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Skelaxin

Generic Name: metaxalone (me TAX a lone)
Brand Names: Skelaxin
Skelaxin (metaxalone) is used to treat skeletal muscle conditions such as pain or injury. Includes Skelaxin side effects, interactions and indications.
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Drug Information:
Skelaxin (Metaxalone) is a muscle relaxant. It works by blocking nerve impulses (or pain sensations) in the brain. Skelaxin is used together with rest and physical Therapy to treat skeletal muscle conditions such as pain or injury. Skelaxin may also be used for purposes not listed in this medication guide. You should not use Skelaxin if you have anemia (low red blood cells), or severe kidney or liver disease. You may need a dose adjustment or special tests to safely take Skelaxin. Skelaxin can cause side effects that may impair your thinking or Reactions. Be careful if you drive or do anything that requires you to be awake and alert. Avoid drinking Alcohol. It can increase some of the side effects of Metaxalone. Learn more

Skelaxin Side Effects

Skelaxin Side Effects

Note: This document contains side effect information about metaxalone. Some of the dosage forms listed on this page may not apply to the brand name Skelaxin.

For the Consumer

Applies to metaxalone: oral tablet

Along with its needed effects, metaxalone (the active ingredient contained in Skelaxin) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking metaxalone:

Incidence not known

  • Agitation
  • back, leg, or stomach pains
  • black, tarry stools
  • bleeding gums
  • chest pain
  • chills
  • clay-colored stools
  • confusion
  • cough
  • dark urine
  • diarrhea
  • difficulty in breathing or swallowing
  • dizziness
  • fast heartbeat
  • fever
  • general body swelling
  • headache
  • hives, itching, skin rash
  • loss of appetite
  • nausea
  • nosebleed
  • painful or difficult urination
  • pale skin
  • poor coordination
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • redness of the skin
  • restlessness
  • sore throat
  • sores, ulcers, or white spots on the lips or in the mouth
  • stomach pain
  • sweating
  • swelling of the face, throat, or tongue
  • swollen glands
  • talking or acting with excitement you cannot control
  • tightness in the chest
  • trembling or shaking
  • twitching
  • unpleasant breath odor
  • unusual bleeding or bruising
  • unusual tiredness or weakness
  • vomiting
  • vomiting of blood
  • yellowing of the eyes or skin

Some side effects of metaxalone may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Drowsiness
  • irritability
  • stomach or bowel upset

For Healthcare Professionals

Applies to metaxalone: oral tablet

Gastrointestinal

Common (1% to 10%): Nausea, vomiting, gastrointestinal upset

Nervous system

Common (1% to 10%): Drowsiness, dizziness, headache

Hematologic

Frequency not reported: Leukopenia, hemolytic anemia

Hypersensitivity

Rare (less than 0.1%): Anaphylactoid reaction, hypersensitivity reaction, rash (with or without pruritus)

Hepatic

Frequency not reported: Jaundice

Other

Frequency not reported: False-positive Benedict's tests (due to an unknown reducing substance)

A glucose-specific test may be used to differentiate findings.

Psychiatric

Common (1% to 10%): Nervousness, irritability

Editorial References and Review

Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.

Source: Drugs.com Skelaxin (www.drugs.com/skelaxin.html).