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Nimodipine

Generic Name: nimodipine (nih MO dih peen)
Brand Name: Nymalize, Nimotop
Physician reviewed nimodipine patient information - includes nimodipine description, dosage and directions.
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Drug Information:
Nimodipine is a Calcium channel blocker that is used to prevent brain damage caused by reduced blood flow to the brain resulting from aneurysm (a dilated or ruptured blood vessel in the brain). Nimodipine may also be used for purposes not listed in this medication guide. Tell your doctor about all your current medicines and any you start or stop using. Many drugs can interact, and some drugs should not be used together. The liquid from a nimodipine capsule should never be injected through a needle into the body, or death may occur. Learn more

Nimodipine Side Effects

Nimodipine Side Effects

In Summary

More frequently reported side effects include: hypotension. See below for a comprehensive list of adverse effects.

For the Consumer

Applies to nimodipine: oral capsule liquid filled, oral solution

Warning

Oral route (Capsule, Liquid Filled)

Do not administer nimodipine intravenously or by other parenteral routes. Deaths and serious, life threatening adverse events have occurred when the contents of nimodipine capsules have been injected parenterally.

Along with its needed effects, nimodipine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking nimodipine:

Less common

  • Blurred vision
  • chest pain or discomfort
  • confusion
  • difficult or labored breathing
  • fast, pounding, or irregular heartbeat or pulse
  • lightheadedness, dizziness, or fainting
  • shortness of breath
  • slow or irregular heartbeat
  • sweating
  • swelling
  • tightness in the chest
  • unusual tiredness or weakness

Some side effects of nimodipine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

  • Abdominal or stomach cramps, discomfort, or pain
  • back pain
  • blemishes on the skin
  • constipation
  • diarrhea
  • discouragement
  • feeling sad or empty
  • headache
  • indigestion
  • irritability
  • lack or loss of appetite
  • loss of interest or pleasure
  • muscle pain
  • nausea or vomiting
  • pimples
  • rash
  • swollen mouth and tongue
  • tiredness
  • trouble concentrating
  • trouble sleeping
  • unpleasant taste
  • urge to have bowel movement

For Healthcare Professionals

Applies to nimodipine: oral capsule, oral liquid

General

The most commonly reported side effects included decreased blood pressure, diarrhea, and rash.

Cardiovascular

Very common (10% or more): Decreased blood pressure (up to 50%)

Common (1% to 10%): Bradycardia, edema, EKG abnormalities, flushing, tachycardia

Uncommon (0.1% to 1%): Hypotension, vasodilation

Frequency not reported: Congestive heart failure, deep vein thrombosis, hematoma, hypertension, palpitations, rebound vasospasm

Gastrointestinal

Common (1% to 10%): Diarrhea, gastrointestinal symptoms, nausea

Rare (0.01% to 0.1%): Ileus

Frequency not reported: Gastrointestinal hemorrhage, vomiting

Dermatologic

Common (1% to 10%): Acne, rash

Frequency not reported: Diaphoresis, itching

Musculoskeletal

Common (1% to 10%): Cramp, muscle pain

Hepatic

Common (1% to 10%): Abnormal liver function test

Uncommon (0.1% to 1%): Elevated alkaline phosphatase levels, elevated ALT levels

Rare (0.01% to 0.1%): Transient increase in liver enzymes

Frequency not reported: Hepatitis, jaundice

Nervous system

Common (1% to 10%): Headache

Frequency not reported: Alterations in consciousness, dizziness, lightheadedness, neurological deterioration

Respiratory

Common (1% to 10%): Dyspnea

Frequency not reported: Wheezing

Psychiatric

Common (1% to 10%): Depression

Hematologic

Uncommon (0.1% to 1%): Decreased platelet counts, thrombocytopenia

Frequency not reported: Anemia, disseminated intravascular coagulation

Hypersensitivity

Uncommon (0.1% to 1%): Allergic reaction

Local

Rare (0.01% to 0.1%): Injection site reaction, infusion site phlebitis, infusion site reaction, infusion site thrombophlebitis

Other

Frequency not reported: Phenytoin toxicity

Metabolic

Uncommon (0.1% to 1%): Elevated lactate dehydrogenase levels, fluid retention, non-fasting elevated serum glucose levels

Frequency not reported: Hyponatremia

Editorial References and Review

Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.

Source: Drugs.com Nimodipine (www.drugs.com/mtm/nimodipine.html).