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Marinol Prescription
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Generic Name: dronabinol (droe NAH bih nol)
Brand Names: Marinol, Syndros
Marinol is a man-made form of cannabis used to treat loss of appetite in people with AIDS. Learn about side effects, interactions and indications.
Generic Name: dronabinol (droe NAH bih nol)
Brand Names: Marinol, Syndros
Marinol is a man-made form of cannabis used to treat loss of appetite in people with AIDS. Learn about side effects, interactions and indications.
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30 tablets of Marinol 40 mg
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Marinol Drug Information:

Marinol (Dronabinol) is a man-made form of cannabis (also known as marijuana). Marinol is used to treat loss of appetite that causes weight loss in people with AIDS. Marinol is also used to treat severe nausea and vomiting caused by cancer chemotherapy. It is usually given after medicines to control nausea and vomiting have been tried without success. Marinol may cause new or worsening psychosis (unusual thoughts or behavior), especially if you have ever had depression or mental illness. Marinol can raise or lower blood pressure, especially in older adults or in people with heart problems. Learn more

Marinol Side Effects

Note: This document contains side effect information about dronabinol. Some of the dosage forms listed on this page may not apply to the brand name Marinol.

For the Consumer

Applies to dronabinol: oral capsule, oral capsule liquid filled, oral solution

Along with its needed effects, dronabinol (the active ingredient contained in Marinol) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking dronabinol:

Less common

  • Changes in mood
  • confusion
  • delusions
  • fast or pounding heartbeat
  • feelings of unreality
  • loss of memory
  • mental depression
  • nervousness or anxiety
  • problems with memory
  • seeing, hearing, or feeling things that are not there


  • Blurred vision
  • chills
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • sweating
  • unusual tiredness or weakness

Incidence not known

  • Fainting
  • feeling of warmth
  • hives or rash
  • redness of the face, neck, arms, and occasionally, upper chest
  • seizures
  • sores in the mouth
  • swelling of the lips
  • tightness in the throat
  • trouble sleeping

Get emergency help immediately if any of the following symptoms of overdose occur while taking dronabinol:

Symptoms of overdose

  • Being forgetful
  • change in how fast you think time is passing
  • change in your sense of smell, taste, sight, sound, or touch
  • constipation
  • decrease in motor coordination
  • drowsiness (severe)
  • dryness of the mouth (severe)
  • false sense of well-being
  • feeling sluggish
  • panic reaction
  • problems in urinating
  • redness of the eyes
  • seizures
  • slurred speech
  • unusual drowsiness or dullness

Some side effects of dronabinol may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Clumsiness or unsteadiness
  • dizziness
  • drowsiness
  • false sense of well-being
  • nausea
  • trouble with thinking
  • vomiting

Less common or rare

  • Abdominal or stomach pain
  • flushing of the face
  • lack or loss of strength
  • restlessness


  • Burning, dry, or itching eyes
  • continuing ringing or buzzing or other unexplained noise in the ears
  • cough
  • diarrhea
  • discharge, excessive tearing
  • headache
  • hearing loss
  • redness, pain, swelling of the eye, eyelid, or inner lining of the eyelid
  • runny nose
  • sneezing
  • stuffy nose

For Healthcare Professionals

Applies to dronabinol: oral capsule, oral solution


Very common (10% or more): Elation (up to 24%), feeling high/easy laughing (up to 24%), heightened awareness (up to 24%)

Common (1% to 10%): Abnormal thinking, euphoria, paranoid reaction

Frequency not reported: Anxiety/nervousness, confusion, depersonalization, depression, hallucinations, nightmares

Postmarketing reports: Delirium, disorientation, insomnia, panic attack


Common (1% to 10%): Abdominal pain, nausea, vomiting

Frequency not reported: Diarrhea, fecal incontinence

Postmarketing reports: Lip swelling, oral lesions

Nervous system

Common (1% to 10%): Dizziness, somnolence

Frequency not reported: Amnesia, ataxia, headache, speech difficulties

Postmarketing reports: Fatigue, loss of consciousness, movement disorder, seizure/seizure-like activity, syncope


Frequency not reported: Flushing, hypotension, palpitations, tachycardia, vasodilation/facial flush


Frequency not reported: Asthenia, chills, malaise, tinnitus

Postmarketing reports: Fall, fatigue


Frequency not reported: Cough, rhinitis, sinusitis

Postmarketing reports: Throat tightness


Frequency not reported: Conjunctival injection, vision difficulties


Frequency not reported: Sweating

Postmarketing reports: Disseminated rash, hives, skin burning


Frequency not reported: Hepatic enzyme elevation


Frequency not reported: Myalgia


Frequency not reported: Anorexia

Editorial References and Review

Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/3/2022.

Source: Drugs.com Marinol (www.drugs.com/marinol.html).