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Commonly reported side effects of losartan include: asthenia, chest pain, diarrhea, fatigue, and hypoglycemia. Other side effects include: hyperkalemia, hypotension, and orthostatic hypotension. See below for a comprehensive list of adverse effects.
For the ConsumerApplies to losartan: oral tablet
Oral route (Tablet)
When pregnancy is detected, discontinue losartan as soon as possible. Drugs that act directly on the renin-angiotensin system can cause injury or death to the developing fetus.
Along with its needed effects, losartan may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking losartan:
More common
Rare
Incidence not known
Some side effects of losartan may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
Less common
Rare
For Healthcare Professionals
Applies to losartan: oral tablet
GeneralThe most common adverse reactions were upper respiratory infection and dizziness.
RespiratoryCommon (1% to 10%): Nasal congestion, upper respiratory infection, sinusitis, pharyngitis, cough, sinus disorder
Uncommon (0.1% to 1%): Dyspnea
Frequency not reported: Bronchitis, pharyngeal discomfort, epistaxis, rhinitis, respiratory congestion
GastrointestinalCommon (1% to 10%): Abdominal pain, nausea, diarrhea, dyspepsia
Uncommon (0.1% to 1%): Obstipation, vomiting
Frequency not reported: Constipation, dental pain, dry mouth, flatulence, gastritis
MusculoskeletalCommon (1% to 10%): Muscle cramp, back pain, leg pain, myalgia
Frequency not reported: Arm pain, hip pain, joint swelling, knee pain, musculoskeletal pain, shoulder pain, stiffness, arthralgia, arthritis, fibromyalgia, muscle weakness
Postmarketing reports: Rhabdomyolysis
RenalCommon (1% to 10%): Renal impairment, renal failure, BUN increased, serum creatinine increased
Nervous systemCommon (1% to 10%): Dizziness, headache, vertigo
Uncommon (0.1% to 1%): Somnolence
Rare (less than 0.1%): Paresthesia, syncope, cerebrovascular accident
Frequency not reported: Ataxia, hypesthesia, memory impairment, migraine, peripheral neuropathy, tremor, taste perversion, tinnitus
OtherCommon (1% to 10%): Asthenia/fatigue, edema/swelling, chest pain
Frequency not reported: Facial edema, fever, orthostatic effects
Postmarketing reports: Malaise
MetabolicCommon (1% to 10%): Hyperkalemia, serum potassium increased, hypoglycemia
Frequency not reported: Anorexia, gout
Postmarketing reports: Hyponatremia
CardiovascularCommon (1% to 10%): Orthostatic hypotension
Uncommon (0.1% to 1%): Palpitation, angina pectoris
Rare (less than 0.1%): Atrial fibrillation
Frequency not reported: Second degree atrioventricular block, hypotension, myocardial infarction, sinus bradycardia, tachycardia, ventricular tachycardia, ventricular fibrillation, flushing
Postmarketing reports: Vasculitis
PsychiatricCommon (1% to 10%): Insomnia
Uncommon (0.1% to 1%): Sleep disorder
Frequency not reported: Anxiety, anxiety disorder, confusion, depression, dream abnormality, libido decreased, nervousness, panic disorder
HematologicCommon (1% to 10%): Anemia
Rare (less than 0.1%): Hemolysis
Postmarketing reports: Thrombocytopenia, hemoglobin decreased, hematocrit decreased
DermatologicUncommon (0.1% to 1%): Urticaria, pruritus, rash
Rare (less than 0.1%): Angioedema, superficial peeling of palms
Frequency not reported: Alopecia, dermatitis, dry skin, ecchymosis, erythema, photosensitivity, sweating
Postmarketing reports: Erythroderma
HepaticRare (less than 0.1%): ALT increased
Postmarketing reports: Hepatitis, liver enzymes increased, serum bilirubin increased, pancreatitis, liver function abnormalities
GenitourinaryFrequency not reported: Impotence, nocturia, urinary frequency, urinary tract infection
OcularFrequency not reported: Blurred vision, burning/stinging in the eye, conjunctivitis, visual acuity decreased
ImmunologicFrequency not reported: Flu-like symptoms
Postmarketing reports: Anaphylactic reactions, hypersensitivity reactions
Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/3/2022.
Source: Drugs.com Losartan Potassium (www.drugs.com/losartan.html).
May 9, 2020
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