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Questran

Generic Name: cholestyramine (koe le STYE ra meen)
Brand Name: Cholestyramine Light, Prevalite, Questran
Physician reviewed Questran patient information - includes Questran description, dosage and directions.

Average Savings for cholestyramine (generic): 15.02%
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Drug Information:
Questran helps reduce Cholesterol (fatty acids) in the blood. High Cholesterol is associated with an increased risk of heart disease and atherosclerosis (clogged arteries). Questran is used to lower high levels of Cholesterol in the blood, especially low-density lipoprotein (LDL) ("bad" Cholesterol). Questran powder is also used to treat itching caused by a blockage in the bile ducts of the gallbladder. Questran may also be used for purposes not listed in this medication guide. You should not use Questran if you have a blockage in your stomach or intestines. Learn more

Questran Side Effects

Questran Side Effects

Note: This document contains side effect information about cholestyramine. Some of the dosage forms listed on this page may not apply to the brand name Questran.

In Summary

More frequent side effects include: constipation, dyspepsia, heartburn, nausea, stomach pain, and vomiting. See below for a comprehensive list of adverse effects.

For the Consumer

Applies to cholestyramine: oral powder for suspension

In some animal studies, cholestyramine (the active ingredient contained in Questran) was found to cause tumors. It is not known whether cholestyramine causes tumors in humans.

Along with its needed effects, cholestyramine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking cholestyramine:

Rare

  • Black, tarry stools
  • stomach pain (severe) with nausea and vomiting

Check with your doctor as soon as possible if any of the following side effects occur while taking cholestyramine:

More common

  • Constipation

Rare

  • Loss of weight (sudden)

Some side effects of cholestyramine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Heartburn or indigestion
  • nausea or vomiting
  • stomach pain

Less common

  • Belching
  • bloating
  • diarrhea
  • dizziness
  • headache

For Healthcare Professionals

Applies to cholestyramine: compounding powder, oral powder for reconstitution

General

The most frequently reported side effect is constipation.

Gastrointestinal

Intestinal obstruction occurred rarely and 2 deaths in pediatric patients were reported.

Very common (10% or more): Constipation

Uncommon (0.1% to 1%): Tongue irritation, irritation of perianal area, abdominal discomfort/pain/distention, flatulence, nausea, vomiting, diarrhea, heartburn, dyspepsia, steatorrhea

Rare (less than 0.1%): Intestinal obstruction

Frequency not reported: Rectal bleeding, black stools, hemorrhoidal bleeding, bleeding from known duodenal ulcer, dysphagia, hiccoughs, ulcer attack, sour taste, pancreatitis, rectal pain, diverticulitis, eructation, dental bleeding, dental caries, calcification of gallbladder, tooth discoloration, erosion of tooth enamel

Cardiovascular

Frequency not reported: Claudication, angina, arteritis, thrombophlebitis, myocardial infarction, myocardial ischemia, postprandial angina increased

Musculoskeletal

Common (1% to 10%): Osteoporosis

Frequency not reported: Backache, arthritis, muscle/joint pain

Hematologic

Uncommon (0.1% to 1%): Bleeding

Frequency not reported: Prothrombin time increased, prothrombin time decreased, anemia, hypoprothrombinemia

Metabolic

Uncommon (0.1% to 1%): Anorexia, hyperchloremic acidosis, Vitamin A deficiency, Vitamin K deficiency

Dermatologic

Uncommon (0.1% to 1%): Rash, skin irritation

Frequency not reported: Ecchymosis, xanthoma of hands/fingers, urticaria

Hepatic

Frequency not reported: Liver function test abnormal

Nervous system

Frequency not reported: Headache, paresthesia, syncope, dizziness, drowsiness, femoral nerve pain

Other

Frequency not reported: Vertigo, weight loss, weight gain, glands swollen, edema, chest pain, tinnitus

Ocular

Frequency not reported: Arcus juvenilis, uveitis, night blindness

Genitourinary

Frequency not reported: Hematuria, dysuria, burnt odor to urine, diuresis

Respiratory

Frequency not reported: Asthma, wheezing, shortness of breath

Psychiatric

Frequency not reported: Libido increased

Editorial References and Review

Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.

Source: Drugs.com Questran (www.drugs.com/mtm/questran.html).