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Generic Name: calcipotriene topical (cal sih poh TRY een)
Brand Names: Calcitrene, Dovonex, Sorilux
Sorilux (calcipotriene) is used to treat psoriasis that has scaly patches (plaque psoriasis). Includes Sorilux side effects, interactions and indications.
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Drug Information:
Sorilux Foam contains calcipotriene, a man-made form of Vitamin D. It is involved in the growth and development of skin cells. Sorilux Foam is used to treat plaque psoriasis (psoriasis with scaly patches). Sorilux may also be used for purposes not listed in this medication guide. You should not use Sorilux if you are allergic to calcipotriene, or if you have high levels of Calcium in your blood (hypercalcemia). Before using Sorilux, tell your doctor if you are receiving photoTherapy (light treatments) for your psoriasis. Learn more

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Sorilux Side Effects

Note: This document contains side effect information about calcipotriene topical. Some of the dosage forms listed on this page may not apply to the brand name Sorilux.

For the Consumer

Applies to calcipotriene topical: topical cream, topical foam, topical ointment, topical solution

Along with its needed effects, calcipotriene topical (the active ingredient contained in Sorilux) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking calcipotriene topical:

More common

  • Skin redness, swelling, or itching
  • skin rash
  • worsening of psoriasis

Some side effects of calcipotriene topical may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Burning, dryness, irritation, peeling, or redness of the skin

Less common

  • Pain at the application site

Less common or rare

  • Darker color in the treated areas of the skin
  • pus in the hair follicles

For Healthcare Professionals

Applies to calcipotriene topical: topical cream, topical foam, topical ointment, topical solution


The most commonly reported side effects were burning, stinging, tingling, and skin irritation.


Very rare (less than 0.01%): Allergic reactions (including angioedema)


Very common (10% or more): Transient burning (about 23%), stinging (about 23%), tingling (about 23%), skin irritation (up to 15%), rash (11%)

Common (1% to 10%): Pruritus, dermatitis, contact dermatitis (including facial and perioral), dry skin, irritation, worsening of psoriasis, erythema, peeling

Uncommon (0.1% to 1%): Skin atrophy, hyperpigmentation, folliculitis, eczema

Frequency not reported: Transient changes in skin pigmentation, transient photosensitivity, urticaria, angioedema, skin exfoliation


Uncommon (0.1% to 1%): Hypercalcemia

Rare (less than 0.1%): Transient increases in serum calcium

Very rare (less than 0.01%): Hypercalcemia, hypercalciuria (especially if the total recommended dose is exceeded)


Very common (10% or more): Lesional/perilesional irritation (up to 39%), face and/or scalp irritation (up to 25%)


Frequency not reported: Periorbital or face edema

Editorial References and Review

Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.

Source: Drugs.com Sorilux (www.drugs.com/sorilux.html).