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Soolantra (ivermectin) is used to treat rosacea. Includes Soolantra side effects, interactions and indications.
Soolantra (ivermectin) is used to treat rosacea. Includes Soolantra side effects, interactions and indications.
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1 tablets of Soolantra 40 mg
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Soolantra Drug Information:

The U.S. Food and Drug Administration (FDA) approved Soolantra (Ivermectin) Cream, 1% for the once-daily topical treatment of inflammatory lesions, or bumps and pimples, of rosacea. Recent studies have suggested that generally harmless microscopic Demodex mites may be a cause of rosacea. Soolantra has both anti-inflammatory and antiparasitic activity. Soolantra is used to treat rosacea. It is a macrocyclic lactone. Exactly how it works to treat rosacea is unknown. Contact your doctor or health care prOvider right away if any of these apply to you. Learn more

Soolantra Side Effects

Note: This document contains side effect information about ivermectin topical. Some of the dosage forms listed on this page may not apply to the brand name Soolantra.

For the Consumer

Applies to ivermectin topical: topical application cream, topical application lotion

Along with its needed effects, ivermectin topical (the active ingredient contained in Soolantra) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Some side effects of ivermectin topical may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:


  • Burning, itching, redness, or stinging of the skin
  • burning, dry, or itching eyes
  • dandruff
  • discharge or excessive tearing
  • dry skin
  • redness, pain, or swelling of the eye, eyelid, or inner lining of the eyelid

For Healthcare Professionals

Applies to ivermectin topical: topical cream, topical lotion


The most frequently reported side effects included skin burning sensation, skin irritation, pruritus, and dry skin, occurring in 1% or less of patients.


Common (1% to 10%): Burning sensation

Uncommon (0.1% to 1%): Skin irritation, pruritus, dry skin

Frequency not reported: Erythema, contact dermatitis, dandruff


Common (1% to 10%): Muscle strain, back pain

Nervous system

Common (1% to 10%): Headache


Common (1% to 10%): Nasopharyngitis, upper respiratory tract infection, sinusitis


Common (1% to 10%): Seasonal allergy


Frequency not reported: Conjunctivitis, ocular hyperemia, eye irritation


Common (1% to 10%): Urinary tract infection

Editorial References and Review

Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/3/2022.

Source: Drugs.com Soolantra (www.drugs.com/soolantra.html).