Please wait...

Quick Stats

Offers Claimed:


Downloaded Today:


Trazodone hcl Prescription
view details
Generic Name: trazodone (TRAZ oh done)
Brand Names: Desyrel, Desyrel Dividose, Oleptro
Trazodone is a tetracyclic antidepressant used to treat depression and anxiety disorders. Includes trazodone side effects, interactions and indications.
Generic Name: trazodone (TRAZ oh done)
Brand Names: Desyrel, Desyrel Dividose, Oleptro
Trazodone is a tetracyclic antidepressant used to treat depression and anxiety disorders. Includes trazodone side effects, interactions and indications.
  • Select Your Prescription Settings
  • X
1 tablets of Trazodone Hcl 40 mg
  • Select Your Prescription Settings
  • X

Quick Stats

Offers Claimed: 178

Downloaded Today: 9

Set your location
for drug prices near you

Trazodone Hcl Coupons & Prices

Set your location
for drug prices near you

Enter your ZIP Code

Marketplace Offer

No insurance needed
Prescribed during Sesame visit
Fast & free delivery
Please wait while the prices are loaded...
Click here to try again.

Don’t see your pharmacy listed? Most pharmacies accept our discounts, so have your pharmacist enter this coupon to see if you will save money:

Trazodone Hcl Drug Information:

Trazodone is an antidepressant that belongs to a group of drugs called selective serotonin reuptake inhibitors (SSRIs). It affects chemicals in the brain that may be unbalanced in people with depression. Trazodone is used to treat major depressive disorder. It may help to improve your mood, appetite, and energy level as well as decrease anxiety and insomnia related to depression. Trazodone works by helping to restore the balance of a certain natural chemical (serotonin) in the brain. You should not use trazodone if you are allergic to it, or if you are being treated with Methylene Blue injection. Learn more

Trazodone hcl Medicare Coverage

Trazodone hcl Medicare Overview

Does Medicare cover Trazodone hcl?


100% of Medicare Part D and Medicare Advantage plans cover this drug.
How much is my Trazodone hcl co-pay with Medicare?

It depends. Which coverage stage are you in? Click on a tab below…


$95 – $296

In the Deductible co-pay stage, you are responsible for the full cost of your prescriptions. Your Medicare deductible cannot exceed $360 in 2016.

Ways to Save on Trazodone hcl

Here are some ways that may lower the cost of your trazodone hcl prescription.

  • Instead of Medicare, Use a USA Rx Coupon

    If your Medicare co-pay is higher, you can save money by using a USARx coupon instead.

Trazodone Hcl Side Effects

In Summary

Commonly reported side effects of trazodone include: blurred vision, dizziness, drowsiness, headache, nausea, vomiting, and xerostomia. Other side effects include: syncope, edema, ataxia, confusion, diarrhea, hypotension, insomnia, sedated state, and tachycardia. See below for a comprehensive list of adverse effects.

For the Consumer

Applies to trazodone: oral tablet


Oral route (Tablet, Extended Release; Tablet)

Antidepressants increased the risk compared to placebo of suicidal thinking and behavior in children, adolescents, and young adults with major depressive disorder (MDD) and other psychiatric disorders in short-term studies. Short-term studies did not show an increase in the risk of suicidality with antidepressants compared with placebo in adults beyond age 24, and there was a reduction in risk with antidepressants compared with placebo in adults aged 65 or older. The use of trazodone hydrochloride or any other antidepressant in a child, adolescent, or young adult must balance this risk with the clinical need. Closely monitor patients of all ages for clinical worsening, suicidality, or unusual changes in behavior. Families and caregivers should be advised of the need for close observation and communication with the prescriber. Not approved for pediatric use.

Along with its needed effects, trazodone may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking trazodone:

More common

  • Blurred vision
  • confusion
  • dizziness
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • lightheadedness
  • sweating
  • unusual tiredness or weakness

Less common

  • Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  • confusion about identity, place, and time
  • decreased concentration
  • fainting
  • general feeling of discomfort or illness
  • headache
  • lack of coordination
  • muscle tremors
  • nervousness
  • pounding in the ears
  • shortness of breath
  • slow or fast heartbeat
  • swelling


  • Skin rash
  • unusual excitement

Some side effects of trazodone may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Dry mouth (usually mild)
  • muscle or bone pain
  • trouble sleeping
  • trouble with remembering
  • unpleasant taste

Less common

  • Constipation
  • continuing ringing or buzzing or other unexplained noise in the ears
  • diarrhea
  • hearing loss
  • muscle aches or pains
  • weight loss

For Healthcare Professionals

Applies to trazodone: compounding powder, oral tablet, oral tablet extended release


The most commonly reported side effects included drowsiness, dry mouth, dizziness, and lightheadedness.

Nervous system

Very common (10% or more): Drowsiness (up to 41%), dizziness (up to 28%), lightheadedness (up to 28%), headache (up to 20%)

Common (1% to 10%): Decreased concentration, head full-heavy, incoordination, syncope, tremor

Frequency not reported: Akathisia, altered taste, convulsion, decreased alertness, dystonia, expressive aphasia, impaired memory, impaired speech, memory disturbance, motor impairment, neuroleptic malignant syndrome, numbness, paresthesia, serotonin syndrome, vertigo

Postmarketing reports: Aphasia, ataxia, cerebrovascular accident, extrapyramidal symptoms, grand mal seizures, stupor, tardive dyskinesia

Drowsiness has occurred during the first few days of treatment, and usually disappeared with continue administration.


Very common (10% or more): Dry mouth (up to 34%), nausea (up to 13%), vomiting (up to 13%)

Common (1% to 10%): Abdominal disorder, constipation, diarrhea, gastric disorder

Frequency not reported: Dyspepsia, flatulence, gastroenteritis, hypersalivation, increased salivation, paralytic ileus, stomach pain

Postmarketing reports: Increased amylase


Very common (10% or more): Hypertension (up to 20%)

Common (1% to 10%): Edema, hypotension

Frequency not reported: Bradycardia, cardiac arrhythmias, chest pain, ECG abnormalities, increased risk of bleeding, orthostatic hypotension, palpitations, premature ventricular beats, QT prolongation, sinus bradycardia, tachycardia, Torsade de pointes, ventricular couplets, ventricular tachycardia

Postmarketing reports: Atrial fibrillation, cardiac arrest, cardiospasm, conduction block, congestive heart failure, myocardial infarction, vasodilation, ventricular ectopic activity

QT prolongation, Torsade de pointes, and ventricular tachycardia have been reported in patients with doses up to 100 mg/day.


Very common (10% or more): Blurred vision (up to 15%)

Common (1% to 10%): Itching eyes, red eyes, tired eyes

Frequency not reported: Angle-closure glaucoma, myoclonus

Postmarketing reports: Diplopia


Very common (10% or more): Nervousness (up to 15%)

Common (1% to 10%): Confusion

Frequency not reported: Activation of mania/hypomania, aggressive reaction, agitation (sometimes exacerbating to delirium), anxiety, cognitive impairment, confusional state, delusions, discontinuation syndrome, hallucinations, hypomania, increased libido, insomnia, libido decreased, mania, nightmares, restlessness, suicidal behavior, suicidal ideation, suicidal thoughts, withdrawal syndrome

Postmarketing reports: Abnormal dreams, paranoid reaction, psychoses


Very common (10% or more): Fatigue (up to 11%)

Common (1% to 10%): Aches, malaise, pain

Frequency not reported: Fever, weakness

Postmarketing reports: Chills, unexplained death


Common (1% to 10%): Weight gain, weight loss

Frequency not reported: Anorexia, hyponatremia, increased appetite


Common (1% to 10%): Nasal congestion, sinus congestion

Frequency not reported: Dyspnea, shortness of breath

Postmarketing reports: Apnea


Common (1% to 10%): Skin condition

Frequency not reported: Hyperhidrosis, pruritus, skin rash

Postmarketing reports: Alopecia, hirsutism, leuconychia, psoriasis, urticaria


Frequency not reported: Delayed urine flow, early menses, hematuria, impotence, increased urinary frequency, micturition disorders, missed periods, priapism, retrograde ejaculation

Postmarketing reports: Breast engorgement, breast enlargement, clitorism, lactation, urinary incontinence, urinary retention


Frequency not reported: Cholestasis intrahepatic, elevated liver enzymes, fulminant hepatitis, hepatic failure with potentially fatal outcome, hepatic function abnormalities, hepatitis, hepatocellular damage, jaundice, severe hepatic disorders

Postmarketing reports: Cholestasis, hyperbilirubinemia, liver enzyme alterations


Frequency not reported: Agranulocytosis, anemia, blood dyscrasias, eosinophilia, leukopenia, thrombocytopenia

Postmarketing reports: Hemolytic anemia, leukocytosis, methemoglobinemia


Frequency not reported: Arthralgia, back pain, limb pain, muscle twitches, myalgia


Frequency not reported: Allergic reactions


Frequency not reported: Influenza-like symptoms


Frequency not reported: Syndrome of inappropriate antidiuretic hormone (SIADH) secretion

Editorial References and Review

Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/3/2022.

Source: Drugs.com Trazodone Hcl (www.drugs.com/trazodone.html).