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Syprine

Generic Name: trientine (TRYE en teen)
Brand Name: Syprine
Physician reviewed Syprine patient information - includes Syprine description, dosage and directions.
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Drug Information:
Syprine is a chelating (KEE-late-ing) agent. A chelating agent works by removing a heavy metal (such as lead, mercury, or copper) from the blood. Wilson's disease is a genetic metabolic defect that causes excess copper to build up in the body. Syprine is used to treat this inherited condition in people who cannot take Penicillamine. Syprine may also be used for purposes not listed in this medication guide. Follow all directions on your medicine label and package. Tell each of your healthcare prOviders about all your medical conditions, allergies, and all medicines you use. Learn more

Pickup / Home Delivery

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Syprine Side Effects

Note: This document contains side effect information about trientine. Some of the dosage forms listed on this page may not apply to the brand name Syprine.

For the Consumer

Applies to trientine: oral capsule

Along with its needed effects, trientine (the active ingredient contained in Syprine) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur while taking trientine:

More common

- Symptoms of anemia
  • Unusually pale skin
  • unusual tiredness

Rare

  • Fever
  • general feeling of discomfort, illness, or weakness
  • joint pain
  • skin rash, blisters, hives, or itching
  • swollen glands

Note: Signs of anemia are more likely to occur in children, menstruating women, and pregnant women, who usually need more iron than other patients. If these signs appear during trientine treatment, your doctor will need to do some tests.

For Healthcare Professionals

Applies to trientine: oral capsule

Nervous system

Frequency not reported: Myasthenia gravis

Gastrointestinal

Frequency not reported: Nausea, duodenitis, severe colitis, heartburn, epigastric pain and tenderness, acute gastritis, aphthoid ulcers, abdominal pain, melena

Hematologic

Very rare (less than 0.01%): Anemia, hypochromic microcytic anemia

Musculoskeletal

Frequency not reported: Systemic lupus erythematosus, dystonia, muscular spasm, cramps, muscle pain, rhabdomyolysis

Metabolic

Frequency not reported: Iron deficiency, anorexia

Dermatologic

Frequency not reported: Skin rash, thickening/fissuring/flaking of the skin

Other

Frequency not reported: Malaise, weakness

Editorial References and Review

Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.

Source: Drugs.com Syprine (www.drugs.com/mtm/syprine.html).