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Rocaltrol

Generic Name: Calcitriol Capsules (kal si TRYE ole)
Brand Name: Rocaltrol
Easy-to-read patient leaflet for Rocaltrol (Calcitriol Capsules). Includes indications, proper use, special instructions, precautions, and possible side effects.

Average Savings for calcitriol (generic): 28.08%
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Drug Information:
This is not a list of all drugs or health problems that interact with Rocaltrol (Calcitriol capsules). Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Rocaltrol (Calcitriol capsules) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor. Use Rocaltrol (Calcitriol capsules) as ordered by your doctor. Read all information given to you. Follow all instructions closely. Learn more

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Rocaltrol Side Effects

Note: This document contains side effect information about calcitriol. Some of the dosage forms listed on this page may not apply to the brand name Rocaltrol.

In Summary

Common side effects of Rocaltrol include: hypercalcemia, hypercalciuria, and increased serum creatinine. See below for a comprehensive list of adverse effects.

For the Consumer

Applies to calcitriol: oral capsules, oral solution, parenteral injection

Side effects include:

Excessive vitamin D intake (early manifestations): Weakness, headache, somnolence, nausea, dry mouth, constipation, muscle or bone pain, metallic taste, anorexia, abdominal pain, epigastric distress.

Excessive vitamin D intake (late manifestations): Polyuria, polydipsia, anorexia, weight loss, nocturia, calcific conjunctivitis, pancreatitis, photophobia, rhinorrhea, pruritus, hyperthermia, decreased libido, elevated BUN, albuminuria, hypercholesterolemia, elevated AST, elevated ALT, ectopic calcification, nephrocalcinosis, hypertension, cardiac arrhythmias, dystrophy, sensory disturbances, dehydration, apathy, arrested growth, urinary tract infections.

For Healthcare Professionals

Applies to calcitriol: injectable solution, oral capsule, oral liquid

General

Early signs of excessive vitamin D intake include weakness, headache, somnolence, nausea, vomiting, dry mouth, constipation, muscle pain, bone pain, metallic taste, anorexia, abdominal pain, or stomach ache. Late signs include polyuria, polydipsia, anorexia, weight loss, nocturia, conjunctivitis (calcific), pancreatitis, photophobia, rhinorrhea, pruritus, hyperthermia, decreased libido, elevated BUN, albuminuria, hypercholesterolemia, elevated AST and ALT, ectopic calcification, nephrocalcinosis, hypertension, cardiac arrhythmias, dystrophy, sensory disturbances, dehydration, apathy, arrested growth, urinary tract infections, and rarely, overt psychosis.

Adverse events were similar to those of excessive vitamin D intake, hypercalcemia syndrome or calcium intoxication.

Metabolic

Very common (10% or more): Hypercalcemia

Uncommon (0.1% to 1%): Decreased appetite

Frequency not reported: Polydipsia, dehydration, weight loss, thirst, hyperphosphatemia, anorexia, hypercholesterolemia

Genitourinary

Common (1% to 10%): Hypercalciuria, urinary tract infection

Frequency not reported: Polyuria, nocturia, albuminuria

Nervous system

Common (1% to 10%): Headache

Frequency not reported: Sensory disturbance, somnolence, metallic taste

Postmarketing reports: Seizure

Hypersensitivity

Frequency not reported: Allergic reaction, hypersensitivity (including rash, erythema, pruritus, and urticaria)

Postmarketing reports: Anaphylaxis

Gastrointestinal

Common (1% to 10%): Abdominal pain, nausea

Uncommon (0.1% to 1%): Vomiting

Frequency not reported: Constipation, abdominal pain upper, paralytic ileus, dry mouth, pancreatitis, epigastric discomfort, diarrhea

Dermatologic

Common (1% to 10%): Rash

Frequency not reported: Urticaria, erythema, pruritus, erythema multiforme

Cardiovascular

Frequency not reported: Cardiac arrhythmias, cardiac arrest, hypertension

Hepatic

Frequency not reported: Elevated AST, elevated ALT

Other

Frequency not reported: Calcinosis, pyrexia, weakness, hyperthermia, ectopic calcification, dystrophy

Postmarketing reports: Chest pain

Renal

Uncommon (0.1% to 1%): Blood creatinine increased

Frequency not reported: Elevated BUN, nephrocalcinosis, impairment of renal function

Musculoskeletal

Frequency not reported: Muscular weakness, growth retardation, muscle pain, bone pain

Psychiatric

Frequency not reported: Apathy, psychiatric disturbances, decreased libido, overt psychosis

Local

Frequency not reported: Pain on injection

Postmarketing reports: Bleeding at the venipuncture site

Hematologic

Postmarketing reports: Hemolysis

Oncologic

Postmarketing reports: Brown tumor, non-malignant tumor on the ribs

Ocular

Frequency not reported: Conjunctivitis (calcific), photophobia

Respiratory

Frequency not reported: Rhinorrhea

Editorial References and Review

Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.

Source: Drugs.com Rocaltrol (www.drugs.com/rocaltrol.html).