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Commonly reported side effects of niacin include: pruritus, nausea, and flushing. Other side effects include: skin rash, and vomiting. See below for a comprehensive list of adverse effects.
For the ConsumerApplies to niacin: oral capsule, oral capsule extended release, oral tablet, oral tablet extended release
Along with its needed effects, niacin may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking niacin:
Less common
Some side effects of niacin may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Less common
Incidence not known
For Healthcare Professionals
Applies to niacin: compounding powder, oral capsule, oral capsule extended release, oral liquid, oral tablet, oral tablet extended release
CardiovascularVery common (10% or more): Flushing (i.e., warmth, redness, itching, and/or tingling) (up to 88%)
Frequency not reported: Tachycardia, palpitations, atrial fibrillation, other cardiac arrhythmias, syncope, hypotension, postural hypotension
DermatologicCommon (1% to 10%): Rash, pruritus
Frequency not reported: Sweating, skin burning sensation, maculopapular rash, dry skin
Postmarketing reports: Skin discoloration
GastrointestinalVery common (10% or more): Diarrhea (up to 14%), nausea (up to 11%)
Common (1% to 10%): Vomiting
Frequency not reported: Peptic ulcers, eructation, flatulence
HematologicPostmarketing reports: Slight reductions in platelet counts, prothrombin time prolonged
HypersensitivityPostmarketing reports: Hypersensitivity reactions (e.g., anaphylaxis, angioedema, urticaria, flushing, dyspnea, tongue edema, larynx edema, face edema, peripheral edema, laryngismus, vesiculobullous rash)
HepaticPostmarketing reports: Hepatitis, jaundice
MetabolicFrequency not reported: Decreased glucose tolerance, gout
MusculoskeletalFrequency not reported: Myalgia, myopathy
Nervous systemFrequency not reported: Dizziness, syncope
Postmarketing reports: Migraine, asthenia, paresthesia
OcularPostmarketing reports: Blurred vision, macular edema
PsychiatricPostmarketing reports: Insomnia, nervousness
OtherFrequency not reported: Chills, edema
RespiratoryCommon (1% to 10%): Cough increased
Frequency not reported: Dyspnea
Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/3/2022.
Source: Drugs.com Niacin (www.drugs.com/niacin.html).
July 15, 2021
July 15, 2021
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