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Note: This document contains side effect information about fluocinolone / hydroquinone / tretinoin topical. Some of the dosage forms listed on this page may not apply to the brand name Tri-Luma.
In SummaryCommon side effects of Tri-Luma include: burning sensation, desquamation, pruritus, erythema of skin, and xeroderma. See below for a comprehensive list of adverse effects.
For the ConsumerApplies to fluocinolone/hydroquinone/tretinoin topical: topical application cream
Along with its needed effects, fluocinolone/hydroquinone/tretinoin topical may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking fluocinolone/hydroquinone/tretinoin topical:
More common
Less common
Incidence not known
Some side effects of fluocinolone / hydroquinone / tretinoin topical may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Less common
For Healthcare Professionals
Applies to fluocinolone / hydroquinone / tretinoin topical: topical cream
GeneralThe most commonly reported side effects included erythema, desquamation, burning, and dryness.
DermatologicVery common (10% or more): Erythema (up to 41%), desquamation (up to 38%), dryness (up to 14%), pruritus (up to 11%)
Common (1% to 10%): Acne, telangiectasia, rosacea, papules, acne-like rash, rash, vesicles, pigmentary changes
Postmarketing reports: Itching, folliculitis, acneiform eruptions, hypopigmentation, perioral dermatitis, secondary infection, skin atrophy, striae, miliaria, allergic contact dermatitis
Nervous systemVery common (10% or more): Burning (18%)
Common (1% to 10%): Paresthesia
LocalCommon (1% to 10%): Irritation
GastrointestinalCommon (1% to 10%): Dry mouth
Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/3/2022.
Source: Drugs.com Tri-luma (www.drugs.com/mtm/tri-luma.html).
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