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Shingrix is a vaccine used for the prevention of herpes zoster. Herpes zoster is caused by the same virus (varicella) that causes chickenpox in children. When this virus becomes active again, it can cause herpes zoster, or shingles. Shingrix helps prevent shingles.
Shingrix works by exposing you to a small dose of inactive virus, which causes the body to develop immunity to the disease. This vaccine will not treat an active infection that has already developed in the body.
Shingrix is used to prevent herpes zoster virus (shingles) in people age 50 and older, including people who previously received a live zoster vaccine (Zostavax).
Shingrix will not treat chickenpox, shingles, or nerve pain caused by shingles (post-herpetic neuralgia).
You should not receive Shingrix if you have ever had a life-threatening allergic reaction to any vaccine containing zoster virus.
You should not receive the second shot if you had a life-threatening allergic reaction after the first shot.
To make sure this vaccine is safe for you, tell your doctor if you have ever had an allergic reaction to any vaccine.
You should not receive Shingrix if you have ever had a life-threatening allergic reaction to inactivated zoster virus vaccine.
Tell your doctor if you have ever had an allergic reaction to any vaccine.
It is not known whether zoster vaccine will harm an unborn baby. Tell your doctor if you are pregnant.
It may not be safe to breast-feed a baby shortly after you receive Shingrix. Ask your doctor about any risks.
Shingrix is given as an injection (shot) into a muscle. A healthcare provider will give you this injection.
Shingrix is usually given in a series of 2 shots. The second shot may be given any time within 2 to 6 months after the first shot.
You may receive Shingrix at the same time that you get a flu shot.
Read all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions.
Usual Adult Dose for Varicella-Zoster -- Prophylaxis:
0.5 mL intramuscularly
-Administer two doses, with the second dose given 2 to 6 months after the first dose
Comments:
-This drug is not indicated for prevention of primary varicella infection (chickenpox).
Use: Prevention of herpes zoster (shingles) in adults aged 50 years and older
Call your doctor if you miss the second dose or if you get behind schedule. You must receive all recommended doses of Shingrix to be fully protected against disease.
An overdose of Shingrix is unlikely to occur.
Follow your doctor's instructions about any restrictions on food, beverages, or activity.
You should not receive the second shot if you had a life-threatening allergic reaction after the first shot.
Keep track of any and all side effects you have after receiving zoster vaccine. When you receive the second shot, tell the doctor if the first shot caused any side effects.
Becoming infected with shingles is much more dangerous to your health than receiving the vaccine to protect against it. Like any medicine, this vaccine can cause side effects, but the risk of serious side effects is extremely low.
Get emergency medical help if you have signs of an allergic reaction to Shingrix: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have a high fever.
Common Shingrix side effects include:
headache, muscle pain;
feeling tired;
stomach pain, nausea, vomiting, diarrhea;
fever, shivering; or
pain, redness, or swelling where the shot was given.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report vaccine side effects to the US Department of Health and Human Services at 1-800-822-7967.
Other drugs may affect zoster vaccine, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Shingrix only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.
Source: Drugs.com Shingrix (www.drugs.com/shingrix.html).
Note: This document contains side effect information about zoster vaccine, inactivated. Some of the dosage forms listed on this page may not apply to the brand name Shingrix.
Applies to zoster vaccine, inactivated: intramuscular suspension
Along with its needed effects, zoster vaccine, inactivated (the active ingredient contained in Shingrix) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking zoster vaccine, inactivated:
Rare
Some side effects of zoster vaccine, inactivated may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
Less common
Applies to zoster vaccine, inactivated: intramuscular powder for injection
Very common (10% or more): Local pain (88.4%), local redness (38.7%)
Common (1% to 10%): Injection site pruritus
Very common (10% or more): Fatigue (57%), shivering (35.8%), fever (27.8%)
Common (1% to 10%): Malaise
Uncommon (0.1% to 1%): Death
Deaths were reported for 0.8% of patients in the treatment group during the first year after vaccination versus 0.9% of placebo patients. Causes of death were consistent with those generally reported in adult and elderly populations.
Very common (10% or more): Headache (50.6%)
Common (1% to 10%): Dizziness
Very common (10% or more): Gastrointestinal symptoms (24.3%)
Common (1% to 10%): Nausea
Uncommon (0.1% to 1%): Gout (including gouty arthritis)
Rare (less than 0.1%): Optic ischemic neuropathy
Very rare (less than 0.01%): Lymphadenitis
Very common (10% or more): Myalgia (56.9%)
Common (1% to 10%): Chills, arthralgia
Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.
Source: Drugs.com Shingrix (www.drugs.com/shingrix.html).
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