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This is not a list of all drugs or health problems that interact with ursodiol.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take ursodiol with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
Use ursodiol as ordered by your doctor. Read all information given to you. Follow all instructions closely.
All products:
Tablets:
What do I do if I miss a dose?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
All products:
Tablets:
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Medical Disclaimer
Other brands: Actigall, Urso, Urso Forte
Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.
Source: Drugs.com Ursodiol (www.drugs.com/ursodiol.html).
Commonly reported side effects of ursodiol include: back pain. Other side effects include: arthralgia, alopecia, arthritis, and pharyngitis. See below for a comprehensive list of adverse effects.
Applies to ursodiol: oral capsule, oral tablet
Along with its needed effects, ursodiol may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking ursodiol:
More common
Less common
Incidence not known
Some side effects of ursodiol may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
Less common
Rare
Incidence not known
Applies to ursodiol: oral capsule, oral tablet
The most commonly reported side effects included abdominal pain, diarrhea, constipation, and headache.
Very common (10% or more): Abdominal pain (up to 43.2%), diarrhea (up to 27.1%), constipation (up to 26.4%), nausea (up to 17.4%), dyspepsia (up to 16.8%), vomiting (up to 13.7%)
Common (1% to 10%): Cholecystitis, flatulence, gastrointestinal disorder, pasty stools, peptic ulcer
Very rare (less than 0.01%): Calcification of gallstones, severe upper right abdominal pain
Frequency not reported: Esophagitis
Postmarketing reports: Abdominal discomfort
Calcification of gallstones may result in surgery, as bile acid therapy alone may not be able to dissolve the calcifications.
Severe upper right abdominal pain occurred in patients with primary biliary cirrhosis.
Very common (10% or more): Headache (up to 24.8%), dizziness (up to 16.5%)
Very common (10% or more): Upper respiratory tract infection (up to 15.5%), sinusitis (up to 11%)
Common (1% to 10%): Bronchitis, coughing, pharyngitis, rhinitis
Postmarketing reports: Cough, laryngeal edema
Very common (10% or more): Viral infection (up to 19.4%)
Common (1% to 10%): Influenza-like symptoms
Very common (10% or more): Back pain (up to 11.8%)
Common (1% to 10%): Arthralgia, arthritis, musculoskeletal pain, myalgia
Common (1% to 10%): Alopecia, skin rash/rash
Very rare (less than 0.01%): Urticaria
Frequency not reported: Increased pruritus/pruritus
Postmarketing reports: Facial edema
Common (1% to 10%): Leukopenia, thrombocytopenia
Common (1% to 10%): Dysmenorrhea, urinary tract infection
Common (1% to 10%): Fatigue
Frequency not reported: Asthenia, fever, other toxicity
Postmarketing reports: Malaise, pyrexia
Drug hypersensitivity reactions included angioedema, facial edema, laryngeal edema, and urticaria.
Common (1% to 10%): Allergy
Frequency not reported: Allergic reactions
Postmarketing reports: Angioedema, drug hypersensitivity
Common (1% to 10%): Insomnia
Frequency not reported: Sleep disturbance
Common (1% to 10%): Elevated blood glucose
Frequency not reported: Anorexia
Common (1% to 10%): Chest pain
Postmarketing reports: Peripheral edema
Common (1% to 10%): Elevated creatinine
Very rare (less than 0.01%): Decompensation of hepatic cirrhosis
Frequency not reported: Increased cholestasis
Postmarketing reports: Aggravation of pre-existing jaundice/jaundice, ALT increased, AST increased, blood alkaline phosphatase increased, blood bilirubin increased, GGT increased, hepatic enzyme increased, liver function tests abnormal, transaminases increased
Decompensation of hepatic cirrhosis occurred in patients with advanced stages of primary biliary cirrhosis. The condition partially regressed after treatment was discontinued.
Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.
Source: Drugs.com Ursodiol (www.drugs.com/ursodiol.html).
July 13, 2020
July 13, 2020
July 13, 2020
July 13, 2020
July 13, 2020
June 26, 2020
