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More frequently reported side effects include: nausea, bitter taste, and metallic taste. See below for a comprehensive list of adverse effects.
Applies to tinidazole: oral tablet
Oral route (Tablet)
Carcinogenicity has been seen in mice and rats treated chronically with another agent in the nitroimidazole class (metronidazole). Although such data have not been reported for tinidazole, unnecessary use of tinidazole should be avoided.
Along with its needed effects, tinidazole may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking tinidazole:
Some side effects of tinidazole may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Applies to tinidazole: compounding powder, oral tablet
Reported side effects were typically mild, infrequent, and self-limiting. Gastrointestinal side effects were reported most often.
Common (1% to 10%): Nausea, dyspepsia/cramps/epigastric discomfort, vomiting, constipation, diarrhea, abdominal pain, flatulence
Rare (less than 0.1%): Furry tongue
Frequency not reported: Tongue discoloration, stomatitis, dryness of mouth, salivation, oral candidiasis, glossitis
Common (1% to 10%): Metallic/bitter taste, headache, dizziness, vertigo
Rare (less than 0.1%): Coma
Frequency not reported: Convulsions, peripheral neuropathy, ataxia, giddiness, drowsiness, burning sensation, paresthesia, hypoesthesia/numbness, sensory disturbances, dysgeusia
Common (1% to 10%): Weakness/fatigue/malaise
Frequency not reported: Flushing, fever/pyrexia, thirst, Candida overgrowth, fatigue, malaise
In a study involving 450 patients with fixed drug eruptions, 8 patients were found to have this oral drug as the probable causative agent. The fixed drug eruptions varied as to duration, shape and size, symptoms, number of lesions, and body site(s) affected. The study did not break these factors down for each individual causative agent.
Common (1% to 10%): Allergic dermatitis, pruritus
Frequency not reported: Urticaria, rash, sweating, angioedema, fixed drug eruption
Common (1% to 10%): Anorexia, decreased appetite
Common (1% to 10%): Urinary tract infection, dysuria/painful urination, urine abnormality, pelvic pain, vulvovaginal discomfort, vaginal odor, menorrhagia
Frequency not reported: Darkened urine/chromaturia, increased vaginal discharge, female genital pruritus, Candida vaginitis
Common (1% to 10%): Upper respiratory tract infection
Rare (less than 0.1%): Bronchospasm, dyspnea, pharyngitis
Rare (less than 0.1%): Confusion, depression
Frequency not reported: Insomnia
Rare (less than 0.1%): Reversible thrombocytopenia
Frequency not reported: Neutropenia, leukopenia, increased eosinophil count, decreased hemoglobin
Severe acute hypersensitivity reactions have been reported during initial or subsequent exposure to this drug.
Frequency not reported: Drug hypersensitivity
Postmarketing reports: Severe acute hypersensitivity reactions, hypersensitivity reactions (included urticaria, pruritus, rash, flushing, sweating, dryness of mouth, fever, burning sensation, thirst, salivation, angioedema, Stevens-Johnson syndrome, erythema multiforme)
Frequency not reported: Hepatic abnormalities (included raised transaminase level), increased AST, increased blood bilirubin
Frequency not reported: Increased blood urea
Frequency not reported: Palpitations
Frequency not reported: Arthralgias, myalgias, arthritis
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