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Unisom sleepmelts

Generic Name: Diphenhydramine (Sleep Aid) Orally Disintegrating Tablets (dye fen HYE dra meen)
Brand Name: Unisom SleepMelts
Easy-to-read patient leaflet for Unisom SleepMelts. Includes indications, proper use, special instructions, precautions, and possible side effects.
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Drug Information:
This is not a list of all drugs or health problems that interact with this medicine (Unisom SleepMelts). Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this medicine (Unisom SleepMelts) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor. Use this medicine (Unisom SleepMelts) as ordered by your doctor. Read all information given to you. Follow all instructions closely. Learn more

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Unisom sleepmelts Side Effects

Note: This document contains side effect information about diphenhydramine. Some of the dosage forms listed on this page may not apply to the brand name Unisom SleepMelts.

In Summary

More frequent side effects include: sedated state and thickening of bronchial secretions. See below for a comprehensive list of adverse effects.

For the Consumer

Applies to diphenhydramine: oral capsules and tablets, parenteral injection

Side effects include:

Sedation, sleepiness, dizziness, disturbed coordination, epigastric distress, thickening of bronchial secretions.

For Healthcare Professionals

Applies to diphenhydramine: compounding powder, injectable solution, oral capsule, oral disintegrating strip, oral liquid, oral tablet, oral tablet chewable, oral tablet disintegrating

General

The most commonly reported side effects included somnolence, dizziness, and incoordination.

Nervous system

Common (1% to 10%): Sedation/somnolence/sleepiness, drowsiness, unsteadiness, dizziness, headache, attention disturbance

Rare (0.01% to 0.1%): Extrapyramidal effects, tremor, convulsions

Frequency not reported: Paresthesia, dyskinesia/muscle dyskinesia, vertigo, neuritis, incoordination, psychomotor impairment, activation of epileptogenic foci

Drowsiness usually diminishes after a few days.

Gastrointestinal

Common (1% to 10%): Dry mouth

Frequency not reported: Gastrointestinal disturbance, nausea, vomiting, constipation, diarrhea, dyspepsia, epigastric distress

Other

Common (1% to 10%): Fatigue

Frequency not reported: Lassitude, tinnitus, acute labyrinthitis, asthenia, chills, impaired performance (including impaired driving, work, and/or information processing)

Psychiatric

Rare (0.01% to 0.1%): Confusion, depression, sleep disturbances

Frequency not reported: Paradoxical excitation/excitation, agitation, increased energy, restlessness, nervousness, euphoria, anxiety, hallucinations, insomnia, irritability

Cardiovascular

Rare (0.01% to 0.1%): Palpitations, hypotension, arrhythmia

Frequency not reported: Tachycardia, chest tightness, extrasystoles

Hematologic

Rare (0.01% to 0.1%): Blood disorders

Frequency not reported: Hemolytic anemia, thrombocytopenia, agranulocytosis

Hypersensitivity

Rare (0.01% to 0.1%): Hypersensitivity reactions

Frequency not reported: Angioedema, anaphylactic shock

Hepatic

Rare (0.01% to 0.1%): Liver dysfunction

Dermatologic

Frequency not reported: Rash, urticaria, skin rashes, erythema, photosensitivity, pruritus, drug rash, excessive perspiration

Respiratory

Frequency not reported: Dyspnea, thickening of bronchial secretions, throat tightening, wheezing, nasal stuffiness, dry nose or throat

Genitourinary

Frequency not reported: Urinary hesitancy/difficulty/retention, dysuria, early menses

Ocular

Frequency not reported: Blurred vision, dry eyes, diplopia

Metabolic

Frequency not reported: Increased appetite, anorexia

Musculoskeletal

Frequency not reported: Muscle twitching/weakness

Editorial References and Review

Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.

Source: Drugs.com Unisom Sleepmelts (www.drugs.com/cdi/unisom-sleepmelts.html).

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