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Np thyroid 90

Generic Name: levothyroxine, liothyronine
Dosage Form: tablet
NP Thyroid 90 official prescribing information for healthcare professionals. Includes: indications, dosage, adverse reactions, pharmacology and more.

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Drug Information:
NP Thyroid (Thyroid tablets, USP) for oral use is a natural preparation derived from porcine Thyroid glands. They contain both tetraiodothyronine sodium (T4 levothyroxine) and triiodothyronine sodium (T3 liothyronine) providing 38 mcg levothyroxine (T4) and 9 mcg liothyronine (T3) per grain of Thyroid. The iNactive ingredients are Calcium stearate, dextrose monohydrate, maltodextrin and Mineral Oil. CLINICAL PHARMACOLOGY: The steps in the synthesis of the Thyroid hormones are controlled by thyrotropin (Thyroid Stimulating Hormone, TSH) secreted by the anterior pituitary. This hormone’s secretion is in turn controlled by a feedback mechanism effected by the Thyroid hormones themselves and by thyrotropin releasing hormone (TRH), a tripeptide of hypothalamic origin. Endogenous Thyroid hormone secretion is suppressed when exogenous Thyroid hormones are administered to euThyroid individuals in excess of the normal gland’s secretion. The mechanisms by which Thyroid hormones exert their physiologic action are not well understood. These hormones enhance oxygen consumption by most tissues of the body, increase the basal metabolic rate, and the metabolism of carbohydrates, lipids, and proteins. Thus, they exert a profound influence on every organ system in the body and are of particular importance in the development of the central nervous system. The normal Thyroid gland contains approximately 200 mcg of levothyroxine (T4) per gram of gland, and 15 mcg of liodothyronine (T3) per gram. The ratio of these two hormones in the circulation does not represent the ratio in the Thyroid gland, since about 80 percent of peripheral triiodothyronine comes from monodeiodination of levothyroxine. Peripheral monodeiodination of levothyroxine at the 5 position (inner ring) also results in the formation of reverse triiodothyronine (T3), which is calorigenically iNactive. Triiodothyronine (T3) levels are low in the fetus and newborn, in old age, in chronic caloric deprivation, hepatic cirrhosis, renal failure, surgical stress, and chronic illnesses representing what has been called the “T3 thyronine syndrome.” Learn more
Inactive Ingredients Ingredient Name Strength CALCIUM STEARATE   DEXTROSE MONOHYDRATE   MALTODEXTRIN   MINERAL OIL  
Product Characteristics Color brown (BROWN) Score no score Shape ROUND Size 8mm Flavor Imprint Code AP;331 Contains     
Packaging # Item Code Package Description 1 NDC:42192-331-01 100 TABLET in 1 BOTTLE
Marketing Information Marketing Category Application Number or Monograph Citation Marketing Start Date Marketing End Date unapproved drug other 02/03/2011
Labeler - Acella Pharmaceuticals, LLC (825380939) Registrant - Acella Pharmaceuticals, LLC (825380939)  

More about NP Thyroid (thyroid desiccated)

Consumer resources

Professional resources

Other brands: Armour Thyroid

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Editorial References and Review

Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.

Source: Drugs.com Np Thyroid 90 (www.drugs.com/pro/np-thyroid-90.html).

Np thyroid 90 Side Effects

NP Thyroid Side Effects

Note: This document contains side effect information about thyroid desiccated. Some of the dosage forms listed on this page may not apply to the brand name NP Thyroid.

For the Consumer

Applies to thyroid desiccated: oral tablet

Warning

Oral route (Tablet)

In euthyroid patients, doses within the range of daily hormonal requirements are ineffective for weight reduction. Larger doses may produce serious or even life-threatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects.

Along with its needed effects, thyroid desiccated (the active ingredient contained in NP Thyroid) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Get emergency help immediately if any of the following symptoms of overdose occur while taking thyroid desiccated:

For Healthcare Professionals

Applies to thyroid desiccated: compounding powder, oral capsule, oral tablet

General

Adverse reactions other than those attributable to hyperthyroidism due to therapeutic overdose are rare. Excessive doses may result in a hypermetabolic state resembling in every respect the condition of endogenous origin.

If signs and symptoms of overdosage appear, the dosage should be reduced or therapy temporarily discontinued and may be reinstituted at a lower dosage. Normal hypothalamic-pituitary-thyroid axis function has been restored in 6 to 8 weeks after thyroid suppression.

Editorial References and Review

Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.

Source: Drugs.com Np Thyroid 90 (www.drugs.com/pro/np-thyroid-90.html).

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