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Repatha

Generic Name: evolocumab (E voe LOK ue mab)
Brand Names: Repatha
Repatha (evolocumab) is a PCSK9 inhibitor used to treat hypercholesterolemia (high cholesterol). Includes Repatha side effects, interactions and indications.
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Drug Information:
Repatha (evolocumab) is a human monoclonal antibody. It works by helping the liver reduce levels of "bad" Cholesterol (low-density lipoprotein, or LDL) circulating in your blood. Repatha is used together with a low-fat diet and other Cholesterol-lowering medications in people with homozygous or heterozygous familial hyperCholesterolemia (inherited types of high Cholesterol). These conditions can cause high blood levels of LDL Cholesterol, and can also cause plaque to build up inside your arteries. Learn more

Repatha Medicare Coverage

Overview

Does Medicare cover Repatha?

Yes

74% of Medicare Part D and Medicare Advantage plans cover this drug.
How much is my Repatha co-pay with Medicare?

It depends. Which coverage stage are you in? Click on a tab below…

CO-PAY RANGE

$518 – $1202

In the Deductible co-pay stage, you are responsible for the full cost of your prescriptions. Your Medicare deductible cannot exceed $360 in 2016.

Ways to Save on Repatha

Here are some ways that may lower the cost of your repatha prescription.

  • Instead of Medicare, Use a USA Rx Coupon

    If your Medicare co-pay is higher, you can save money by using a USARx coupon instead.

Repatha Side Effects

Repatha Side Effects

Note: This document contains side effect information about evolocumab. Some of the dosage forms listed on this page may not apply to the brand name Repatha.

For the Consumer

Applies to evolocumab: subcutaneous solution

Along with its needed effects, evolocumab (the active ingredient contained in Repatha) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking evolocumab:

Incidence not known

  • Difficulty with breathing or swallowing
  • fever
  • hives, itching, or rash
  • nausea
  • reddening of the skin, especially around the ears
  • swelling of the eyes, face, or inside of the nose
  • unusual tiredness or weakness

Some side effects of evolocumab may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Back pain
  • bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
  • blurred vision
  • body aches or pain
  • chills
  • cough
  • dry mouth
  • ear congestion
  • flushed, dry skin
  • fruit-like breath odor
  • headache
  • loss of voice
  • muscle aches
  • sneezing
  • sore throat
  • stomach ache
  • stuffy or runny nose
  • sweating
  • troubled breathing
  • unexplained weight loss
  • vomiting

Less common

  • Bladder pain
  • bloody or cloudy urine
  • diarrhea
  • difficult, burning, or painful urination
  • difficulty with moving
  • dizziness
  • frequent urge to urinate
  • loss of appetite
  • lower back or side pain
  • muscle or joint pain
  • muscle stiffness
  • nervousness
  • pain or tenderness around the eyes and cheekbones
  • pounding in the ears
  • slow or fast heartbeat
  • swollen joints

For Healthcare Professionals

Applies to evolocumab: subcutaneous solution

General

The more commonly reported adverse reactions have included nasopharyngitis, upper respiratory tract infection, back pain, and injection site reactions.

Hypersensitivity

Common (1% to 10%): Hypersensitivity reactions (including rash, eczema, erythema, urticaria)

Postmarketing reports: Angioedema

Cardiovascular

Common (1% to 10%): Hypertension

Gastrointestinal

Common (1% to 10%): Diarrhea, gastroenteritis, nausea (1.8%)

Genitourinary

Common (1% to 10%): Urinary tract infection

Local

Common (1% to 10%): Injection site reaction (including erythema, pain, bruising)

Musculoskeletal

Common (1% to 10%): Back pain, myalgia, musculoskeletal pain, arthralgia (1.8%)

Nervous system

Common (1% to 10%): Headache, dizziness

Uncommon (0.1% to 1%): Neurocognitive events (0.2%)

Other

Common (1% to 10%): Influenza, fatigue (1.6%)

Uncommon (0.1% to 1%): Contusion

Respiratory

Common (1% to 10%): Influenza, fatigue (1.6%)

Uncommon (0.1% to 1%): Contusion

Immunologic

Rare (less than 0.1%): Development anti-drug antibody

Editorial References and Review

Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.

Source: Drugs.com Repatha (www.drugs.com/repatha.html).