Please wait...

Mesna Prescription
Generic Name: mesna (oral/injection) (MEZ nah)
Brand Name: Mesnex
Physician reviewed mesna (oral/injection) (oral/injection) patient information - includes mesna (oral/injection) description, dosage and directions.
  • Prescription Settings
  • X
  • medly Free, same-day prescription delivery to your doorstep is available in your area.
  • Learn more
  • Local Pharmacy Pickup available at . Pick up your medication at any of our participating pharmacies.
  • Mail Order Home Delivery available at , the easiest way to receive your medications.

Mesna Coupons & Prices

Set your location
for drug prices near you

Enter your zip code

Please wait while the prices are loaded...
Click here to try again.

Don’t see your pharmacy listed? Most pharmacies accept our discounts, so have your pharmacist enter this coupon to see if you will save money:

Mesna Drug Information:

Mesna is used to prevent bleeding in the bladder (hemorrhagic cystitis) during chemotherapy with Ifosfamide (Ifex). Mesna will not prevent other side effects caused by Ifosfamide. Mesna may also be used for purposes not listed in this medication guide. Get emergency medical help if you have signs of a serious reaction: fever, nausea, vomiting, racing heartbeats, hives, rash or redness, skin pain or swelling, blisters or peeling, joint or muscle pain, feeling light-headed, trouble breathing, mouth sores, or swelling in your face or throat. Learn more

Buy Mesna Online and Mesna Delivery

USARx offers the following ways to purchase this medication. Choose the Best option for you!

  • Guaranteed Price

    Local Pharmacy Pickup of Mesna

    Pay this amount and pick up your prescription at ANY Retail pharmacy of your choice! Walgreens, CVS, Walmart, etc.

  • 30-day supply
    90-day supply

    Mail Order Home Delivery of Mesna

    The easiest way to receive your medications.

Mesna Side Effects

For the Consumer

Applies to mesna: oral tablet

Other dosage forms:

  • intravenous solution

Along with its needed effects, mesna may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking mesna:

More common

  • Black, tarry stools
  • bleeding gums
  • bloating or swelling of the face, arms, hands, lower legs, or feet
  • blood in the urine
  • chest pain
  • chills
  • convulsions
  • cough
  • decreased urination
  • dizziness
  • dry mouth
  • fainting
  • fast, pounding, or irregular heartbeat or pulse
  • fever
  • increased thirst
  • irregular heartbeat
  • lightheadedness
  • loss of appetite
  • mood changes
  • muscle pain or cramps
  • nausea or vomiting
  • numbness or tingling in the hands, feet, or lips
  • painful or difficult urination
  • pinpoint red spots on the skin
  • rapid breathing
  • rapid weight gain
  • sore throat
  • sores, ulcers, or white spots on the lips or in the mouth
  • sunken eyes
  • swelling
  • swollen glands
  • tightness in the chest
  • trouble breathing
  • unusual bleeding or bruising
  • unusual tiredness or weakness
  • unusual weight gain or loss
  • wrinkled skin

Less common

  • Blurred vision
  • confusion
  • dizziness dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • rapid breathing
  • sweating

Incidence not known

  • Coughing or spitting up blood
  • dark urine
  • general tiredness and weakness
  • headache
  • light-colored stools
  • nervousness
  • pounding in the ears
  • slow or fast heartbeat
  • upper right abdominal or stomach pain
  • yellow eyes and skin

Some side effects of mesna may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Abdominal or stomach pain
  • diarrhea
  • difficulty having a bowel movement (stool)
  • hair loss
  • lack or loss of strength
  • sleepiness or unusual drowsiness
  • weight loss

Less common

  • Acid or sour stomach
  • back pain
  • belching
  • feeling of warmth
  • heartburn
  • increased sweating
  • indigestion
  • redness of the face, neck, arms, and occasionally, upper chest
  • stomach discomfort or upset
  • trouble sleeping

Incidence not known

  • Change or loss of taste

For Healthcare Professionals

Applies to mesna: injectable solution, intravenous kit, oral tablet


Very common (10% or more): Nausea (65%), vomiting (35%), constipation (28%), anorexia (21%), abdominal pain/colic (14%), diarrhea

Common (1% to 10%): Dyspepsia, dehydration, anorexia, mucosal irritation, flatulence, burning pain (substernal/epigastric), gingival bleeding

Frequency not reported: Dry mouth, bad taste

Postmarketing reports: Dysgeusia


Very common (10% or more): Leukopenia (25%), thrombocytopenia (21%), anemia (20%), granulocytopenia (16%)

Common (1% to 10%): Lymphadenopathy

Frequency not reported: Activated partial thromboplastin time prolonged

Postmarketing reports: Decrease in lymphocyte count (generally reversible within one week)

Nervous system

Very common (10% or more): Lightheadedness, lethargy/drowsiness

Common (1% to 10%): Dizziness, headache, pain, somnolence, paresthesia, hyperesthesia, syncope, hypoesthesia, attention disturbance

Postmarketing reports: Convulsion


Very common (10% or more): Chest pain (10%)

Common (1% to 10%): Hypotension, tachycardia, palpitations

Postmarketing reports: Hypertension


Common (1% to 10%): Back pain, arthralgia, myalgia, pain in extremity, pain in jaw

Frequency not reported: Rigors


Very common (10% or more): Hypokalemia (10%)


Frequency not reported: Acute renal failure


Very common (10% or more): Fatigue (24%), fever (24%), asthenia (15%), flushing

Common (1% to 10%): Edema, peripheral edema, facial edema, pallor, insomnia, nightmares

Frequency not reported: Fever, malaise


Very common (10% or more): Alopecia (12%), rash

Common (1% to 10%): Hyperhidrosis, pruritus

Frequency not reported: Erythema multiforme, drug rash, ulcerations and/or bullae/blistering, angioedema, urticaria, burning sensation, erythema


Common (1% to 10%): Hematuria, dysuria


Postmarketing reports: Hepatitis


Common (1% to 10%): Pneumonia

Frequency not reported: Influenza-like symptoms


Very common (10% or more): Infusion site pruritus, infusion site rash

Common (1% to 10%: Infusion site pain, infusion site erythema, infusion site urticaria, infusion site swelling


Common (1% to 10%): Conjunctivitis, photophobia, blurred vision


Common (1% to 10%): Anxiety, confusion


Very common (10% or more): Dyspnea (11%)

Common (1% to 10%): Cough, nasal congestion, pleuritic pain, bronchospasm, laryngeal discomfort, epistaxis

Frequency not reported: Pharyngitis, rhinitis, respiratory distress, hypoxia

Postmarketing reports: Hemoptysis

Editorial References and Review

Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/27/2021.

Source: Drugs.com Mesna (www.drugs.com/mtm/mesna-oral-injection.html).