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Prevalite helps reduce cholesterol (fatty acids) in the blood. High cholesterol is associated with an increased risk of heart disease and atherosclerosis (clogged arteries).
Prevalite is used to lower high levels of cholesterol in the blood, especially low-density lipoprotein (LDL) ("bad" cholesterol).
Prevalite powder is also used to treat itching caused by a blockage in the bile ducts of the gallbladder.
Prevalite may also be used for purposes not listed in this medication guide.
You should not use Prevalite if you have a blockage in your stomach or intestines.
Wait at least 4 to 6 hours after taking Prevalite before you take any other medications.
You should not use Prevalite if you are allergic to it, or if you have:
a blockage in your digestive tract (stomach or intestines).
To make sure Prevalite is safe for you, tell your doctor if you have:
chronic constipation;
a thyroid disorder;
diabetes;
kidney disease;
liver disease; or
coronary artery disease (clogged arteries).
This medicine may contain phenylalanine. Talk to your doctor before using Prevalite if you have phenylketonuria (PKU).
Taking Prevalite can make it harder for your body to absorb certain vitamins. Your doctor may recommend you take a vitamin supplement.
You may have an even greater need for vitamin supplements during pregnancy or while you are breast-feeding a baby. Follow your doctor's instructions about taking vitamin supplements during treatment with Prevalite.
It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
Follow all directions on your prescription label. Your doctor may occasionally change your dose. Do not use Prevalite in larger or smaller amounts or for longer than recommended.
Although Prevalite is usually taken once or twice per day, this medicine may be taken up to 6 times per day. Carefully follow your doctor's dosing instructions.
Mix the Prevalite powder with at least 2 to 3 ounces of water or other non-carbonated beverage. You may also mix the powder with a brothy soup, crushed pineapple, or applesauce. Measure the powder using the scoop provided with your medication. Do not use any other scoop or measuring cup to measure your this medicine dose.
Prevalite works best if you take it with meals. However, your dosing schedule may depend on when you need to take any other medications. This medicine should not be taken within 1 hour after or 4 hours before you take other medications.
Use Prevalite regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.
Prevalite can affect the surfaces of your teeth. Sipping the this medicine/liquid mixture slowly or holding the liquid in your mouth for too long may result in tooth discoloration, enamel erosion, or tooth decay. Be sure to brush your teeth regularly while you are using this medicine.
Drink extra fluids to prevent constipation while you are taking Prevalite.
While using Prevalite, you may need frequent blood tests.
Prevalite is only part of a complete program of treatment that may also include diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely.
Store at room temperature away from moisture and heat.
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Overdose symptoms may include severe stomach pain or constipation.
Avoid taking other medications at the same time you take Prevalite. Wait at least 4 to 6 hours after taking this medicine before you take any other medications.
Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
ongoing or worsening constipation;
severe stomach pain;
blood in your urine;
black, bloody, or tarry stools; or
easy bruising, unusual bleeding.
Side effects such as constipation may be more likely in older adults.
Common side effects may include:
mild constipation, diarrhea;
stomach pain, nausea, loss of appetite;
bloating or gas;
irritation of your tongue; or
itching or irritation around your rectal area.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Tell your doctor about all your current medicines and any you start or stop using, especially:
birth control pills or hormone replacement therapy;
digoxin (digitalis);
a diuretic or "water pill";
penicillin G;
phenobarbital;
phenylbutazone;
propranolol;
spironolactone;
tetracycline;
thyroid medication such as levothyroxine (Synthroid and others); or
warfarin (Coumadin, Jantoven).
This list is not complete. Other drugs may interact with cholestyramine, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.
Source: Drugs.com Prevalite (www.drugs.com/mtm/prevalite.html).
Note: This document contains side effect information about cholestyramine. Some of the dosage forms listed on this page may not apply to the brand name Prevalite.
Applies to cholestyramine: oral powder for suspension
In some animal studies, cholestyramine (the active ingredient contained in Prevalite) was found to cause tumors. It is not known whether cholestyramine causes tumors in humans.
Along with its needed effects, cholestyramine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking cholestyramine:
Rare
Check with your doctor as soon as possible if any of the following side effects occur while taking cholestyramine:
More common
Rare
Some side effects of cholestyramine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
Less common
Applies to cholestyramine: compounding powder, oral powder for reconstitution
The most frequently reported side effect is constipation.
Intestinal obstruction occurred rarely and 2 deaths in pediatric patients were reported.
Very common (10% or more): Constipation
Uncommon (0.1% to 1%): Tongue irritation, irritation of perianal area, abdominal discomfort/pain/distention, flatulence, nausea, vomiting, diarrhea, heartburn, dyspepsia, steatorrhea
Rare (less than 0.1%): Intestinal obstruction
Frequency not reported: Rectal bleeding, black stools, hemorrhoidal bleeding, bleeding from known duodenal ulcer, dysphagia, hiccoughs, ulcer attack, sour taste, pancreatitis, rectal pain, diverticulitis, eructation, dental bleeding, dental caries, calcification of gallbladder, tooth discoloration, erosion of tooth enamel
Frequency not reported: Claudication, angina, arteritis, thrombophlebitis, myocardial infarction, myocardial ischemia, postprandial angina increased
Common (1% to 10%): Osteoporosis
Frequency not reported: Backache, arthritis, muscle/joint pain
Uncommon (0.1% to 1%): Bleeding
Frequency not reported: Prothrombin time increased, prothrombin time decreased, anemia, hypoprothrombinemia
Uncommon (0.1% to 1%): Anorexia, hyperchloremic acidosis, Vitamin A deficiency, Vitamin K deficiency
Uncommon (0.1% to 1%): Rash, skin irritation
Frequency not reported: Ecchymosis, xanthoma of hands/fingers, urticaria
Frequency not reported: Liver function test abnormal
Frequency not reported: Headache, paresthesia, syncope, dizziness, drowsiness, femoral nerve pain
Frequency not reported: Vertigo, weight loss, weight gain, glands swollen, edema, chest pain, tinnitus
Frequency not reported: Arcus juvenilis, uveitis, night blindness
Frequency not reported: Hematuria, dysuria, burnt odor to urine, diuresis
Frequency not reported: Asthma, wheezing, shortness of breath
Frequency not reported: Libido increased
Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.
Source: Drugs.com Prevalite (www.drugs.com/mtm/prevalite.html).
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