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Ultane

Generic Name: Sevoflurane (see-voe-FLOO-rane)
Brand Names: Ultane
Ultane (sevoflurane) is an anesthetic. It works by depressing activity in the central nervous system, which causes loss of consciousness. Includes Ultane side effects, interactions and indications.
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Drug Information:
Causing general anesthesia (loss of consciousness) before and during surgery. Ultane is an anesthetic. It works by depressing activity in the central nervous system, which causes loss of consciousness. Contact your doctor or health care prOvider right away if any of these apply to you. Some medical conditions may interact with Ultane . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you: Some MEDICINES MAY INTERACT with Ultane . Tell your health care prOvider if you are taking any other medicines, especially any of the following: Learn more

Ultane Side Effects

Ultane Side Effects

Note: This document contains side effect information about sevoflurane. Some of the dosage forms listed on this page may not apply to the brand name Ultane.

In Summary

More frequent side effects include: tachycardia. See below for a comprehensive list of adverse effects.

For the Consumer

Applies to sevoflurane: inhalation liquid

Along with its needed effects, sevoflurane (the active ingredient contained in Ultane) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. While you are receiving and recovering from an inhalation anesthetic like sevoflurane, your health care professional will closely follow its effects. However, some effects may not be noticed until later.

Some side effects of sevoflurane may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Cough
  • dizziness
  • drowsiness
  • increased amount of saliva
  • nausea
  • shivering
  • vomiting

Less common

  • Headache

For Healthcare Professionals

Applies to sevoflurane: inhalation liquid

General

The most common adverse events were nausea, vomiting, hypotension, agitation, and cough.

Gastrointestinal

Very common (10% or more): Nausea (25%), vomiting (18%)

Common (1% to 10%): Increased salivation

Uncommon (0.1% to 1%): Dry mouth

Cardiovascular

Very common (10% or more): Hypotension (11%), bradycardia

Common (1% to 10%): Tachycardia, hypertension

Uncommon (0.1% to 1%): Arrhythmia, ventricular extrasystoles, supraventricular extrasystoles, complete AV block, bigeminy, inverted T wave, atrial fibrillation, atrial arrhythmia, second degree AV block, S-T depressed, extrasystoles

Frequency not reported: QT prolongation, torsade de pointes

Postmarketing reports: Cardiac arrest

Respiratory

Very common (10% or more): Cough increased (11%),

Common (1% to 10%): Laryngospasm, airway obstruction, breath holding, apnea, respiratory disorder

Uncommon (0.1% to 1%): Sputum increased, hypoxia, wheezing, bronchospasm, hyperventilation, pharyngitis, hiccup, hypoventilation, dyspnea, stridor, hypoxia, asthma

Postmarketing reports: Pulmonary edema

Psychiatric

Very common (10% or more): Agitation (up to 15%)

Uncommon (0.1% to 1%): Crying, nervousness, confusion, insomnia, confusional state

Nervous system

Common (1% to 10%): Somnolence, dizziness, movement

Uncommon (0.1% to 1%): Syncope, hypertonia, taste perversion

Postmarketing reports: Seizures, dystonia

Other

Common (1% to 10%): Shivering, fever, hypothermia, headache, blood fluoride increased

Uncommon (0.1% to 1%): Asthenia, pain, fluorosis,

Rare (less than 0.1%): Malignant hyperthermia

Hematologic

Common (1% to 10%): White blood cell count abnormal

Uncommon (0.1% to 1%): Hemorrhage, leukocytosis, thrombocytopenia, leukopenia

Postmarketing reports: Transient elevations in white blood cell count

Hepatic

Common (1% to 10%): Liver function test abnormal

Uncommon (0.1% to 1%): Increases in AST, increases in ALT, bilirubinemia

Postmarketing reports: Hepatic dysfunction, hepatitis, jaundice, hepatic necrosis, hepatic failure, transient elevations in liver function tests

Metabolic

Common (1% to 10%): Blood glucose abnormal

Uncommon (0.1% to 1%): Increases in LDH, increases in alkaline phosphatase, hypophosphatemia, acidosis, hyperglycemia

Postmarketing reports: Transient elevations in glucose

Renal

Uncommon (0.1% to 1%): Increases in BUN, increases in creatinine, glycosuria, albuminuria,

Frequency not reported: Mild impairment of renal concentrating ability

Postmarketing reports: Acute renal failure

Ocular

Uncommon (0.1% to 1%): Amblyopia, conjunctivitis

Genitourinary

Uncommon (0.1% to 1%): Urination impaired, urine abnormality, urinary retention, oliguria

Dermatologic

Uncommon (0.1% to 1%): Pruritus, rash

Hypersensitivity

Postmarketing reports: Allergic reactions, urticaria, bronchospasm, anaphylactic or anaphylactoid reaction, hypersensitivity (including contact dermatitis, rash, dyspnea, wheezing, chest discomfort, swelling face, or anaphylactic reaction)

Musculoskeletal

Postmarketing reports: Muscle twitching

Editorial References and Review

Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.

Source: Drugs.com Ultane (www.drugs.com/ultane.html).