Loading

Please wait...

Trulance

Generic Name: plecanatide (ple KAN a tide)
Brand Names: Trulance
Trulance (plecanatide) is used to treat chronic idiopathic constipation (CIC) and irritable bowel syndrome with constipation (IBS-C). Includes Trulance side effects, interactions and indications.
  • Prescription Settings
  • X
  • Local Pharmacy Pickup available at . Pick up your medication at any of our participating pharmacies.
  • Mail Order Home Delivery available at , the easiest way to receive your medications.
  • Learn more

Trulance Coupons & Prices

Set your location
for drug prices near you

Enter your zip code

Please wait while the prices are loaded...
Click here to try again.

Don’t see your pharmacy listed? Most pharmacies accept our discounts, so have your pharmacist enter this coupon to see if you will save money:

Drug Information:
Trulance (plecanatide) is used to treat chronic idiopathic constipation or irritable bowel syndrome with constipation. Trulance works by activating certain substances within your intestines that help increase fluid secretion and muscle movement. Trulance also causes changes in the consistency of your stools. You should not use Trulance if you are allergic to plecanatide, or if you have a blockage in your intestines. Adults who cannot swallow Trulance tablets whole may crush the tablet and mix with applesauce or dissolve the tablet in water before swallowing. Trulance tablets may also be taken with water by adults through a nasogastric or gastric feeding tube. Learn more

Pickup / Home Delivery

USARx offers multiple ways to purchase this medication. Choose the Best option for you!

  • Guaranteed Price
    Local Pharmacy Pickup

    Pay this amount and pick up your prescription at ANY Retail pharmacy of your choice! Walgreens, CVS, Walmart, etc.

  • 30-day supply
    90-day supply
    Mail Order Home Delivery

    The easiest way to receive your medications.

Trulance Side Effects

Note: This document contains side effect information about plecanatide. Some of the dosage forms listed on this page may not apply to the brand name Trulance.

In Summary

More frequent side effects include: diarrhea. See below for a comprehensive list of adverse effects.

For the Consumer

Applies to plecanatide: oral tablet

Warning

Oral route (Tablet)

Plecanatide is contraindicated in patients less than 6 years of age; in nonclinical studies in young juvenile mice administration of a single oral dose of plecanatide caused deaths due to dehydration. Avoid use of plecanatide in patients 6 years to less than 18 years of age. The safety and effectiveness of plecanatide have not been established in patients less than 18 years of age.

Along with its needed effects, plecanatide (the active ingredient contained in Trulance) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking plecanatide:

Less common

  • Severe diarrhea

Some side effects of plecanatide may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

  • Bladder pain
  • bloody or cloudy urine
  • body aches or pain
  • chills
  • cough
  • difficult, burning, or painful urination
  • difficulty with breathing
  • dizziness
  • ear congestion
  • excess air or gas in the stomach or bowels
  • fever
  • full or bloated feeling
  • headache
  • loss of voice
  • lower back or side pain
  • muscle aches
  • nasal congestion
  • nausea
  • pain or tenderness around the eyes and cheekbones
  • passing gas
  • pressure in the stomach
  • sneezing
  • sore throat
  • stuffy or runny nose
  • swelling of the abdominal or stomach area
  • tightness of the chest
  • unusual tiredness or weakness

For Healthcare Professionals

Applies to plecanatide: oral tablet

Gastrointestinal

Common (1% to 10%): Diarrhea

Frequency not reported: Abdominal distention, flatulence, abdominal tenderness

Hepatic

In clinical trials, there were 2 patients with ALT greater than 5 to 15 times the upper limit of normal (ULN) and 3 patients with AST greater than 5 x ULN.

Frequency not reported: Increased liver biochemical tests

Respiratory

Frequency not reported: Sinusitis, upper respiratory tract infection

Editorial References and Review

Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.

Source: Drugs.com Trulance (www.drugs.com/trulance.html).