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Mitomycin Prescription
Generic Name: mitomycin ophthalmic (MYE toe MYE sin off THAL mik)
Brand Name: Mitosol
Physician reviewed mitomycin ophthalmic patient information - includes mitomycin ophthalmic description, dosage and directions.
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Mitomycin Drug Information:

Mitomycin is an antimetabolite medicine that interferes with the growth and spread of certain cells in the body. Mitomycin ophthalmic (for the eyes) is used during glaucoma surgery. Mitomycin ophthalmic may also be used for purposes not listed in this medication guide. You should not be treated with mitomycin ophthalmic if you are pregnant. You should not be treated with this medicine if you are allergic to mitomycin. You should not be treated with mitomycin ophthalmic if you are pregnant, or if you think you may be pregnant. Mitomycin could harm the unborn baby or cause birth defects. Learn more

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Mitomycin Side Effects

For the Consumer

Applies to mitomycin ophthalmic: topical application pad, topical application powder for solution

Along with its needed effects, mitomycin ophthalmic may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking mitomycin ophthalmic:

More common

  • Blindness
  • blurred vision or other change in vision
  • decreased vision
  • dislocated eye implants
  • eye pain
  • eye redness
  • flashes of light or floaters in vision
  • headache
  • irritation or inflammation of the eye
  • seeing flashes or sparks of light
  • seeing floating spots before the eyes, or a veil or curtain appearing across part of vision
  • tearing of the eyes

Some side effects of mitomycin ophthalmic may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Opening of the surgical wound
  • raising of the upper eyelid
  • sensitivity of the eyes to light
  • throbbing pain

For Healthcare Professionals

Applies to mitomycin ophthalmic: ophthalmic kit


The most commonly reported side effects include blebitis, corneal changes, and other localized reactions.


Frequency not reported: Blebitis, bleb ulceration, chronic bleb leak, encapsulated/cystic bleb, bleb-related infection, conjunctival necrosis, thin-walled bleb, Descemet's detachment, induced astigmatism, corneal epithelial damage, superficial punctate keratitis, endophthalmitis, hypotony, choroidal reaction, choroidal detachment, choroidal reactions, choroidal detachment, choroidal effusion, serious choroidal detachment, suprachoroidal hemorrhage, hypotony maculopathy, presence of supraciliochoroidal effusion, iritis, cataract development, capsular constriction, posterior synechiae, retinal pigment epithelial tear, serous/rhegatogenous retinal detachment, hyphema, vitreal/retinal/subconjunctival/disk hemorrhage, macular edema, sclera thinning/ulceration, intraocular lens capture, disk swelling, malignant glaucoma, lacrimal drainage system obstruction, ciliary block, corneal vascularization, decreased visual acuity, cystic conjunctival degeneration, upper eyelid retraction, dislocated implants, severe loss of vision, hemiretinal/central retinal vein occlusion


Frequency not reported: Wound dehiscence/scleral wound dehiscence


Frequency not reported: Blood clot

Editorial References and Review

Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.

Source: Drugs.com Mitomycin (www.drugs.com/mtm/mitomycin-ophthalmic.html).