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Solifenacin Succinate

Solifenacin succinate Prescription
Generic Name: solifenacin (sol ee FEN a sin)
Brand Name: VESIcare
Physician reviewed solifenacin patient information - includes solifenacin description, dosage and directions.

Average Savings for solifenacin succinate (generic): 68.14%
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Solifenacin Succinate Drug Information:

Solifenacin is used to treat symptoms of overactive bladder, such as frequent or urgent urination, and incontinence (urine leakage). Solifenacin may also be used for purposes not listed in this medication guide. You should not use solifenacin if you have untreated or uncontrolled narrow-angle glaucoma, a blockage in your digestive tract (stomach or intestines), or if you are unable to urinate. You should not use solifenacin if you are allergic to it, or if you have: untreated or uncontrolled narrow-angle glaucoma; Learn more

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Solifenacin Succinate Side Effects

In Summary

Commonly reported side effects of solifenacin include: constipation and xerostomia. Other side effects include: urinary tract infection and blurred vision. See below for a comprehensive list of adverse effects.

For the Consumer

Applies to solifenacin: oral tablet

Side effects requiring immediate medical attention

Along with its needed effects, solifenacin may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking solifenacin:

Less common

  • Bladder pain
  • bloody or cloudy urine
  • chills
  • decrease in the frequency of urination
  • decrease in urine volume
  • difficult, burning, or painful urination
  • difficulty in passing urine (dribbling)
  • fever
  • frequent urge to urinate
  • painful urination
  • swelling of the lower legs
  • unusual tiredness or weakness

Incidence not known

  • Bloating or swelling of the face, arms, hands, lower legs, or feet
  • chest pain or discomfort
  • fainting
  • irregular heartbeat recurrent
  • irregular or slow heart rate
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • rapid weight gain
  • shortness of breath
  • tingling of the hands or feet
  • unusual weight gain or loss
Side effects not requiring immediate medical attention

Some side effects of solifenacin may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

  • Acid or sour stomach
  • belching
  • body aches or pain
  • congestion
  • cough
  • diarrhea
  • discouragement
  • feeling sad or empty
  • general feeling of discomfort or illness
  • headache
  • heartburn
  • hoarseness
  • indigestion
  • irritability
  • joint pain
  • lack of appetite
  • loss of interest or pleasure
  • lower back or side pain
  • muscle aches and pains
  • nervousness
  • pounding in the ears
  • runny nose
  • shivering
  • slow or fast heartbeat
  • sore throat
  • stomach discomfort, upset, or pain
  • sweating
  • tender, swollen glands in the neck
  • tiredness
  • trouble concentrating
  • trouble with sleeping
  • trouble with swallowing
  • upper abdominal or stomach pain
  • voice changes

Incidence not known

  • Hives or welts
  • itching
  • redness of the skin
  • skin rash

For Healthcare Professionals

Applies to solifenacin: oral tablet

Gastrointestinal

Very common (10% or more): Dry mouth (up to 28%), constipation (up to 13%)

Common (1% to 10%): Nausea, dyspepsia, upper abdominal pain, vomiting

Uncommon (0.1% to 1%): Gastroesophageal reflux disease, dry throat, flatulence, throat irritation, eructation, thirst

Rare (less than 0.1%): Colonic obstruction, fecal impaction

Postmarketing reports: Ileus

Respiratory

Common (1% to 10%): Pharyngitis, cough, sinusitis, bronchitis

Uncommon (0.1% to 1%): Nasal dryness

Postmarketing reports: Dysphonia

Psychiatric

Common (1% to 10%): Depression

Postmarketing reports: Confusion, hallucinations, delirium, somnolence

Ocular

Common (1% to 10%): Blurred vision, dry eyes

Very rare (less than 0.01%): Glaucoma

Genitourinary

Common (1% to 10%): Urinary tract infection, urinary retention

Uncommon (0.1% to 1%): Cystitis, suprapubic pain, bladder pain, micturition urgency

Cardiovascular

Common (1% to 10%): Lower limb edema, hypertension

Uncommon (0.1% to 1%): Syncope, chest tightness, hot flushes

Postmarketing reports: Peripheral edema, QT prolongation, Torsade de Pointes, atrial fibrillation, tachycardia, palpitations, atrial fibrillation

Dermatologic

Uncommon (0.1% to 1%): Dry skin

Rare (0.01% to 0.1%): Pruritus, rash

Very rare (less than 0.01%): Erythema multiforme, urticaria, angioedema, exfoliative dermatitis

Immunologic

Common (1% to 10%): Influenza

Metabolic

Very rare (less than 0.01%): Decreased appetite, hyperkalemia

Hypersensitivity

Very rare (less than 0.01%): Hypersensitivity reactions (including angioedema with airway obstruction, rash, pruritus, urticaria, and anaphylactic reaction)

Other

Common (1% to 10%): Fatigue

Renal

Very rare (less than 0.01%): Renal impairment

Hepatic

Postmarketing reports: Abnormal liver function tests, AST (aspartate aminotransferase), ALT (alanine aminotransferase), GGT (gamma-glutamyl transferase)

Musculoskeletal

Common (1% to 10%): Arthralgia, back pain

Uncommon (0.1% to 1%): Neck pain

Postmarketing reports: Muscular weakness

Nervous system

Common (1% to 10%): Dizziness, insomnia

Uncommon (0.1% to 1%): Dysgeusia

Rare (0.01% to 0.1%): Headache

Postmarketing reports: Headache, tremors

Editorial References and Review

Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.

Source: Drugs.com Solifenacin Succinate (www.drugs.com/mtm/solifenacin.html).