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Riboflavin

Riboflavin Prescription
Generic Name: riboflavin ophthalmic (RYE boe flay vin off THAL mik)
Brand Name: Photrexa, Photrexa Viscous, Photrexa-Photrexa Viscous Cross-Linking Kit
Physician reviewed riboflavin ophthalmic patient information - includes riboflavin ophthalmic description, dosage and directions.
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Riboflavin Drug Information:

Riboflavin (vitamin B2) is important in the maintenance of many tissues of the body. Riboflavin ophthalmic (for the eyes) is a "photosensitive" solution used during a procedure to treat progressive keratoconus in adults and adolescents who are at least 14 years old. Keratoconus (KER-a-toe-KOE-nus) is a degenerative eye disease that affects the cornea, the outermost layer on the surface of your eye. The cornea works by directing light toward the back of your eye to help you focus your vision. In people with keratoconus, the cornea becomes thin and weak, and then bulges outward. This causes incoming light to be channeled in too many directions, causing distorted vision. Progressive keratoconus can cause vision problems that may eventually lead to vision loss or a corneal transplant. Learn more

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Riboflavin Side Effects

For the Consumer

Applies to riboflavin ophthalmic: ophthalmic solution

Side effects requiring immediate medical attention

Along with its needed effects, riboflavin ophthalmic may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking riboflavin ophthalmic:

More common

  • Blindness
  • blurred vision
  • change in color vision
  • decreased vision
  • difficulty seeing at night
  • eye pain, irritation or redness, or inflammation
  • feeling of having something in the eye
  • increased sensitivity of the eyes to sunlight
  • painful irritation of the clear front part of the eye

Less common

  • Drainage from the eyes
  • eye discomfort
  • seeing flashes or sparks of light
  • seeing floating spots before the eyes, or a veil or curtain appearing across part of vision
  • sensitivity of the eyes to light
Side effects not requiring immediate medical attention

Some side effects of riboflavin ophthalmic may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Dry eyes
  • headache

Less common

  • Double vision
  • redness, swelling, or itching of the eyelid
  • seeing double
  • watering of the eyes

For Healthcare Professionals

Applies to riboflavin ophthalmic: ophthalmic solution

General

The most commonly reported side effects include corneal opacity, punctate keratitis, corneal striae and corneal epithelium defect.

Ocular

Very common (10% or more): Corneal opacity/haze (up to 71%), corneal epithelium defect (up to 28%), eye pain (up to 26%), punctate keratitis (up to 25%), corneal striae (up to 24%), photophobia (up to 19%), blurred vision (up to 17%), foreign body sensation in eyes (up to 15%), dry eye (up to 14%), ocular hyperemia (up to 14%), reduced visual acuity (up to 11%)

Common (1% to 10%): Anterior chamber cell, anterior chamber flare, corneal disorder, asthenopia, corneal edema, diplopia, eye discharge, eye edema, eye pruritus, eyelid edema, glare, halo vision, keratitis, increased lacrimation, Meibomian gland dysfunction, ocular discomfort, visual impairment, vitreous detachment

Frequency not reported: Blepharitis, corneal thinning

Nervous system

Common (1% to 10%): Headache

Other

Common (1% to 10%): Eye complication associated with device

Editorial References and Review

Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.

Source: Drugs.com Riboflavin (www.drugs.com/mtm/riboflavin-ophthalmic.html).