Loading

Please wait...

Propofol

Propofol Prescription
Generic Name: propofol (PROE poe fol)
Brand Names: Diprivan, Propoven
Propofol (Diprivan) is used to induce or maintain anesthesia during certain surgeries, tests, or procedures. Includes propofol side effects, interactions and indications
  • Prescription Settings
  • X
  • medly Free, same-day prescription delivery to your doorstep is available in your area.
  • Learn more
  • Local Pharmacy Pickup available at . Pick up your medication at any of our participating pharmacies.
  • Mail Order Home Delivery available at , the easiest way to receive your medications.

Propofol Coupons & Prices

Set your location
for drug prices near you

Enter your zip code

Please wait while the prices are loaded...
Click here to try again.

Don’t see your pharmacy listed? Most pharmacies accept our discounts, so have your pharmacist enter this coupon to see if you will save money:

Propofol Drug Information:

Propofol (Diprivan) slows the activity of your brain and nervous system. Propofol is used to put you to sleep and keep you asleep during general anesthesia for surgery or other medical procedures. It is used in adults as well as children 2 months and older. Propofol is also used to sedate a patient who is under critical care and needs a mechanical ventilator (breathing machine). Before you receive propofol, tell your doctor about all your medical conditions and allergies. Also make sure your doctor knows if you are pregnant or breast-feeding. In some cases, you may not be able to use propofol. Learn more

Buy Propofol Online and Propofol Delivery

USARx offers the following ways to purchase this medication. Choose the Best option for you!

  • Guaranteed Price

    Local Pharmacy Pickup of Propofol

    Pay this amount and pick up your prescription at ANY Retail pharmacy of your choice! Walgreens, CVS, Walmart, etc.

  • 30-day supply
    90-day supply

    Mail Order Home Delivery of Propofol

    The easiest way to receive your medications.

Propofol Side Effects

For the Consumer

Applies to propofol: parenteral injectable emulsion

Warning

    Microbial Contamination
  • Propofol injectable emulsion can support microbial growth. (See Potential for Microbial Contamination under Cautions.)

  • Use strict aseptic technique at all times during handling; failure to use aseptic technique may result in microbial contamination and possible fever, infection/sepsis, other life-threatening illness, and/or death.

  • Discard unused portions within the required time limits. (See Stability and Sterility Considerations under Dosage and Administration.)

  • Do not use if contamination is suspected.

Side effects include:

Use for anesthesia or MAC sedation: Bradycardia, arrhythmia, tachycardia, hypotension, hypertension, movement, burning/stinging, pain at injection site, apnea, rash, pruritus.

Use for critical care setting sedation: Bradycardia, decreased cardiac output, hypotension, hyperlipidemia, respiratory acidosis (during weaning).

For Healthcare Professionals

Applies to propofol: intravenous emulsion

Cardiovascular

Very common (10% or more): Hypotension (75%)

Common (1% to 10%): Hypertension, bradycardia

Uncommon (0.1% to 1%): Arrhythmias, atrial fibrillation, atrioventricular heart block, bigeminy, bundle branch block, cardiac arrest, ECG abnormal, edema, extrasystole, heart block, myocardial infarction, myocardial ischemia, premature ventricular contractions, ST segment depression, supraventricular tachycardia, tachycardia, ventricular fibrillation, extrasystole, syncope, chest pain, right heart failure

Rare (0.01% to 0.1%): Pulmonary edema, asystole, syncope, perioperative arrhythmias, cardiac arrest

Very rare (less than 0.01%): Cardiac failure

Frequency not reported: Cardiac arrhythmia

Dermatologic

Very common (10% or more): Pruritus (28%)

Common (1% to 10%): Transient flush, rash

Uncommon (0.1% to 1%): Conjunctival hyperemia, diaphoresis, urticaria

Gastrointestinal

Common (1% to 10%): Nausea, vomiting

Uncommon (0.1% to 1%): Hypersalivation, cramping, diarrhea, dry mouth, enlarged parotid, nausea, impaired swallowing, vomiting, ileus

Very rare (less than 0.01%): Pancreatitis, abdominal cramps

Genitourinary

Uncommon (0.1% to 1%): Urinary retention oliguria

Rare (Less than 0.1%): Discoloration of the urine following prolonged use

Hepatic

Frequency not reported: Hepatomegaly

Hypersensitivity

Rare (0.01% to 0.1%): Anaphylaxis, in some cases with angioedema, bronchospasm, erythema, and hypotension (these reactions have been reported to respond to adrenaline)

Local

Common (1% to 10%): Pain during injection (e.g., burning, tingling/slinging)

Very rare (less than 0.01%): Tissue necrosis following accidental extravascular administration

Uncommon (0.1% to 1%): Hives/itching, phlebitis, redness/discoloration

Metabolic

Uncommon (0.1% to 1%): BUN Increased, creatinine increased, dehydration, hyperglycemia, metabolic acidosis, osmolality increased

Very rare (less than 0.01%): Metabolic acidosis, hyperkalemia, hyperlipidemia

Musculoskeletal

Uncommon (0.1% to 1%): Pain in extremities, trunk pain, whole body weakness, pain in extremities, neck rigidity/stiffness

Very rare (less than 0.01%): Rhabdomyolysis (when administered at doses greater than 4 mg/kg/hour for ICU sedation)

Nervous system

Paresthesias (including burning, tingling, stinging) and/or pruritus, usually manifested in the perineal region, were the most frequently recorded adverse reactions in clinical trials. Paresthesias and pruritus generally occurred within 5 minutes after administration of the initial dose and were generally transient and mild to moderate in intensity. The pharmacologic basis of these sensory phenomena is unknown. No pretreatments, including the use of nonsteroidal anti-inflammatory drugs, opioids, or lidocaine, are known to have an effect on or to reduce the incidence of these sensations.

Very common (10% or more): Paresthesia (74%), excitation phenomena such as involuntary movements, twitches, tremors, hypertonus, hiccup

Common (1% to 10%): Headache, shivering

Rare (0.01% to 0.1%): Convulsions and seizures of the epileptic type

Very rare (less than 0.01%): Postoperative unconsciousness

Frequency not reported: Involuntary movements

Respiratory

Very common (10% or more): Hypoxemia (11%)

Common (1% to 10%): Procedural pain (bronchoscopy), transient apnea, cough, respiratory acidosis during weaning

Uncommon (0.1% to 1%): Bronchospasm, burning in throat, cough, dyspnea, hiccough, hyperventilation, hypoventilation, hypoxia, laryngospasm, pharyngitis, sneezing, tachypnea, upper airway obstruction, apnea

Very rare (less than 0.01%): Pulmonary edema

Renal

Very rare (less than 0.01%): Renal failure

Hematologic

Common (1% to 10%): Thrombosis, phlebitis

Uncommon (0.1% to 1%): Hemorrhage, coagulation disorder, leukocytosis

Immunologic

Uncommon (0.1% to 1%): Sepsis

Ocular

Uncommon (0.1% to 1%): Diplopia, eye pain, nystagmus

Psychiatric

Common (1% to 10%): Elation/euphoria

Frequency not reported: Drug abuse and dependence

Other

Uncommon (0.1% to 1%): Fever, anticholinergic syndrome, ear pain, taste perversion, tinnitus

Editorial References and Review

Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.

Source: Drugs.com Propofol (www.drugs.com/propofol.html).