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Note: This document contains side effect information about atorvastatin. Some of the dosage forms listed on this page may not apply to the brand name Lipitor.
In SummaryCommon side effects of Lipitor include: hemorrhagic stroke, arthralgia, diarrhea, and nasopharyngitis. Other side effects include: urinary tract infection, insomnia, limb pain, muscle spasm, musculoskeletal pain, myalgia, and nausea. See below for a comprehensive list of adverse effects.
For the ConsumerApplies to atorvastatin: oral tablet
Along with its needed effects, atorvastatin (the active ingredient contained in Lipitor) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking atorvastatin:
Less common or rare
Incidence not known
Some side effects of atorvastatin may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
Less common
Incidence not known
For Healthcare Professionals
Applies to atorvastatin: oral tablet
GeneralThe most frequently reported side effects were nasopharyngitis, arthralgia, diarrhea, pain in extremity, and urinary tract infection.
GastrointestinalVery common (10% or more): Diarrhea (up to 14.1%)
Common (1% to 10%): Dyspepsia, nausea, flatulence, constipation
Uncommon (0.1% to 1%): Abdominal discomfort, eructation, abdominal pain, vomiting, pancreatitis
HepaticCommon (1% to 10%): Blood bilirubin increased, ALT increased, transaminases/hepatic enzymes increased, AST increased, liver function test abnormal, blood alkaline phosphatase increased
Uncommon (0.1% to 1%): Hepatitis
Rare (0.01% to 0.1%): Cholestasis
Very rare (less than 0.1%): Fatal hepatic failure, nonfatal hepatic failure
MusculoskeletalVery common (10% or more): Arthralgia (up to 11.7%)
Common (1% to 10%): Pain in extremity, musculoskeletal pain, muscle spasms, myalgia, joint swelling, back pain, creatine phosphokinase increased
Uncommon (0.1% to 1%): Neck pain, muscle fatigue
Rare (less than 0.1%): Myositis, myopathy, rhabdomyolysis, tendinopathy
Frequency not reported: Immune-mediated necrotizing myopathy
Postmarketing reports: Tendon rupture
HematologicRare (less than 0.1%): Thrombocytopenia
Nervous systemCommon (1% to 10%): Headache
Uncommon (0.1% to 1%): Paresthesia, dizziness, hypoesthesia, dysgeusia, amnesia
Rare (less than 0.1%): Peripheral neuropathy
Frequency not reported: Nonfatal hemorrhagic stroke
Postmarketing reports: Cognitive impairment, memory loss, forgetfulness, memory impairment
EndocrineVery rare (less than 0.01%): Gynecomastia
HypersensitivityCommon (1% to 10%): Allergic reactions
Rare (less than 0.1%): Anaphylaxis, hypersensitivity reaction
PsychiatricCommon (1% to 10%): Insomnia
Uncommon (0.1% to 1%): Nightmare
Postmarketing reports: Confusion, depression
GenitourinaryCommon (1% to 10%): Urinary tract infection
Uncommon (0.1% to 1%): White blood cells urine positive, erectile dysfunction
DermatologicUncommon (0.1% to 1%): Rash, pruritus, urticaria, alopecia
Rare (less than 0.1%): Angioneurotic edema/angioedema, bullous rashes, erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis
Frequency not reported: Urticaria
CardiovascularCommon (1% to 10%): Cardiovascular death
RespiratoryVery common (10% or more): Nasopharyngitis (up to 12.9%)
Common (1% to 10%): Pharyngolaryngeal pain, epistaxis
Uncommon (0.1% to 1%): Asthma
Rare (less than 0.1%): Sinusitis, pharyngitis
Frequency not reported: Interstitial lung disease
OcularUncommon (0.1% to 1%): Vision blurred
Rare (less than 0.1%): Visual disturbance
OtherCommon (1% to 10%): Non-cardiovascular death
Uncommon (0.1% to 1%): Deafness, tinnitus, malaise, asthenia, influenza, infection, chest pain, peripheral edema, fatigue, pyrexia
Rare (0.01% to 0.1%): Injury
Very rare (less than 0.01%): Hearing loss
MetabolicCommon (1% to 10%): Hyperglycemia
Uncommon (0.1% to 1%): Anorexia, hypoglycemia, weight increased
Frequency not reported: Diabetes mellitus
Medically reviewed by USARx EDITORIAL TEAM Last updated on 1/3/2022.
Source: Drugs.com Lipitor (www.drugs.com/lipitor.html).
May 9, 2022
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