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Lopid

Generic Name: Gemfibrozil (jem FI broe zil)
Brand Name: Lopid
Easy-to-read patient leaflet for Lopid. Includes indications, proper use, special instructions, precautions, and possible side effects.

Average Savings for gemfibrozil (generic): 41.62%
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Drug Information:
This is not a list of all drugs or health problems that interact with Lopid (Gemfibrozil). Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Lopid (Gemfibrozil) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor. Use Lopid (Gemfibrozil) as ordered by your doctor. Read all information given to you. Follow all instructions closely. Learn more

Lopid Side Effects

Lopid Side Effects

Note: This document contains side effect information about gemfibrozil. Some of the dosage forms listed on this page may not apply to the brand name Lopid.

In Summary

Common side effects of Lopid include: malignant neoplasm, pancreatitis, dyspepsia, and cholelithiasis. Other side effects include: abdominal pain. See below for a comprehensive list of adverse effects.

For the Consumer

Applies to gemfibrozil: oral tablet

Along with its needed effects, gemfibrozil (the active ingredient contained in Lopid) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking gemfibrozil:

More common

  • Bladder pain
  • bloody or cloudy urine
  • cough or hoarseness
  • difficult, burning, or painful urination
  • fever or chills
  • frequent urge to urinate
  • lower back or side pain

Incidence not known

  • Black, tarry stools
  • chest pain
  • dark-colored urine
  • indigestion
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • muscle cramps or spasms
  • muscle pain or stiffness
  • muscular pain, tenderness, wasting, or weakness
  • pale skin
  • severe nausea or vomiting
  • shortness of breath
  • sore throat
  • sores, ulcers, or white spots on the lips or in the mouth
  • stomach pain
  • swollen glands
  • troubled breathing with exertion
  • unusual bleeding or bruising
  • unusual tiredness or weakness

Some side effects of gemfibrozil may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Acid or sour stomach
  • bad, unusual, or unpleasant (after) taste
  • belching
  • burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  • change in taste
  • diarrhea
  • heartburn
  • stomach discomfort or upset

Less common

  • Difficulty having a bowel movement (stool)
  • dizziness or lightheadedness
  • feeling of constant movement of self or surroundings
  • headache
  • nausea
  • sensation of spinning
  • skin rash, encrusted, scaly and oozing
  • vomiting

For Healthcare Professionals

Applies to gemfibrozil: compounding powder, oral tablet

General

The most frequently reported side effects were gastrointestinal reactions and included dyspepsia, abdominal pain, diarrhea, nausea, vomiting, acute appendicitis, constipation, and flatulence.

Gastrointestinal

Very common (10% or more): Dyspepsia (19.6%)

Common (1% to 10%): Abdominal pain, acute appendicitis, diarrhea, nausea, vomiting, constipation, flatulence

Rare (less than 0.1%): Pancreatitis

Frequency not reported: Colitis

Nervous system

Common (1% to 10%): Headache

Rare (less than 0.1%): Peripheral neuropathy, paresthesia, dizziness, somnolence

Frequency not reported: Peripheral neuritis, convulsions, syncope, hyperesthesia, taste perversion, intracerebral hemorrhage

Hepatic

Rare (less than 0.1%): Hepatitis, cholestatic jaundice, cholelithiasis, cholecystitis, hepatic function abnormal

Frequency not reported: ALT increased, AST increased, bilirubin increased, alkaline phosphatase increased

Cardiovascular

Uncommon (0.1% to 1%): Atrial fibrillation

Frequency not reported: Extrasystoles, vasculitis, peripheral vascular disease

Dermatologic

Common (1% to 10%): Eczema, rash

Rare (less than 0.1%): Angioedema, urticaria, exfoliative dermatitis, dermatitis, pruritus, alopecia, photosensitivity reaction

Other

Common (1% to 10%): Fatigue, vertigo

Rare (less than 0.1%): Creatine phosphokinase increased

Frequency not reported: Weight loss, viral infections, bacterial infections

Musculoskeletal

Rare (less than 0.1%): Myopathy, myalgia, painful extremities, arthralgia, synovitis, rhabdomyolysis, myositis, muscular weakness

Frequency not reported: Lupus-like syndrome, myasthenia

Hematologic

Rare (less than 0.1%): Bone marrow failure, severe anemia, thrombocytopenia, leukopenia, eosinophilia, hemoglobin decreased, hematocrit decreased, WBC decreased

Frequency not reported: Anemia, bone marrow hypoplasia

Ocular

Rare (less than 0.1%): Blurred vision

Frequency not reported: Retinal edema, cataracts

Genitourinary

Rare (less than 0.1%): Erectile dysfunction

Frequency not reported: Impotence, male fertility decreased

Psychiatric

Rare (less than 0.1%): Libido decreased, depression

Frequency not reported: Confusion

Respiratory

Rare (less than 0.1%): Laryngeal edema

Renal

Frequency not reported: Renal dysfunction, renal failure

Oncologic

Frequency not reported: Hepatoma

Immunologic

Frequency not reported: Positive antinuclear antibody, anaphylaxis

Editorial References and Review

Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.

Source: Drugs.com Lopid (www.drugs.com/lopid.html).