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Quelicin

Generic Name: Succinylcholine (suks in il KOE leen)
Brand Name: Anectine, Quelicin
Easy-to-read patient leaflet for Quelicin. Includes indications, proper use, special instructions, precautions, and possible side effects.
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Drug Information:
This is not a list of all drugs or health problems that interact with Quelicin (succinylcholine). Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Quelicin (succinylcholine) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor. Use Quelicin (succinylcholine) as ordered by your doctor. Read all information given to you. Follow all instructions closely. Learn more

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Quelicin Side Effects

Note: This document contains side effect information about succinylcholine. Some of the dosage forms listed on this page may not apply to the brand name Quelicin.

For the Consumer

Applies to succinylcholine: parenteral injection

Warning

    Rhabdomyolysis with Hyperkalemia
  • Risk of acute rhabdomyolysis with hyperkalemia followed by ventricular arrhythmias, cardiac arrest, and death in apparently healthy children and adolescents who subsequently were found to have undiagnosed skeletal muscle myopathy (e.g., Duchenne’s muscular dystrophy).

  • Use in children and adolescents should be reserved for those undergoing emergency intubation, those in whom an airway should be secured immediately (e.g., patients with laryngospasm, difficult airway, or full stomach), or those in whom a suitable vein is not accessible and IM administration is needed. (See Pediatric Use under Cautions.)

    Experience of Clinician
  • Should be administered only by individuals experienced in the use of neuromuscular blocking agents.

Side effects include:

Various degrees of skeletal muscle weakness.

For Healthcare Professionals

Applies to succinylcholine: compounding powder, injectable powder for injection, injectable solution, intravenous solution

Hypersensitivity

Very rare (less than 0.01%): Anaphylaxis

Musculoskeletal

Very common (10% or more): Muscle fasciculation, post-operative muscle pain

Common (1% to 10%): Myoglobinemia, myoglobinuria

Rare (less than 0.1%): Trismus

Frequency not reported: Rhabdomyolysis, myoglobinuria, myoglobinemia, elevated creatine phosphokinase, hypertonia, precipitation or exacerbation of myasthenia gravis

Ocular

Common (1% to 10%): Increased intraocular pressure

Metabolic

Common (1% to 10%): Hyperkalemia

Respiratory

Rare (0.01% to 0.1%): Bronchospasm, prolonged respiratory depression, apnea

Very rare (less than 0.01%): Increased bronchial secretions, pulmonary edema (in infants)

Other

Very rare (less than 0.01%): Malignant hyperthermia, porphyria

Renal

Frequency not reported: Renal failure

Cardiovascular

Common (1% to 10%): Bradycardia, tachycardia, flushing, hypertension, hypotension

Rare (less than 0.1%): Arrhythmias (including ventricular arrhythmia), cardiac arrest, hyperkalemia-related cardiac arrest (following administration to patients with congenital cerebral palsy, tetanus, Duchenne muscular dystrophy, and closed head injury)

Frequency not reported: Circulatory collapse, shock

Dermatologic

Common (1% to 10%): Rash

Gastrointestinal

Very common (10% or more): Increased intragastric pressure, excessive salivation

Frequency not reported: Increased bowel movements, increased gastric secretions

Editorial References and Review

Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.

Source: Drugs.com Quelicin (www.drugs.com/cdi/quelicin.html).