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Livalo

Generic Name: pitavastatin (pit AV a STAT in)
Brand Names: Livalo, Zypitamag
Livalo is used to treat high cholesterol in adults (hypercholesterolemia). Learn about side effects, interactions and indications.
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Drug Information:
Livalo (pitavastatin) belongs to a group of drugs called HMG CoA reductase inhibitors, or "statins." Livalo is used together with diet to lower blood levels of "bad" Cholesterol (low-density lipoprotein, or LDL) and triglyceRides, to increase levels of "good" Cholesterol (high-density lipoprotein, or HDL), and to lower triglyceRides (a type of fat in the blood). Livalo is used to treat high Cholesterol in adults. Lowering your Cholesterol may help prevent heart disease and hardening of the arteries, conditions that can lead to heart attack, stroke, and vascular disease. Learn more

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Livalo Side Effects

Note: This document contains side effect information about pitavastatin. Some of the dosage forms listed on this page may not apply to the brand name Livalo.

For the Consumer

Applies to pitavastatin: oral tablet

Along with its needed effects, pitavastatin (the active ingredient contained in Livalo) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking pitavastatin:

Less common

  • Difficulty with moving
  • joint pain
  • muscle aching or cramping
  • muscle pains or stiffness
  • pain in the arms and legs
  • swollen joints

Incidence not known

  • Chills
  • clay-colored stools
  • cough
  • dark urine
  • diarrhea
  • difficulty breathing
  • dizziness
  • fever
  • general feeling of discomfort or illness
  • headache
  • loss of appetite
  • muscle spasm
  • nausea
  • runny nose
  • shivering
  • sore throat
  • stomach pain
  • sweating
  • trouble sleeping
  • unusual tiredness or weakness
  • vomiting
  • vomiting of blood
  • yellow eyes or skin

Some side effects of pitavastatin may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

  • Back pain
  • difficulty having a bowel movement

Incidence not known

  • Burning, numbness, tingling, or painful sensations
  • decreased interest in sexual intercourse
  • discouragement
  • feeling sad or empty
  • hives or welts, itching skin, or rash
  • inability to have or keep an erection
  • irritability
  • loss in sexual ability, desire, drive, or performance
  • loss of interest or pleasure
  • loss of memory
  • problems with memory
  • redness of the skin
  • trouble concentrating
  • unsteadiness or awkwardness
  • weakness in the arms, hands, legs, or feet

For Healthcare Professionals

Applies to pitavastatin: oral tablet

General

The most frequently reported side effects have included myalgia, back pain, diarrhea, constipation, and extremity pain.

Gastrointestinal

Common (1% to 10%): Constipation, diarrhea

Postmarketing reports: Abdominal discomfort, abdominal pain, dyspepsia, nausea

Musculoskeletal

Common (1% to 10%): Back pain, myalgia, pain in extremity

Frequency not reported: Arthralgia, rhabdomyolysis, myopathy, myositis, elevated creatinine phosphokinase

Postmarketing reports: Muscle spasm

Hepatic

Frequency not reported: Bilirubin increased, liver enzymes abnormal, elevated transaminases, elevated alkaline phosphatase

Postmarketing reports: Hepatitis, jaundice, fatal hepatic failure, nonfatal hepatic failure

Dermatologic

Frequency not reported: Rash, pruritus, urticaria

Other

Frequency not reported: Influenza, creatine phosphokinase increased, transaminases increased, alkaline phosphatase increased

Postmarketing reports: Asthenia, fatigue, malaise

Nervous system

Frequency not reported: Headache

Postmarketing reports: Dizziness, hypoesthesia, peripheral neuropathy

Metabolic

Frequency not reported: HbA1c elevations, fasting serum glucose elevations, increased blood glucose

Renal

Frequency not reported: Acute renal failure, myoglobinuria

Respiratory

Frequency not reported: Nasopharyngitis

Postmarketing reports: Interstitial lung disease

Hypersensitivity

Frequency not reported: Hypersensitivity reactions including rash, pruritus, and urticaria

Psychiatric

There have been reports of cognitive impairment such as memory loss, forgetfulness, amnesia, memory impairment, and confusion associated with statin use. These reports are generally nonserious, and reversible with drug discontinuation. Time to symptom onset has been reported as 1 day to years with resolution at a median of 3 weeks following discontinuation.

Postmarketing reports: Insomnia, depression

Statin use:

Postmarketing report: Confusion, cognitive impairment, memory loss, forgetfulness, amnesia, memory impairment

Genitourinary

Postmarketing reports: Erectile dysfunction

Immunologic

Statin use:

Postmarketing reports: Immune-mediated necrotizing myopathy

Editorial References and Review

Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/1/2020.

Source: Drugs.com Livalo (www.drugs.com/livalo.html).