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Rivastigmine Transdermal

Rivastigmine transdermal Prescription
Generic Name: rivastigmine (oral) (ri va STIG meen)
Brand Name: Exelon
Physician reviewed rivastigmine (oral) patient information - includes rivastigmine description, dosage and directions.
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Rivastigmine Transdermal Drug Information:

Rivastigmine is used to treat mild to moderate dementia caused by Alzheimer's or Parkinson's disease. Rivastigmine is not a cure for Alzheimer's or Parkinson's disease. Rivastigmine may also be used for purposes not listed in this medication guide. You should not take oral rivastigmine if you have ever had severe redness, itching, or skin irritation caused by wearing a rivastigmine transdermal skin patch. You should not take rivastigmine if you are allergic to rivastigmine or similar medicines, such as Felbamate, Meprobamate, or Carisoprodol. Learn more

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Rivastigmine Transdermal Side Effects

In Summary

Commonly reported side effects of rivastigmine include: abdominal pain, diarrhea, dizziness, headache, nausea, vomiting, weight loss, and anorexia. Other side effects include: anxiety, asthenia, depression, drowsiness, dyspepsia, fatigue, tremor, diaphoresis, flatulence, and malaise. See below for a comprehensive list of adverse effects.

For the Consumer

Applies to rivastigmine: oral capsule

Other dosage forms:

  • transdermal patch extended release
Side effects requiring immediate medical attention

Along with its needed effects, rivastigmine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking rivastigmine:

More common

  • Diarrhea
  • indigestion
  • loss of appetite
  • loss of strength
  • nausea and vomiting
  • weight loss

Less common

  • Fainting

Rare

  • Aggression
  • convulsions (seizures)
  • trembling and shaking of the hands and fingers
  • trouble urinating

Incidence not known

  • Bloody or black, tarry stools
  • chest pain or discomfort
  • constipation
  • difficulty with speaking
  • drooling
  • lightheadedness, dizziness, or fainting
  • loss of balance control
  • muscle trembling, jerking, or stiffness
  • restlessness
  • severe stomach pain
  • shortness of breath
  • shuffling walk
  • slow or irregular heartbeat
  • stiffness of the limbs
  • trouble urinating
  • twisting movements of the body
  • uncontrolled movements, especially of the face, neck, and back
  • unusual tiredness
  • vomiting of blood or material that looks like coffee grounds

Get emergency help immediately if any of the following symptoms of overdose occur while taking rivastigmine:

Symptoms of overdose

  • Chest pain or discomfort
  • increased sweating
  • increased watering of the mouth
  • irregular, fast, slow, or shallow breathing
  • lightheadedness, dizziness, or fainting
  • nausea (severe)
  • pale or blue lips, fingernails, or skin
  • seizures
  • slow or irregular heartbeat
  • trouble breathing
  • unusual tiredness
  • vomiting (severe)
Side effects not requiring immediate medical attention

Some side effects of rivastigmine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Abdominal or stomach pain or cramping
  • bloated or full feeling
  • confusion
  • dizziness
  • headache
  • mental depression
  • seeing, hearing, or feeling things that are not there
  • trouble sleeping

Less common

  • General feeling of discomfort or illness
  • runny nose

For Healthcare Professionals

Applies to rivastigmine: oral capsule, oral solution, transdermal film extended release

Dermatologic

Common (1% to 10%): Hyperhidrosis

Rare (less than 0.1%): Rash

Frequency not reported: Pruritus

Postmarketing reports: Stevens-Johnson syndrome disseminated allergic dermatitis

Cardiovascular

Common (1% to 10%): Hypertension, bradycardia

Uncommon (0.1% to 1%): Hypotension

Rare (0.01% to 0.1%): Angina pectoris

Very rare (less than 0.01%): Cardiac arrhythmia (e.g., bradycardia, atrioventricular block, atrial fibrillation, tachycardia)

Frequency not reported: Sick sinus syndrome

Gastrointestinal

Very common (10% or more): Nausea (47%), vomiting (31%)diarrhea (19%), abdominal pain (13%)

Common (1% to 10%): Dyspepsia, salivary hypersecretion, upper abdominal pain, flatulence, eructation

Rare (0.01% to 0.1%): Gastric and duodenal ulcers

Very rare (less than 0.01%): GI hemorrhage, pancreatitis

Frequency not reported: Some cases of severe vomiting were associated with esophageal rupture

Genitourinary

Common (1% to 10%): Urinary incontinence

Very rare (less than 0.01%): Urinary tract infection

Hepatic

Frequency not reported: Elevated liver function tests, hepatitis

Nervous system

Very common (10% or more): Tremor (23%), dizziness (21%)

Common (1% to 10%): Somnolence, bradykinesia, dyskinesia, cogwheel rigidity, hypokinesia, vertigo, psychomotor hyperactivity, gait disturbance, Parkinson gait, headache

Uncommon (0.1% to 1%): Syncope, dystonia

Rare (0.01% to 0.1%): Seizures

Psychiatric

Common (1% to 10%): Insomnia, confusion, depression, anxiety, hallucination, agitation, restlessness, nightmares

Local

Common (1% to 10%): Application site erythema, application site irritation (e.g., pruritus, rash)

Postmarketing reports: Application site hypersensitivity, urticaria, blister, allergic dermatitis

Metabolic

Very common (10% or more): Anorexia (17%)

Common (1% to 10%): Decreased appetite

Frequency not reported: Dehydration

Other

Common (1% to 10%): Asthenia, weight loss, fatigue, malaise, fall

Respiratory

Common (1% to 10%): Rhinitis

Editorial References and Review

Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.

Source: Drugs.com Rivastigmine Transdermal (www.drugs.com/mtm/rivastigmine.html).