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Northera

Generic Name: droxidopa (DROX i DOP a)
Brand Names: Northera
Northera (droxidopa) is used to treat neurogenic orthostatic hypotension. Includes Northera side effects, interactions and indications.
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Drug Information:
NorThera (droxidopa) works by constricting (narrowing) the blood vessels and increasing blood pressure. NorThera is used to treat low blood pressure that causes severe dizziness or a light-headed feeling, like you might pass out. NorThera is for use in people with conditions of the nervous system that can cause low blood pressure (such as Parkinson's disease, multiple system atrophy, autonomic failure, and others). NorThera can increase your blood pressure even while you are lying down. You may need to keep your head elevated during sleep to help prevent high blood pressure. Follow your doctor's instructions about how to position your body while you are lying down or sleeping. Learn more

Northera Side Effects

Northera Side Effects

Note: This document contains side effect information about droxidopa. Some of the dosage forms listed on this page may not apply to the brand name Northera.

In Summary

More frequent side effects include: hypertension. See below for a comprehensive list of adverse effects.

For the Consumer

Applies to droxidopa: oral capsule

Warning

Oral route (Capsule)

Monitor supine blood pressure before and during treatment, and more frequently when increasing doses. Elevating the head of the bed lessens the risk of supine hypertension and blood pressure should be measured in this position. If supine hypertension cannot be managed by elevating the head of the bed, reduce or discontinue droxidopa.

Along with its needed effects, droxidopa (the active ingredient contained in Northera) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking droxidopa:

More common

  • Bladder pain
  • bloody or cloudy urine
  • blurred vision
  • difficult, burning, or painful urination
  • dizziness
  • fainting
  • frequent urge to urinate
  • lower back or side pain
  • nervousness
  • pounding in the ears
  • slow or fast heartbeat

Some side effects of droxidopa may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Headache
  • nausea

For Healthcare Professionals

Applies to droxidopa: oral capsule

Cardiovascular

Common (1% to 10%): Hypertension (greater than 5%)

Frequency not reported: Supine hypertension, exacerbation of existing heart disease, arrhythmias, and congestive heart failure

Gastrointestinal

Common (1% to 10%): Nausea

Genitourinary

Very common (10% or more): Urinary tract infections (15% in the elderly)

Musculoskeletal

Very common (10% or more): Falls (24% in the elderly)

Nervous system

Very common (10% or more): Headache (up to 15%), syncope (13% in the elderly), dizziness (up to 11%)

Editorial References and Review

Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.

Source: Drugs.com Northera (www.drugs.com/northera.html).