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Nembutal sodium

Generic Name: pentobarbital (injection) (PEN toe BAR bi tal)
Brand Name: Nembutal Sodium
Physician reviewed Nembutal Sodium (injection) (injection) patient information - includes Nembutal Sodium (injection) description, dosage and directions.
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Drug Information:
Nembutal Sodium is a barbiturate (bar-BIT-chur-ate). This medicine slows the activity of your brain and nervous system. Nembutal Sodium is used short-term as a sedative to treat insomnia, or to cause you to fall asleep for surgery. This medicine is also used as an emergency treatment for seizures. Nembutal Sodium may also be used for purposes not listed in this medication guide. You should not use Nembutal Sodium if you have a history of porphyria (a genetic enzyme disorder that causes symptoms affecting the skin or nervous system). Learn more

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Nembutal sodium Side Effects

Note: This document contains side effect information about pentobarbital. Some of the dosage forms listed on this page may not apply to the brand name Nembutal Sodium.

For the Consumer

Applies to pentobarbital: parenteral solution for injection

Side effects include:

Residual sedation, drowsiness, lethargy, vertigo, nausea, vomiting, headache.

For Healthcare Professionals

Applies to pentobarbital: compounding powder, injectable solution, oral capsule, oral elixir, rectal suppository

Nervous system

Common (1% to 10%): Somnolence

Uncommon (0.1% to 1%): Ataxia, central nervous system (CNS) depression, dizziness, hyperkinesia, syncope

Frequency not reported: Headache


Uncommon (0.1% to 1%): Abnormal thinking, agitation, anxiety, confusion, dizziness, hallucination, nervousness, nightmares, psychiatric disturbance


Uncommon (0.1% to 1%): Constipation, nausea, vomiting


Uncommon (0.1% to 1%): Apnea, hypoventilation


Uncommon (0.1% to 1%): Bradycardia, hypotension


Frequency not reported: Angioedema, hypersensitivity reactions


Frequency not reported: Exfoliative dermatitis, skin rashes


Frequency not reported: Megaloblastic anemia

Megaloblastic anemia occurred with chronic phenobarbital use.


Frequency not reported: Liver damage


Frequency not reported: Fever


Frequency not reported: Injection site reactions

Editorial References and Review

Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.

Source: Drugs.com Nembutal Sodium (www.drugs.com/mtm/nembutal-sodium-injection.html).