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Note: This document contains side effect information about evolocumab. Some of the dosage forms listed on this page may not apply to the brand name Repatha.
For the ConsumerApplies to evolocumab: subcutaneous solution
Along with its needed effects, evolocumab (the active ingredient contained in Repatha) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking evolocumab:
Incidence not known
Some side effects of evolocumab may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
Less common
For Healthcare Professionals
Applies to evolocumab: subcutaneous solution
GeneralThe more commonly reported adverse reactions have included nasopharyngitis, upper respiratory tract infection, back pain, and injection site reactions.
HypersensitivityCommon (1% to 10%): Hypersensitivity reactions (including rash, eczema, erythema, urticaria)
Postmarketing reports: Angioedema
CardiovascularCommon (1% to 10%): Hypertension
GastrointestinalCommon (1% to 10%): Diarrhea, gastroenteritis, nausea (1.8%)
GenitourinaryCommon (1% to 10%): Urinary tract infection
LocalCommon (1% to 10%): Injection site reaction (including erythema, pain, bruising)
MusculoskeletalCommon (1% to 10%): Back pain, myalgia, musculoskeletal pain, arthralgia (1.8%)
Nervous systemCommon (1% to 10%): Headache, dizziness
Uncommon (0.1% to 1%): Neurocognitive events (0.2%)
OtherCommon (1% to 10%): Influenza, fatigue (1.6%)
Uncommon (0.1% to 1%): Contusion
RespiratoryCommon (1% to 10%): Influenza, fatigue (1.6%)
Uncommon (0.1% to 1%): Contusion
ImmunologicRare (less than 0.1%): Development anti-drug antibody
Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/3/2022.
Source: Drugs.com Repatha (www.drugs.com/repatha.html).
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