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Applies to tranexamic acid: oral tablet
Other dosage forms:
Along with its needed effects, tranexamic acid may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking tranexamic acid:
Incidence not known
Some side effects of tranexamic acid may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Incidence not known
Applies to tranexamic acid: compounding powder, intravenous solution, oral tablet
Gastrointestinal side effects have frequently included nausea, vomiting, and diarrhea. Abdominal pain has also been reported.
Nervous system side effects have included giddiness, dizziness, headache, tension headache, and migraine.
Hematologic side effects have included thromboembolic events (e.g., deep vein thrombosis, pulmonary embolism, cerebral thrombosis, acute renal cortical necrosis, and central retinal artery and vein obstruction) and anemia.
Hypersensitivity side effects have included allergic skin reactions, anaphylactic shock and anaphylactoid reactions.
A case of severe allergic reaction to tranexamic acid was reported involving a subject on her fourth cycle of treatment who experienced dyspnea, tightening of her throat, and facial flushing that required emergency medical treatment.
Ocular side effects have rarely included disturbances of color vision and retinal artery occlusion.
Musculoskeletal side effects have included back pain, musculoskeletal pain, muscle cramps and spasms, myalgia, and arthralgia including joint stiffness and swelling.
Respiratory side effects have included nasal and sinus symptoms including nasal, respiratory tract and sinus congestion, sinusitis, acute sinusitis, sinus headache, and allergic sinusitis and sinus pain.
Cardiovascular side effects have included hypotension when intravenous administration exceeded 1 mL per minute.
Genitourinary side effects have included ureteral obstruction due to clot formation in patients with upper urinary tract bleeding.