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Temazepam

Temazepam Prescription
Generic Name: temazepam (te MAZ e pam)
Brand Names: Restoril
Temazepam is used to treat insomnia (trouble sleeping). Learn about side effects, interactions and indications.

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Temazepam Drug Information:

Temazepam is a benzodiazepine (ben-zoe-dye-AZE-eh-peen). Temazepam affects chemicals in the brain that may be unbalanced in people with sleep problems (insomnia). Temazepam is used to treat insomnia symptoms, such as trouble falling asleep or staying asleep. Do not use temazepam if you are pregnant. This medicine can cause birth defects or life-threatening withdrawal symptoms in a newborn. Temazepam may be habit-forming and should be used only by the person it was prescribed for. This medicine should never be shared with another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it.Misuse of habit-forming medicine can cause addiction, overdose, or death. Learn more

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Temazepam Side Effects

In Summary

More frequently reported side effects include: dizziness, insomnia, lethargy, and irritability. See below for a comprehensive list of adverse effects.

For the Consumer

Applies to temazepam: oral capsule

Warning

Oral route (Capsule)

Concomitant use of benzodiazepines and opioids may result in profound sedation, respiratory depression, coma, and death. Reserve concomitant prescribing for patients with inadequate alternative treatment options. Limit dosages and durations to the minimum required and follow patients for signs and symptoms of respiratory depression and sedation.

Along with its needed effects, temazepam may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking temazepam:

Less common

  • False or unusual sense of well-being
  • fear or nervousness
  • mood or mental changes

Rare

  • Difficult or labored breathing
  • fast, irregular, pounding, or racing heartbeat or pulse
  • large, hive-like swelling on face, eyelids, lips, tongue, throat, hands, legs, feet, sex organs
  • loss of appetite
  • loss of memory
  • nightmares
  • problems with memory
  • seeing, hearing, or feeling things that are not there
  • shakiness and unsteady walk
  • tightness in the chest
  • uncontrolled eye movements
  • unsteadiness, trembling, or other problems with muscle control or coordination
  • unusual excitement, nervousness, restlessness, or irritability
  • weight loss

Incidence not known

  • Muscle cramps
  • seizures
  • shakiness in the legs, arms, hands, or feet
  • stomach cramps
  • sweating
  • trembling or shaking of the hands or feet
  • vomiting

Get emergency help immediately if any of the following symptoms of overdose occur while taking temazepam:

Symptoms of overdose

  • Blurred vision
  • change in consciousness
  • confusion
  • decreased or absent reflexes
  • difficult or troubled breathing
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • irregular, fast, slow, or shallow breathing
  • loss of consciousness
  • pale or blue lips, fingernails, or skin
  • sleepiness or unusual drowsiness
  • unusual tiredness or weakness

Some side effects of temazepam may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

  • Diarrhea
  • dry mouth
  • feeling of constant movement of self or surroundings
  • headache
  • nausea
  • sensation of spinning
  • unusual dullness or feeling of sluggishness

Rare

  • Backache
  • burning eyes

For Healthcare Professionals

Applies to temazepam: oral capsule

General

The most commonly reported side effects included drowsiness, headache, and fatigue.

Nervous system

Lightheadedness, slurred speech, and unsteadiness usually occur at the start of treatment and disappear with repeated doses.

Common (1% to 10%): Dizziness, drowsiness, hangover, headache, lethargy, sedation, vertigo

Uncommon (0.1% to 1%): Ataxia, equilibrium loss, faintness, muzziness, sciatica, taste loss, tremor

Rare (0.01% to 0.1%): Dysarthria

Frequency not reported: Amnesia, anterograde amnesia, coma, convulsions, daytime drowsiness, epileptic seizures, extrapyramidal symptoms, extremity tingling, horizontal nystagmus, hypersensitivity to light/noise/physical contact, impaired concentration, lightheadedness, numbness, oversedation, perceptual disturbances, reduced alertness, seizures, slurred speech, unsteadiness

Psychiatric

Common (1% to 10%): Anxiety, confusion, depression, euphoria, nervousness, nightmares

Uncommon (0.1% to 1%): Decreased orgasm, disorientation, increased dreaming, irritability, libido changes, unmasking of depression, vivid dreams

Rare (0.01% to 0.1%): Restless sleep

Frequency not reported: Abuse, aggressiveness/aggression, agitation, broken sleep (with vivid dreams), confusional states, delusion, depersonalization, dependence, derealization, disinhibition, excitement, extreme anxiety, hallucinations, hostility, inappropriate behavior, insomnia, mood changes, numbed emotions, other adverse behavioral effects, overstimulation, physical dependence, psychological dependence, psychoses, psychotic manifestations, rage, rebound insomnia, restlessness, sexual arousal, sleep disturbance, stimulation, suicidal attempt, suicidal ideation, tension, withdrawal effects/symptoms

Dependence and numbed emotions usually occur at the start of treatment and disappear with repeated doses.

Gastrointestinal

Common (1% to 10%): Abdominal discomfort, diarrhea, dry mouth, nausea

Uncommon (0.1% to 1%): Gastrointestinal upset, vomiting

Rare (0.01% to 0.1%): Salivation changes

Frequency not reported: Abdominal cramps, constipation, gastrointestinal disturbances

Other

Common (1% to 10%): Fatigue, weakness

Uncommon (0.1% to 1%): Asthenia

Frequency not reported: Falls, hyperacusis, hypothermia, paradoxical reactions, rebound phenomenon, tinnitus

Ocular

Common (1% to 10%): Blurred vision

Uncommon (0.1% to 1%): Burning eyes

Rare (0.01% to 0.1%): Visual disturbances

Frequency not reported: Diplopia/double vision, photophobia

Double vision usually occurs at the start of treatment and disappears with repeated doses.

Dermatologic

Uncommon (0.1% to 1%): Allergic skin reactions, hyperhidrosis, macular rash, pruritus

Rare (0.01% to 0.1%): Skin reactions

Frequency not reported: Alopecia, sweating

Hematologic

Uncommon (0.1% to 1%): Increased neutrophils, leukocytosis

Rare (0.01% to 0.1%): Blood disorders, blood dyscrasias

Frequency not reported: Agranulocytosis, pancytopenia, thrombocytopenia

Hepatic

Uncommon (0.1% to 1%): Increased AST, increased bilirubin

Rare (0.01% to 0.1%): Abnormal liver function, jaundice

Frequency not reported: Increased liver enzymes

Genitourinary

Uncommon (0.1% to 1%): Impotence, proteinuria

Rare (0.01% to 0.1%): Incontinence, urinary retention

Cardiovascular

Uncommon (0.1% to 1%): Palpitations, tachycardia

Rare (0.01% to 0.1%): Hypotension

Frequency not reported: Lowering in blood pressure, mild systolic hypertension, orthostatic hypotension

Musculoskeletal

Uncommon (0.1% to 1%): Backache, leg cramps

Rare (0.01% to 0.1%): Impaired muscular function

Frequency not reported: Muscle pain, muscle weakness

Muscle weakness usually occurs at the start of treatment and disappears with repeated doses.

Respiratory

Respiratory depression usually occurs at the start of treatment and disappears with repeated doses.

Uncommon (0.1% to 1%): Breathlessness, dyspnea

Frequency not reported: Apnea, respiratory depression, worsening of obstructive pulmonary disease, worsening of sleep apnea

Metabolic

Uncommon (0.1% to 1%): Anorexia, increased serum alkaline phosphatase

Frequency not reported: Hyponatremia, loss of appetite

Renal

Uncommon (0.1% to 1%): Increased blood urea nitrogen

Hypersensitivity

Rare (0.01% to 0.1%): Fatal anaphylaxis

Frequency not reported: Hypersensitivity reactions, severe anaphylactic reaction, severe anaphylactoid reaction

Endocrine

Frequency not reported: Syndrome of inappropriate antidiuretic hormone secretion (SIADH)

Editorial References and Review

Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.

Source: Drugs.com Temazepam (www.drugs.com/temazepam.html).