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Note: This document contains side effect information about hydrocortisone topical. Some of the dosage forms listed on this page may not apply to the brand name Proctocort.
For the ConsumerApplies to hydrocortisone topical: topical application cream, topical application gel/jelly, topical application liquid, topical application lotion, topical application ointment, topical application solution, topical application spray
Other dosage forms:
Along with its needed effects, hydrocortisone topical (the active ingredient contained in Proctocort) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking hydrocortisone topical:
Incidence not known
Some side effects of hydrocortisone topical may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Incidence not known
For Healthcare Professionals
Applies to hydrocortisone topical: compounding powder, rectal cream with applicator, rectal foam, rectal ointment, rectal solution, rectal suppository, topical cream, topical gel, topical kit, topical lotion, topical ointment, topical pad, topical paste, topical solution, topical spray, topical stick
GeneralThe most commonly reported side effects were burning, itching, irritation, dryness, and folliculitis.
CardiovascularFrequency not reported: Bradycardia, cardiac arrest, cardiac arrhythmias, cardiac enlargement, circulatory collapse, congestive heart failure, fat embolism, hypertension, hypertrophic cardiomyopathy in premature infants, myocardial rupture following recent myocardial infarction, syncope, tachycardia, thromboembolism, thrombophlebitis, vasculitis
EndocrineFrequency not reported: HPA axis suppression, decreased carbohydrate and glucose tolerance, development of cushingoid state, glycosuria, hirsutism, hypertrichosis, increased requirements for insulin or oral hypoglycemic agents in diabetes, manifestations of latent diabetes mellitus, menstrual irregularities, secondary adrenocortical and pituitary unresponsiveness (particularly in times of stress, as in trauma, surgery, or illness), suppression of growth in pediatric patients
ImmunologicFrequency not reported: Decreased resistance to infection, concomitant skin infections
OcularFrequency not reported: Exophthalmos, glaucoma, increased intraocular pressure, posterior subcapsular cataracts, rare instances of blindness associated with periocular injections
PsychiatricFrequency not reported: Depression, emotional instability, euphoria, insomnia, mood swings, personality changes, psychic disorders
LocalFrequency not reported: Burning, itching, irritation, dryness, folliculitis
GastrointestinalFrequency not reported: Abdominal distention, nausea, pancreatitis, peptic ulcer with possible perforation and hemorrhage, perforation of the small and large intestine (particularly in patients with inflammatory bowel disease), ulcerative esophagitis
MusculoskeletalFrequency not reported: Aseptic necrosis of femoral and humeral heads, Charcot-like arthropathy, loss of muscle mass, muscle weakness, osteoporosis, pathologic fracture of long bones, steroid myopathy, tendon rupture, vertebral compression fractures
HypersensitivityFrequency not reported: Anaphylactoid reaction, anaphylaxis, angioedema
RespiratoryFrequency not reported: Pulmonary edema
DermatologicFrequency not reported: Acne, allergic dermatitis, cutaneous and subcutaneous atrophy, dry scaly skin, ecchymoses and petechiae, edema, erythema, hyperpigmentation, hypopigmentation, impaired wound healing, increased sweating, rash, sterile abscess, striae, suppressed reactions to skin tests, thin fragile skin, thinning scalp hair, urticaria, miliaria, telangiectasia
MetabolicFrequency not reported: Fluid retention, hypokalemic alkalosis, potassium loss, sodium retention, negative nitrogen balance due to protein catabolism, increased appetite, weight gain
HepaticFrequency not reported: Elevation in serum liver enzyme levels (usually reversible upon discontinuation), hepatomegaly
Nervous systemFrequency not reported: Convulsions, headache, increased intracranial pressure with papilledema (pseudotumor cerebri) usually following discontinuation of treatment, neuritis, neuropathy, vertigo
OtherFrequency not reported: Abnormal fat deposits, hiccups, increased or decreased motility and number of spermatozoa, malaise
Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/3/2022.
Source: Drugs.com Proctocort (www.drugs.com/mtm/proctocort-cream-ointment-suppository.html).
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