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Oxybutynin reduces muscle spasms of the bladder and urinary tract.
Oxybutynin is used to treat symptoms of overactive bladder, such as frequent or urgent urination, incontinence (urine leakage), and increased night-time urination.
Oxybutynin may also be used for purposes not listed in this medication guide.
You should not use oxybutynin if you have untreated or uncontrolled narrow-angle glaucoma, a blockage in your digestive tract (stomach or intestines), or if you are unable to urinate.
Before using oxybutynin, tell your doctor if you have glaucoma, liver or kidney disease, an enlarged prostate, myasthenia gravis, ulcerative colitis, a blockage in your stomach or intestines, or a stomach disorder such as gastroesophageal reflux disease (GERD) or slow digestion.
Avoid becoming overheated or dehydrated during exercise and in hot weather. Oxybutynin can decrease perspiration and you may be more prone to heat stroke.
This medication may cause blurred vision and may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly.
There are many other medicines that can interact with oxybutynin. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you.
Stop using this medication and call your doctor if you have serious side effects such as hot and dry skin, extreme thirst, severe stomach pain or constipation, pain or burning when you urinate, or if you stop urinating.
You should not use this medication if you are allergic to oxybutynin, or if you have:
untreated or uncontrolled narrow-angle glaucoma;
a blockage in your digestive tract (stomach or intestines); or
if you are unable to urinate.
To make sure oxybutynin is safe for you, tell your doctor if you have:
glaucoma;
liver disease;
kidney disease;
an enlarged prostate;
ulcerative colitis;
Parkinson's disease;
a nerve disorder that affects your heart rate, blood pressure, or digestion;
a muscle disorder such as myasthenia gravis; or
a stomach disorder such as gastroesophageal reflux disease (GERD) or slow digestion.
Tell your doctor if you are pregnant or breastfeeding.
Take oxybutynin exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.
Take this medicine with a full glass of water, at the same time each day.
Oxybutynin may be taken with or without food.
Swallow the extended-release tablet whole and do not crush, chew, or break it.
Measure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).
Some tablets are made with a shell that is not absorbed or melted in the body. Part of this shell may appear in your stool. This is normal and will not make the medicine less effective.
Store at room temperature away from moisture and heat.
Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Avoid driving or hazardous activity until you know how oxybutynin will affect you. Your reactions could be impaired.
Avoid becoming overheated or dehydrated during exercise and in hot weather. Oxybutynin can decrease sweating and you may be more prone to heat stroke.
Drinking alcohol with this medicine can increase side effects.
Get emergency medical help if you have signs of an allergic reaction to oxybutynin: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop using this medicine and call your doctor at once if you have:
severe stomach pain or constipation;
blurred vision, tunnel vision, eye pain, or seeing halos around lights;
little or no urination;
painful or difficult urination; o
dehydration symptoms--feeling very thirsty or hot, being unable to urinate, heavy sweating, or hot and dry skin;
Side effects such as dry mouth, constipation, and confusion may be more likely in older adults.
Common oxybutynin side effects may include:
dizziness, drowsiness;
blurred vision;
dry mouth; or
diarrhea, constipation.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Using oxybutynin with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.
Tell your doctor about all your other medicines, especially:
medicine to treat depression, anxiety, mood disorders, or mental illness;
cold or allergy medicine (Benadryl and others);
medicine to treat Parkinson's disease;
medicine to treat stomach problems, motion sickness, or irritable bowel syndrome;
medicine to treat overactive bladder; or
bronchodilator asthma medication.
This list is not complete. Other drugs may interact with oxybutynin, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use oxybutynin only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.
Source: Drugs.com Oxybutynin Chloride Er (www.drugs.com/oxybutynin.html).
Commonly reported side effects of oxybutynin include: constipation, drowsiness, and local pruritus. Other side effects include: urinary tract infection, blurred vision, dizziness, dyspepsia, headache, nausea, rhinitis, and xerophthalmia. See below for a comprehensive list of adverse effects.
Applies to oxybutynin: oral syrup, oral tablet, oral tablet extended release
Other dosage forms:
Along with its needed effects, oxybutynin may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking oxybutynin:
Rare
Get emergency help immediately if any of the following symptoms of overdose occur while taking oxybutynin:
Symptoms of overdose
Some side effects of oxybutynin may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
Less common or rare
Incidence not known
- Observed during clinical practice with oxybutynin; estimates of frequency cannot be determined
Applies to oxybutynin: oral syrup, oral tablet, oral tablet extended release, transdermal film extended release, transdermal gel
Uncommon (0.1% to 1%): Hypersensitivity
Frequency not reported: Anaphylactic reaction
Common (1% to 10%): Palpitations
Uncommon (0.1% to 1%): Cardiac arrhythmia tachycardia, vasodilation, hypertension, flushing
Frequency not reported: Heat stroke
Very common (10% or more): Dry skin, pruritus
Common (1% to 10%): Flushing, rash
Frequency not reported: Angioedema, hypohidrosis
Postmarketing reports: Decreased lactation
Very common (10% or more): Dry mouth (up to 72%), constipation (up to 15%), nausea
Common (1% to 10%): Diarrhea, dyspepsia, abdominal pain, vomiting, flatulence, gastroesophageal reflux disease
Uncommon (0.1% to 1%): Abdominal discomfort
Frequency not reported: Pseudo-obstruction in patients at risk (elderly or patients with constipation and treated with other drugs that decrease intestinal motility), decreased GI motility
The most common (incidence 5% or greater) adverse reactions were dry mouth, constipation, diarrhea, headache, somnolence, and dizziness.
Common (1% to 10%): Urinary tract infection, urinary hesitation, urinary retention, dysuria, increased post void retention
Frequency not reported: Impotence, suppression of lactation, cystitis, aggravation of prostatic hypertrophy
Uncommon (0.1% to 1%): Fungal infection
Very common (10% or more): Application site pruritus (16.8%)
Common (1% to 10%): Application site erythema, application site vesicles, application site rash, application site macules
Uncommon (0.1% to 1%): Anorexia, fluid retention
Uncommon (0.1% to 1%): Back pain
Very common (10% or more): Dizziness (up to 17%), somnolence (up to 14%), headache, drowsiness, confusion
Common (1% to 10%): Dysgeusia
Uncommon (0.1% to 1%): Dysphagia, convulsions
Frequency not reported: Cognitive disorders in elderly, convulsions, agitation, nightmares, anxiety, paranoia, symptoms of depression, hallucinations, asthenia, insomnia, restlessness, dependence to this drug (in patients with history of drug or substance abuse)
Common (1% to 10%): Blurred vision, dry eye, abnormal vision
Uncommon (0.1% to 1%): Angle closure glaucoma
Frequency not reported: Onset of narrow-angle glaucoma, mydriasis, intraocular hypertension, amblyopia, cycloplegia, decreased lacrimation
Common (1% to 10%): Fatigue
Uncommon (0.1% to 1%): Dysphonia, thirst
Frequency not reported: Falls, accidental injury
Common (1% to 10%): Insomnia, nervousness
Uncommon (0.1% to 1%): Hallucinations, confusional state, agitation, memory impairment
Frequency not reported: Psychotic disorder, anxiety, nightmares, paranoia
Common (1% to 10%): Cough, oropharyngeal pain, dry throat, nasal dryness
Uncommon (0.1% to 1%): Upper respiratory tract infection, rhinitis, chest discomfort, hoarseness
Rare (0.01% to 0.1%): Nasal congestion, throat irritation
Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.
Source: Drugs.com Oxybutynin Chloride Er (www.drugs.com/oxybutynin.html).
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