a response to treatment.
Use: Erectile dysfunction
Do not take vardenafil with similar medications such as avanafil (Stendra), sildenafil (Viagra), or tadalafil (Cialis). Tell your doctor about all other medications you use for erectile dysfunction.
Tell your doctor about all your other medicines, especially:
an antibiotic--clarithromycin, erythromycin;
antifungal medicine--itraconazole, ketoconazole;
drugs to treat high blood pressure or a prostate disorder--alfuzosin, doxazosin, prazosin, silodosin, terazosin, tamsulosin;
heart rhythm medicine--amiodarone, dronedarone, procainamide, quinidine, sotalol; or
HIV/AIDS medicine--atazanavir, indinavir, ritonavir, saquinavir, and others.
This list is not complete and many other drugs may affect vardenafil. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
Further informationRemember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.
Source: Drugs.com Vardenafil Hydrochloride (www.drugs.com/vardenafil.html).
Commonly reported side effects of vardenafil include: headache and flushing. Other side effects include: dyspepsia and rhinitis. See below for a comprehensive list of adverse effects.
For the ConsumerApplies to vardenafil: oral tablet, oral tablet disintegrating
Along with its needed effects, vardenafil may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking vardenafil:
Less common
Incidence not known
Some side effects of vardenafil may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
Less common
For Healthcare Professionals
Applies to vardenafil: oral tablet, oral tablet disintegrating
GeneralThe most commonly reported adverse reaction is headache.
CardiovascularVery common (10% or more): Flushing (11%)
Common (1% to 10%): Palpitation, tachycardia, angina pectoris, myocardial infarction, ventricular tachyarrhythmias, hypotension
Rare (less than 0.1%): Hypertension
Postmarketing reports: Serious cerebrovascular hemorrhage, sudden cardiac death, transient ischemic attack, unstable angina and ventricular arrhythmia have been reported in temporal association with another medicinal product in this class.
Nervous systemVery common (10% or more): Headache (15%)
Common (1% to 10%): Dizziness, paresthesia and dysesthesia, somnolence, sleep disorder, syncope, amnesia, seizure
Postmarketing reports: Seizure, seizure recurrence, transient global amnesia
DermatologicCommon (1% to 10%): Erythema, rash, angioedema, allergic edema
Rare (less than 0.1%): Photosensitivity reaction
GastrointestinalCommon (1% to 10%): Dyspepsia, nausea, gastrointestinal and abdominal pain, dry mouth, diarrhea, gastroesophageal reflux disease, gastritis, vomiting
GenitourinaryUncommon (0.1% to 1%): Increase in erection
Rare (less than 0.1%): Priapism
Postmarketing reports: Penile hemorrhage, hematospermia
HepaticCommon (1% to 10%): Increase in transaminases
Rare (less than 0.1%) Increase in gamma-glutamyl-transferase
HypersensitivityCommon (1% to 10%): Allergic reactions
MusculoskeletalCommon (1% to 10%): Back pain, increase in creatine phosphokinase (CPK), increased muscle tone and cramping, myalgia
OcularCommon (1% to 10%): Visual disturbance, ocular hyperemia, visual color distortions, eye pain and eye discomfort, photophobia, increase in intraocular pressure, conjunctivitis
Rare (less than 0.1%): Increased lacrimation
Postmarketing reports: Non-arteritic anterior ischemic optic neuropathy (NAION), visual disturbances including vision loss (temporary or permanent), such as visual field defect, retinal vein occlusion, and reduced visual acuity.
Non-arteritic anterior ischemic optic neuropathy (NAION), a cause of decreased vision including permanent loss of vision, has been reported rarely postmarketing in temporal association with the use of phosphodiesterase type 5 (PDE5) inhibitors, including vardenafil.
OtherCommon (1% to 10%): Accidental injury, flu syndrome, tinnitus, vertigo, chest pain, feeling unwell
Postmarketing reports: Cases of sudden decrease or loss of hearing in temporal association with the use of PDE5 inhibitors, including this drug
RenalCommon (1% to 10%): Increased creatinine kinase
Postmarketing reports: Hematuria
RespiratoryCommon (1% to 10%): Rhinitis, sinusitis, dyspnea, sinus congestion, nasal congestion
Rare (less than 0.1%): Epistaxis
Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.
Source: Drugs.com Vardenafil Hydrochloride (www.drugs.com/vardenafil.html).
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