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Niacinamide Prescription
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Generic Name: Niacinamide (nye a SIN a mide)
Easy-to-read patient leaflet for Niacinamide. Includes indications, proper use, special instructions, precautions, and possible side effects.
Generic Name: Niacinamide (nye a SIN a mide)
Easy-to-read patient leaflet for Niacinamide. Includes indications, proper use, special instructions, precautions, and possible side effects.
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1 tablets of Niacinamide 40 mg
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Niacinamide Drug Information:

This medicine may interact with other drugs or health problems. Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Niacinamide with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor. Use Niacinamide as ordered by your doctor. Read all information given to you. Follow all instructions closely. Learn more

Niacinamide Side Effects

For the Consumer

Applies to niacinamide: oral tablet, oral tablet extended release

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Signs of high blood sugar like confusion, feeling sleepy, more thirst, more hungry, passing urine more often, flushing, fast breathing, or breath that smells like fruit.
  • Signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
  • Muscle pain or weakness.
  • Chest pain or pressure.
  • Dizziness or passing out.
  • Shortness of breath.
  • Sweating a lot.
What are some other side effects of this drug?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

  • Flushing. Taking aspirin 30 minutes before taking this drug may help. If you wake up at night with flushing, get up slowly if you feel like passing out or you are dizzy.
  • Itching.
  • Diarrhea.
  • Upset stomach or throwing up.
  • Cough.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

For Healthcare Professionals

Applies to niacinamide: compounding powder, oral tablet


Cardiovascular side effects are rare and mild and have included tachycardia.


Metabolic side effects have included hyperglycemia and hyperuricemia.

Nervous system

Nervous system side effects have included headache.


Gastrointestinal side effects have included bloating, flatulence, diarrhea, stomach upset, and nausea.


Dermatologic side effects have included increased sebaceous gland activity, dry skin, itching, and rash.

Editorial References and Review

Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/3/2022.

Source: Drugs.com Niacinamide (www.drugs.com/cdi/niacinamide.html).