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Prevacid Prescription
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Generic Name: lansoprazole (lan SOE pra zol)
Brand Names: FIRST Lansoprazole, Prevacid
Prevacid is used to treat and prevent stomach and intestinal ulcers. Learn about side effects, interactions and indications. Average Savings for lansoprazole (generic): 78.92%
Generic Name: lansoprazole (lan SOE pra zol)
Brand Names: FIRST Lansoprazole, Prevacid
Prevacid is used to treat and prevent stomach and intestinal ulcers. Learn about side effects, interactions and indications. Average Savings for lansoprazole (generic): 78.92%
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30 tablets of Prevacid 40 mg
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Prevacid Drug Information:

Prevacid (Lansoprazole) is a proton pump inhibitor. Lansoprazole decreases the amount of acid produced in the stomach. Prevacid is used to treat and prevent stomach and intestinal ulcers, erosive esophagitis (damage to the esophagus from stomach acid), and other conditions involving excessive stomach acid such as Zollinger-Ellison syndrome. Prevacid OTC (over-the-counter) is used to treat frequent heartburn that happens 2 or more days per week. Prevacid is not for immediate relief of heartburn symptoms. Learn more

Prevacid Medicare Coverage

Prevacid Medicare Overview

Does Medicare cover Prevacid?


83% of Medicare Part D and Medicare Advantage plans cover this drug.
How much is my Prevacid co-pay with Medicare?

It depends. Which coverage stage are you in? Click on a tab below…


$7 – $64

In the Deductible co-pay stage, you are responsible for the full cost of your prescriptions. Your Medicare deductible cannot exceed $360 in 2016.

Ways to Save on Prevacid

Here are some ways that may lower the cost of your prevacid prescription.

  • Instead of Medicare, Use a USA Rx Coupon

    If your Medicare co-pay is higher, you can save money by using a USARx coupon instead.

Prevacid Side Effects

Note: This document contains side effect information about lansoprazole. Some of the dosage forms listed on this page may not apply to the brand name Prevacid.

For the Consumer

Applies to lansoprazole: oral capsule delayed release, oral powder for suspension, oral tablet disintegrating delayed release

Along with its needed effects, lansoprazole (the active ingredient contained in Prevacid) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking lansoprazole:

More common

  • Diarrhea
  • itching, skin rash

Less common

  • Increased or decreased appetite
  • joint pain
  • nausea
  • stomach pain
  • vomiting


  • Anxiety
  • colds
  • constipation
  • increased cough
  • mental depression
  • muscle pain
  • rectal bleeding
  • unusual bleeding or bruising

Incidence not known

  • Back or leg pains
  • bleeding gums
  • blistering, peeling, or loosening of the skin
  • bloating
  • bloody, black, or tarry stools
  • change in mental status
  • chest pain
  • chills
  • clay colored stools
  • cough
  • dark or bloody urine
  • difficulty with swallowing
  • drowsiness
  • fast heartbeat
  • fever
  • general body swelling
  • high fever
  • hives
  • hoarseness
  • indigestion
  • loss of appetite
  • lower back or side pain
  • mood or mental changes
  • muscle spasms (tetany) or twitching seizures
  • nosebleeds
  • painful or difficult urination
  • pains in the stomach, side, or abdomen, possibly radiating to the back
  • pale skin
  • pinpoint red spots on the skin
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • red skin lesions, often with a purple center
  • red, irritated eyes
  • seizures
  • sore throat
  • sores, ulcers, or white spots on the lips or in the mouth
  • stomach tenderness
  • swelling of the feet or lower legs
  • swollen or painful glands
  • tightness in the chest
  • trembling
  • unusual tiredness or weakness
  • yellow eyes or skin

Some side effects of lansoprazole may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Dizziness
  • headache

Less common

  • Bleeding, blistering, burning, coldness, or discoloration of the skin
  • mild nausea


  • Bad, unusual, or unpleasant (after) taste
  • belching
  • burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  • change in taste
  • feeling of heat or warmth
  • flushing or redness of the skin, especially on the face and neck
  • mild diarrhea
  • mild headache
  • mild vomiting
  • stomach discomfort or upset
  • sweating

Incidence not known

  • Decrease in passing urine (dribbling)
  • decrease in the frequency of urination
  • decrease in urine volume
  • difficulty with speaking

For Healthcare Professionals

Applies to lansoprazole: compounding powder, intravenous powder for injection, oral delayed release capsule, oral granule for reconstitution, oral suspension, oral tablet disintegrating


The most commonly reported side effects include headache, dizziness, fatigue, and malaise.


Pseudomembranous colitis may occur with triple therapy for the eradication of H. pylori.

The majority of patients with severe/protracted cases of diarrhea who discontinued treatment had symptom resolution.

Common (1% to 10%): Abdominal pain, benign fundic gland polyps, constipation, diarrhea, dry mouth, flatulence, nausea, stomachache, vomiting

Rare (0.01% to 0.1%): Candidiasis of the esophagus, glossitis, macroscopic/microscopic colitis, pancreatitis

Very rare (less than 0.01%): Colitis, stomatitis

Frequency not reported: Abdomen enlarged, abnormal stools, bezoar, cardiospasm, collagenous colitis, duodenitis, dyspepsia, dysphagia, enteritis, epigastric discomfort, eructation, esophageal disorder, esophageal stenosis, esophageal ulcer, esophagitis, fecal discoloration, gastric nodules/fundic gland polyps, gastritis, gastroenteritis, gastrointestinal anomaly/disorder/hemorrhage, gastrointestinal moniliasis, gum hemorrhage, halitosis, hematemesis, hiatal hernia, impaired gastric emptying, increased salivation, melena, mouth ulceration, positive fecal occult blood, protracted diarrhea, pseudomembranous colitis/Clostridium difficile-associated diarrhea, rectal disorder, rectal hemorrhage, sore mouth, tenesmus, tongue disorder, ulcerative colitis, ulcerative stomatitis


Skin rashes, urticaria, and pruritus generally resolved upon discontinuation of therapy.

Common (1% to 10%): Itching, pruritus, rash, urticaria

Rare (0.01% to 0.1%): Bullous rashes, cutaneous lupus erythematosus, erythema multiforme, erythematous rashes, hair loss, hair thinning, hyperhidrosis, petechia, photosensitivity, purpura, serious dermatological reactions, Stevens-Johnson syndrome, toxic epidermal necrolysis

Frequency not reported: Acne, alopecia, contact dermatitis, dry skin, fixed eruption, hair disorder, maculopapular rash, nail disorder, subacute cutaneous lupus erythematosus, skin disorder, sweating

Postmarketing reports: Fatal toxic epidermal necrolysis

Nervous system

Common (1% to 10%): Dizziness, headache, taste perversion

Rare (0.01% to 0.1%): Paresthesia, somnolence, taste disturbance, tremor, vertigo

Frequency not reported: Amnesia, cerebrovascular accident/cerebral infarction, convulsion, dementia, hemiplegia, hyperkinesia, hypertonia, hypesthesia, migraine, parosmia, syncope, taste loss

Postmarketing reports: Speech disorder


Common (1% to 10%): Increased liver enzyme levels (alkaline phosphatase, ALT, AST, GGT)

Rare (0.01% to 0.1%): Hepatitis, jaundice

Frequency not reported: Bilirubinemia, cholelithiasis, increased alkaline phosphatase, increased ALT, increased AST, increased GGT

Postmarketing reports: Hepatotoxicity


Common (1% to 10%): Fatigue

Rare (0.01% to 0.1%): Fever

Frequency not reported: Additional isolated laboratory abnormalities, asthenia, chills, deafness, ear disorder, malaise, otitis media, pain, tinnitus


A definitive relationship between use of this drug and interstitial pneumonia has not been established.

Common (1% to 10%): Dry throat

Frequency not reported: Asthma, bronchitis, cough increased, dyspnea, epistaxis, hemoptysis, hiccup, hoarseness, interstitial pneumonia, lung fibrosis, pharyngitis, pleural disorder, pneumonia, respiratory disorder, rhinitis, sinusitis, sore throat, stridor, upper respiratory tract infection, upper respiratory tract inflammation, wheezing


Uncommon (0.1% to 1%): Arthralgia, fracture of the hip/wrist/spine, myalgia

Frequency not reported: Arthritis, back pain, bone disorder, bone fracture, joint disorder, leg cramps, myasthenia, musculoskeletal pain, neck pain, neck rigidity, synovitis, systemic lupus erythematosus

Postmarketing reports: Myositis


Uncommon (0.1% to 1%): Eosinophilia, leukopenia, thrombocytopenia

Rare (0.01% to 0.1%): Agranulocytosis, anemia, hematological effects, neutropenia, pancytopenia

Frequency not reported: Abnormal albumin globulin (AG) ratio, abnormal platelets, abnormal RBC, abnormal WBC, bruising, contusion, decreased platelets, decreased WBC, hemoglobin decreased, hemolysis, increased globulins, increased platelets, increased WBC, lymphadenopathy

Postmarketing reports: Aplastic anemia, hemolytic anemia, thrombotic thrombocytopenic purpura


Rare (0.01% to 0.1%): Confusion, hallucination, insomnia, restlessness

Frequency not reported: Abnormal dreams, abnormal thinking, agitation, anxiety, apathy, depersonalization, emotional lability, hostility aggravated, libido increased/decreased, nervousness, neurosis, sleep disorder, visual hallucinations


Uncommon (0.1% to 1%): Edema

Frequency not reported: Angina, arrhythmia, bradycardia, chest pain (not otherwise specified [NOS]), hypertension, hypotension, myocardial infarction, palpitations, peripheral edema, shock/circulatory failure, tachycardia, vasodilation


Rare (0.01% to 0.1%): Anorexia, hypomagnesemia

Very rare (less than 0.01%): Hyponatremia, increased cholesterol/triglyceride levels

Frequency not reported: Avitaminosis, blood potassium increased, cyanocobalamin (vitamin B12) deficiency), decreased cholesterol, dehydration, diabetes mellitus, gout, hunger, hyperglycemia, hyperlipemia, hypoglycemia, increased appetite, increased lactate dehydrogenase (LDH), increased/decreased electrolytes, thirst, weight gain/loss

A definitive relationship between use of this drug and hyponatremia has not been established.


Rare (0.01% to 0.1%): Erectile dysfunction, impotence

Frequency not reported: Abnormal menses, albuminuria, breast enlargement, breast pain, breast tenderness, crystal urine present, dysmenorrhea, dysuria, hematuria, leukorrhea, menorrhagia, menstrual disorder, pelvic pain, penis disorder, polyuria, testis disorder, urethral pain, urinary frequency, urinary retention, urinary tract infection, urinary urgency, urination impaired, vaginitis


Rare (0.01% to 0.1%): Angioedema

Very rare (less than 0.01%): Anaphylactic reaction, anaphylactic shock

Frequency not reported: Allergic reaction

Postmarketing reports: Anaphylactoid reactions


Rare (0.01% to 0.1%): Visual disturbances

Frequency not reported: Abnormal vision, amblyopia, blepharitis, blurred vision, cataract, conjunctivitis, diplopia, dry eyes, eye disorder, eye pain, glaucoma, photophobia, ptosis, retinal degeneration/disorder, visual field defect


Some cases of interstitial nephritis resulted in renal failure.

Rare (0.01% to 0.1%): Interstitial nephritis

Frequency not reported: Acute interstitial nephritis, blood urea increased, kidney calculus, kidney pain, glycosuria, increased creatinine, renal dysfunction, renal failure


Rare (0.01% to 0.1%): Gynecomastia

Frequency not reported: Goiter, hypothyroidism, increased gastrin levels, increased glucocorticoids


Frequency not reported: Carcinoma, laryngeal neoplasia, metaplasia, skin carcinoma


Frequency not reported: Candidiasis, flu syndrome, infection NOS

Editorial References and Review

Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/3/2022.

Source: Drugs.com Prevacid (www.drugs.com/prevacid.html).